Abstract: A pressure release device and methods of using the same are disclosed. The pressure release device and/or related methods may be useful for alleviating and/or relieving pressure on skin tissue prone to developing pressure sores and/or tissue that has already developed pressure sores. The pressure release device generally includes one or more relays, logic configured to actuate the one or more relays, one or more motors, and a barrel rotatably connected to at least one of the motor(s) and having one or more straps retractably affixed thereto. Optionally, the pressure release device may be detachably or permanently connected to a surface or frame of a wheelchair.

Abstract: A device is provided for the controlled sampling of fluid into a well formed within an upper surface, in which the well may be filled under dynamic wetting conditions by contacting a droplet on the upper surface with the top of the well. Wetting is supported by the increased hydrophilicity of the upper surface relative to that of the well side wall. The relative difference in hydrophilicity may be achieved by providing an upper surface with greater roughness than the side wall, effectively amplifying the hydrophilicity of the upper surface relative to that of the side wall. Wells are preferably formed in an unpolished surface of a siliconwafer, and can achieve a stable film with micron depth and an aspect ratio in excess of 100.

Abstract: Systems and methods are disclosed for tracking the content of building information models. Embodiments include various computer-implemented methods for the tagging of BIM information, and for the monitoring of modification events involving BIM information. In addition, activities involving physical elements associated with BIM information are tracked. Providers of BIM content can tag content prior to distribution, enabling an internet-based service to track usage, enabling improved service to consumers of that BIM content. Designers can tag BIM content and BIM elements for tracking during the useful life of a building. Internet based messaging protocols can be used for communication between web services, client services and client applications. Monitoring and communication services function unattended. The system includes integration with BIM design applications, as well as stand-alone, end user system applications and browser interfaces. Analytic tools can be used to report on the tracking data.

Abstract: A method of laser processing of materials and specifically laser induced ablation processes for laser removal of material by impulsive heat deposition (IHD) by direct and specific excitation of short lived vibrations or phonons of the material in such a way as to not generate highly reactive and damaging ions through multiphoton absorption. The heat deposition and ensuing ablation is achieved faster than heat transfer to surrounding tissue by either acoustic or thermal expansion or thermal diffusion. The deposited laser energy is channeled into the ablation process to drive the most efficient ablation process possible with minimal damage to surrounding areas by either ionizing radiation or heat effects.

Abstract: Methods and systems are provided for the soft desorption of analyte from a sample, in which an optical beam absorbed within an irradiate zone of the sample causes vibrational excitations of a component within the sample. The optical beam, providing sufficient energy to superheat the component, is provided for a time interval that is less than the time duration required for the loss of energy out of the irradiated zone due to thermal diffusion and acoustic expansion. The superheated component thus drives ablation within the irradiated zone, resulting in the soft desorption of analyte without ionization and fragmentation. The ejected ablation plume may be directed towards the inlet of a mass analysis device for detection of the desorbed analyte, which is preferably ionized by a linear resonant photo-ionization step.

Abstract: The present invention provides a method of laser processing of materials, specifically laser induced ablation processes for laser removal of material particularly important in medical and dental applications in which the laser removal of material should be done in such a way as to not damage any of the surrounding soft or hard biomaterial. The ablation process is achieved by impulsive heat deposition (IHD) by direct and specific excitation of short lived vibrations or phonons of the material in such a way as to not generate highly reactive and damaging ions through multiphoton absorption. The heat deposition and ensuing ablation process under prescribed time and wavelength conditions for laser irradiation is achieved faster than heat transfer to surrounding tissue by either acoustic or thermal expansion or thermal diffusion that otherwise would lead to excess heat related damage.

Abstract: A device for generating a high power frequency converted laser beam includes a nonlinear optical crystal having an entrance surface and a curved surface. The nonlinear optical crystal is configured to receive at least one laser beam at the entrance surface and provide a frequency converted beam through a frequency conversion process. The device also includes an optical coating coupled to the curved surface. The reflectance of the optical coating is greater than 50% at a wavelength of the frequency converted beam. Additionally, the far field divergence angle of the frequency converted beam increases after reflection off the curved surface. The device further includes a heat sink in thermal contact with the optical coating.

