Abstract: A novel 3-D encoding scintillation camera which has improved light collection and internal light spreading properties which enhance its use in the field of nuclear medicine is disclosed. The scintillation camera, which is useful for human organ imaging, comprises: (a) a scintillator means of thickness coordinated to correspond generally with the energy of gamma-rays received; (b) photodetector means for detecting the scintillation photons; (c) background light filter means positioned between the scintillator means and the plurality of photodetectors; (d) analog-to-digital converter network means capable of processing pulses from the plurality of photodetectors; and (e) means for analyzing each scintillation event before storing the information in a digital memory. Reflecting means capable of transmitting gamma-rays and reflecting the resulting light photons at about a 180.degree. angle may be optically coupled to the entrance face of the scintillator means.