Patents by Inventor Dwayne Thomas Friesen

Dwayne Thomas Friesen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for forming active domains dispersed in a matrix
    Patent number: 11364203
    Abstract: Disclosed are processes for forming compositions comprising small domains of an active agent and a matrix material, and methods of using them. A suspension of an active agent, a matrix material, a first solvent, and a second solvent is formed at a temperature T1, heated to a temperature T2 and spray dried.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: June 21, 2022
    Assignee: Bend Reserch, Inc.
    Inventors: David Thomas Vodak, Dwayne Thomas Friesen
  • Multiparticulates of spray-coated drug and polymer on a meltable core
    Patent number: 11116728
    Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: September 14, 2021
    Assignee: Bend Research, Inc.
    Inventors: Dwayne Thomas Friesen, Leah E. Appel, Joshua Richard Shockey, Sanjay Konagurthu, Edward Dennis LaChapelle
  • ACID RESISTANT CAPSULES
    Publication number: 20210220285
    Abstract: An acid resistant capsule comprises at least one hard capsule shell, said shell comprising: an enteric polymer having acid groups; a film-forming aid; and an alkaline material, wherein said alkaline material is present in an amount such that said carboxylic acid groups of said enteric polymer have a degree of ionization of less than 15%.
    Type: Application
    Filed: April 7, 2021
    Publication date: July 22, 2021
    Applicant: Capsugel Belgium NV
    Inventors: Xiongwei David He, Stefaan Jaak Vanquickenborne, Jonathan Leonard Cape, Dwayne Thomas Friesen
  • ORAL REHYDRATION SOLUTION WITH IMPROVED TASTE
    Publication number: 20200383354
    Abstract: Oral rehydration solutions (ORSs), methods of preparing ORSs and methods of delivering rehydration therapy are disclosed herein. In some embodiments, an ORS includes a non-starch viscosity enhancing polymer and a sodium salt. The ORS may include at least approximately 50 millimoles of dissolved sodium per liter. Other embodiments may be described and/or claimed.
    Type: Application
    Filed: May 7, 2020
    Publication date: December 10, 2020
    Inventors: Dwayne Thomas Friesen, Rodney James Ketner, Michael Edward Grass
  • Oral rehydration solution with improved taste
    Patent number: 10653168
    Abstract: Oral rehydration solutions (ORSs), methods of preparing ORSs and methods of delivering rehydration therapy are disclosed herein. In some embodiments, an ORS includes a non-starch viscosity enhancing polymer and a sodium salt. The ORS may include at least approximately 50 millimoles of dissolved sodium per liter. Other embodiments may be described and/or claimed.
    Type: Grant
    Filed: October 1, 2013
    Date of Patent: May 19, 2020
    Assignee: Sweetwater Solutions, LLC
    Inventors: Dwayne Thomas Friesen, Rodney James Ketner, Michael Edward Grass
  • Colloidal dispersion comprising HPMCAS
    Patent number: 10471152
    Abstract: The present disclosure relates to compositions of an aqueous colloidal dispersion of hydroxypropyl methyl cellulose acetate succinate (HPMCAS), and methods for making such colloidal dispersions.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: November 12, 2019
    Assignee: Capsugel Belgium NV
    Inventors: Jonathan Leonard Cape, Warren Kenyon Miller, Dwayne Thomas Friesen, Hassan Benameur, Maryline Clauzel, David Thomas Vodak
  • MULTIPARTICULATES OF SPRAY-COATED DRUG AND POLYMER ON A MELTABLE CORE
    Publication number: 20190307702
    Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.
    Type: Application
    Filed: June 13, 2019
    Publication date: October 10, 2019
    Applicant: Bend Research, Inc.
    Inventors: Dwayne Thomas Friesen, Leah E. Appel, Joshua Richard Shockey, Sanjay Konagurthu, Edward Dennis LaChapelle
  • Spray drying processes for forming solid amorphous dispersions of drugs and polymers
    Patent number: 10383941
    Abstract: Spray drying processes are used to form pharmaceutical compositions comprising a solid amorphous dispersion of a drug and a polymer.
    Type: Grant
    Filed: August 3, 2004
    Date of Patent: August 20, 2019
    Assignee: Bend Research, Inc.
    Inventors: Ronald Arthur Beyerinck, Daniel Elmont Dobry, Dwayne Thomas Friesen, Dana Marie Settell, Roderick Jack Ray
  • ACID RESISTANT CAPSULES
    Publication number: 20190240160
    Abstract: An acid resistant capsule comprises at least one hard capsule shell, said shell comprising: an enteric polymer having acid groups; a film-forming aid; and an alkaline material, wherein said alkaline material is present in an amount such that said carboxylic acid groups of said enteric polymer have a degree of ionization of less than 15%.
    Type: Application
    Filed: July 20, 2017
    Publication date: August 8, 2019
    Applicant: Capsugel Belgium NV
    Inventors: Xiongwei David He, Stefaan Jaak Vanquickenborne, Jonathan Leonard Cape, Dwayne Thomas Friesen
  • Multiparticulates of spray-coated drug and polymer on a meltable core
    Patent number: 10357462
    Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: July 23, 2019
    Assignee: Ben Research, Inc.
    Inventors: Dwayne Thomas Friesen, Leah E. Appel, Joshua Richard Shockey, Sanjay Konagurthu, Edward Dennis LaChapelle
  • Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
    Patent number: 10357455
    Abstract: A pharmaceutical composition comprises a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer and a lipophilic microphase-forming material. Alternatively, a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer is co-administered with a lipophilic microphase-forming material to an in vivo use environment.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: July 23, 2019
    Assignee: Bend Research, Inc.