Abstract: Methods and systems are provided for the soft desorption of analyte from a sample, in which an optical beam absorbed within an irradiate zone of the sample causes vibrational excitations of a component within the sample. The optical beam, providing sufficient energy to superheat the component, is provided for a time interval that is less than the time duration required for the loss of energy out of the irradiated zone due to thermal diffusion and acoustic expansion. The superheated component thus drives ablation within the irradiated zone, resulting in the soft desorption of analyte without ionization and fragmentation. The ejected ablation plume may be directed towards the inlet of a mass analysis device for detection of the desorbed analyte, which is preferably ionized by a linear resonant photo-ionization step.

Abstract: The present invention relates to methods for laser surgery and growth factor stimulation for ultra-precision surgery with healing. The method is achieved by cutting biological tissue using an ultrafast laser, which produces laser pulses less than 10 picosecond in duration, to induce a cold ablation process in order to avoid the formation of carbonaceous or other materials that cannot be removed efficiently or completely from the wounded area through natural healing mechanisms. By use of femtosecond lasers, a negligible amount of debris is generated and an outer layer of intact but non viable cells are created principally through shock wave induce damage and ionizing radiation effects induced by multiphoton absorption of ultrashort laser pulses. The normal healing process is blocked by this outer layer of cells as all cell contacts are still intact. Therefore the healing process must be stimulated.

Abstract: A laser system capable of efficient production of high energy sub-nanosecond pulses in the 2-15 ?m spectral region is disclosed. Diode pumped solid state lasers are used as pump sources. The system design is simple, reliable and compact allowing for easy integration. The laser system includes a combination of compact solid-state ˜1 micron laser sources, producing high power picosecond pulses, with optical parametric amplification and a quasi-continuous wave laser for seeding the amplification process that enables the efficient conversion of the high power ˜1 micron laser radiation to tuneable mid-infrared sub-ns pulses. New parametric processes are presented for achieving high gains in bulk nonlinear crystals. Furthermore, a method of exceeding the fundamental conversion efficiency limit of direct three wave mixing is presented.

Abstract: The present invention discloses a laser amplifier with high gain and low thermally induced optical aberrations on the amplified laser beam. The amplifier designs allow simple multipass configurations to optimally extract the gain and reduce thermally induced index of refraction aberrations, making it possible to obtain an amplified laser beam of high quality combined with very high overall gains comparable to those achievable with expensive regenerative amplifiers. The amplifier includes a thin active laser solid to create the population inversion and associated heat generation within the thin laser active solid possible for the desired gain value. The system includes a cooling device in thermal contact with the thin active laser solid to provide good heat transport and high reflectivity coatings at the wavelengths of the pump and laser wavelengths. The pump light sources are laser diodes tuned to the maximum absorption of the laser active material.

Abstract: A device for generating a high power frequency converted laser beam includes a nonlinear optical crystal having an entrance surface and a curved surface. The nonlinear optical crystal is configured to receive at least one laser beam at the entrance surface and provide a frequency converted beam through a frequency conversion process. The device also includes an optical coating coupled to the curved surface. The reflectance of the optical coating is greater than 50% at a wavelength of the frequency converted beam. Additionally, the far field divergence angle of the frequency converted beam increases after reflection off the curved surface. The device further includes a heat sink in thermal contact with the optical coating.

Abstract: A device for generating a frequency converted laser beam includes a nonlinear crystal having a first end face and a second end face opposed to the first end face. The nonlinear crystal is configured to receive at least one input laser beam at the first end face and output a frequency converted beam at the second face. A beam waist of the at least one input laser beam is positioned between the first end face and the second end face during a frequency conversion process. The device also includes a second crystal having a first end face bonded to the second end face of the nonlinear crystal and a second end face opposed to the first end face. A beam diameter of the frequency converted beam at the first end face of the second crystal is less than a beam diameter of the frequency converted beam at the second end face of the second crystal.

