Patents by Inventor Dwayne G. Stupack

Dwayne G. Stupack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions useful for targeting activated vitronectin receptor alphavbeta3
    Publication number: 20040005550
    Abstract: The present invention provides ligands which can selectively bind to activated &agr;v&bgr;3 integrin. A novel monovalent ligand-mimetic (WOW-1 Fab) which includes a single &agr;v integrin-binding domain from multivalent adenovirus penton base is provided. Further, the present invention describes particular compositions of activated &agr;v&bgr;3-specific ligands, such as an antibody which immunoreacts preferentially with activated &agr;v&bgr;3 integrin. The invention also describes methods using an activated &agr;v&bgr;3-specific ligand for diagnostic detection of activated &agr;v&bgr;3 integrin in tissues and for the targeted delivery of therapeutic agents to tissues containing activated &agr;v&bgr;3 integrin.
    Type: Application
    Filed: June 3, 2003
    Publication date: January 8, 2004
    Applicant: The Scripps Research Institute
    Inventors: Sanford J. Shattil, Glen R. Nemerow, Takaaki Hato, Dwayne G. Stupack, Nisar A. Pampori