    Inventors: Michael E. Perlman, Ravi M. Shanker, Walter C. Babcock, Dwayne Thomas Friesen, Mark D. Rabenstein, Daniel Tod Smithey
  • PHARMACEUTICAL COMPOSITIONS OF AMORPHOUS DISPERSIONS OF DRUGS AND LIPOPHILIC MICROPHASE-FORMING MATERIALS
    Publication number: 20180338915
    Abstract: A pharmaceutical composition comprises a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer and a lipophilic microphase-forming material. Alternatively, a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer is co-administered with a lipophilic microphase-forming material to an in vivo use environment.
    Type: Application
    Filed: July 27, 2018
    Publication date: November 29, 2018
    Applicant: Bend Research, Inc.
    Inventors: Michael E. Perlman, Ravi M. Shanker, Walter C. Babcock, Dwayne Thomas Friesen, Mark D. Rabenstein, Daniel Tod Smithey
  • PROCESS FOR FORMING ACTIVE DOMAINS DISPERSED IN A MATRIX
    Publication number: 20180015041
    Abstract: Disclosed are processes for forming compositions comprising small domains of an active agent and a matrix material, and methods of using them.
    Type: Application
    Filed: October 5, 2015
    Publication date: January 18, 2018
    Applicant: Bend Research, Inc.
    Inventors: David Thomas Vodak, Dwayne Thomas Friesen
  • NOVEL SPRAY NOZZLE AND PROCESS FOR MAKING NANOPARTICLES
    Publication number: 20180000738
    Abstract: Methods for making particulate material include providing a first solution comprising one or more solvents and an active agent, providing a second solution comprising an antisolvent, mixing the first solution with the second solution to form a mixture, atomizing the mixture with a gas to produce droplets, and drying the droplets by directing the droplets into a chamber for removal of the solvent and the antisolvent to produce solid particles. Various apparatuses for producing particulate material in this manner are also provided.
    Type: Application
    Filed: October 5, 2015
    Publication date: January 4, 2018
    Applicant: Bend Research, Inc.
    Inventors: Vikram J. Pansare, Aaron Keith Goodwin, Ronald Arthur Beyerinck, Robert K. Prud'homme, Dwayne Thomas Friesen, David Thomas Vodak
  • COLLOIDAL DISPERSION COMPRISING HPMCAS
    Publication number: 20170281780
    Abstract: The present disclosure relates to compositions of an aqueous colloidal dispersion of hydroxypropyl methyl cellulose acetate succinate (HPMCAS), and methods for making such colloidal dispersions.
    Type: Application
    Filed: August 19, 2015
    Publication date: October 5, 2017
    Applicant: Capsugel Belgium NV
    Inventors: Jonathan Leonard Cape, Warren Kenyon Miller, Dwayne Thomas Friesen, Hassan Benameur, Maryline Clauzel, David Thomas Vodak
  • PHARMACEUTICAL COMPOSITIONS OF AMORPHOUS DISPERSIONS OF DRUGS AND LIPOPHILIC MICROPHASE-FORMING MATERIALS
    Publication number: 20170000733
    Abstract: A pharmaceutical composition comprises a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer and a lipophilic microphase-forming material. Alternatively, a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer is co-administered with a lipophilic microphase-forming material to an in vivo use environment.
    Type: Application
    Filed: September 16, 2016
    Publication date: January 5, 2017
    Applicant: Bend Research, Inc.
    Inventors: Michael E. Perlman, Ravi M. Shanker, Walter C. Babcock, Dwayne Thomas Friesen, Mark D. Rabenstein, Daniel Tod Smithey
  • Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
    Patent number: 9486410
    Abstract: A pharmaceutical composition comprises a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer and a lipophilic microphase-forming material. Alternatively, a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer is co-administered with a lipophilic microphase-forming material to an in vivo use environment.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: November 8, 2016
    Assignee: Bend Research, Inc.
    Inventors: Michael E. Perlman, Ravi M. Shanker, Walter C. Babcock, Dwayne Thomas Friesen, Mark D. Rabenstein, Dan Tod Smithey
  • Solid compositions of low-solubility drugs and poloxamers
    Patent number: 8974823
    Abstract: Solid compositions of low-solubility drugs and poloxamers that provide concentration enhancement when administered to an aqueous environment of use are disclosed.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: March 10, 2015
    Assignee: Bend Research, Inc.
    Inventors: Daniel Tod Smithey, Dwayne Thomas Friesen, Warren Kenyon Miller, Walter Christian Babcock
  • ORAL REHYDRATION SOLUTION WITH IMPROVED TASTE
    Publication number: 20140370144
    Abstract: Oral rehydration solutions (ORSs), methods of preparing ORSs and methods of delivering rehydration therapy are disclosed herein. In some embodiments, an ORS includes a non-starch viscosity enhancing polymer and a sodium salt. The ORS may include at least approximately 60 millimoles of dissolved sodium per liter. Other embodiments may be described and/or claimed.
    Type: Application
    Filed: June 12, 2013
    Publication date: December 18, 2014
    Inventors: Dwayne Thomas Friesen, Rodney James Ketner, Michael Edward Grass
  • ORAL REHYDRATION SOLUTION WITH IMPROVED TASTE
    Publication number: 20140370145
    Abstract: Oral rehydration solutions (ORSs), methods of preparing ORSs and methods of delivering rehydration therapy are disclosed herein. In some embodiments, an ORS includes a non-starch viscosity enhancing polymer and a sodium salt. The ORS may include at least approximately 50 millimoles of dissolved sodium per liter. Other embodiments may be described and/or claimed.
    Type: Application
    Filed: October 1, 2013
    Publication date: December 18, 2014
    Applicant: Sweetwater Solutions, LLC
    Inventors: Dwayne Thomas Friesen, Rodney James Ketner, Michael Edward Grass