Abstract: The present invention discloses a laser amplifier with high gain and low thermally induced optical aberrations on the amplified laser beam. The amplifier designs allow simple multipass configurations to optimally extract the gain and reduce thermally induced index of refraction aberrations, making it possible to obtain an amplified laser beam of high quality combined with very high overall gains comparable to those achievable with expensive regenerative amplifiers. The amplifier includes a thin active laser solid to create the population inversion and associated heat generation within the thin laser active solid possible for the desired gain value. The system includes a cooling device in thermal contact with the thin active laser solid to provide good heat transport and high reflectivity coatings at the wavelengths of the pump and laser wavelengths. The pump light sources are laser diodes tuned to the maximum absorption of the laser active material.

Abstract: The present invention is directed to the creation of optical waveguiding devices from standard optical fibers by the creation of zones of permanently altered refractive index characteristics therein. A high intensity femtosecond laser beam is focused at a predetermined target region in the fiber so as to soften the glass material at the target region. After aligning the focal region with the target region in the fiber there will be relative movement between the focal region and the fiber, which has the effect of sweeping the focal region across the fiber in a predetermined path, so as to create a secondary waveguide path. A portion of the light traveling along the core is removed from the core along the secondary waveguide path such that the device can be utilized as an attenuator, an optical tap, or a polarimeter.

Abstract: The present invention is directed to the creation of zones of permanently altered refractive index characteristics in glass waveguiding devices, including optical fibers and optical waveguides pre-existed in a glass substrate. Such zones in which the refractive index has been permanently altered are created in glass using a very high intensity laser beam which is produced by focusing the light output from an ultrafast pulsed laser at a predetermined target region in the glass. The preferred laser is a Ti:Sapphire amplified, frequency-doubled Erbium-doped fiber laser system, providing light pulses of approximately 100 femtosecond duration, each with an energy of between about 1 nanojoule and 1 millijoule, and preferably at a pulse repetition rate of between 500 Hz and 1 GHz. The repetition rate is chosen to deliver pulses faster than the thermal diffusion time over the dimensions of the volume element being modified.

Abstract: This invention provides a method of acquisition of binary information that has been stored physically in a periodic storage medium. The method, referred to as matrix-method deconvolution (MMD), is useful for use with optical storage media using an optical addressing system that reads and writes binary information in a periodic array of nano-particles. With this MMD method, the density of existing memory systems can be boosted to between 10 and 100 Terabytes of data per cubic centimeter. This matrix-method deconvolution method compensates for the effects of the optical addressing system's point spread function. Prior knowledge of a system's point spread function and inter memory-center spacing is used.

Abstract: A method for providing three dimensional optical memory storage for computers. The method comprises subjecting a nanocomposite to irradiation. The nanocomposite comprises a matrix of particles of a liquid core resin within an inner shell resin and an outer shell resin. The inner shell resin retains the liquid core resin while the outer shell resin forms a continuous phase of the matrix. The particles of core resin contain at least one photosensitive compound and are in an array in the matrix. The continuous phase is substantially free of photosensitive compound. The irradiation may be a single beam of irradiation selectively focused on individual particles in the array to effect photobleaching of individual particles or a two-photon irradiation of a wavelength to effect photobleaching.

Abstract: This invention provides a method of acquisition of binary information that has been stored physically in a periodic storage medium. The method, referred to as matrix-method deconvolution (MMD), is useful for use with optical storage media using an optical addressing system that reads and writes binary information in a periodic array of nano-particles. With this MMD method, the density of existing memory systems can be boosted to between 10 and 100 Terabytes of data per cubic centimeter. This matrix-method deconvolution method compensates for the effects of the optical addressing system's point spread function. Prior knowledge of a system's point spread function and inter memory-center spacing is used.

Abstract: A laser clamping system for a disc laser medium that includes two heat conductive members (one of which is optically transparent) positioned on either side of a disc laser. Pressure is applied to the conductive members to restrain the disc from deforming under pumping conditions to reduce the lensing effect. Thin disc geometry allows the thermal load of laser material to be much closer to the heat conductive members so that heat dissipation is generally more efficient than that of other geometric configurations (e.g. rod or slab). In disc lasers each part of the laser beam experiences the same temperature gradient so that there is no lensing effect caused by radial temperature distribution. It has been discovered that any resulting lensing effect is disc lasers is mainly from the thermo-mechanical deformation of the disc itself.