Patents by Inventor Dylan Deng

Dylan Deng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody drug conjugates
    Patent number: 10590165
    Abstract: There is disclosed a Dolastatin derivative, conjugated to an antibody, comprising a Dolastatin derivative moiety of Formula IV.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: March 17, 2020
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Dylan Deng, Hong Zhang
  • Antibody Drug Conjugates
    Publication number: 20170224835
    Abstract: There is disclosed antibody drug conjugates having anthracycline derivative drug moieties that provide improved safety and cell killing efficacy, wherein the anthracycline derivative drug moieties substitute an hydroxymethyl ketone moiety for an hydrazide or hydroxamate moiety. The disclosed cytotoxic agents (i.e., drug moieties) are conjugated to an antibody via either a Cys or a Lys residue. For Lys conjugation, the DAR (drug antibody ratio) of the majority of the ADC is 2 whereas the DAR of the majority of ADC is 4 when conjugation occurs on a Cys residue.
    Type: Application
    Filed: February 5, 2016
    Publication date: August 10, 2017
    Applicant: Sorrento Therapeutics, Inc.
    Inventors: Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Dylan Deng, Hong Zhang, Zheng Yan
  • Antibody Drug Conjugates
    Publication number: 20170190736
    Abstract: There is disclosed a Dolastatin derivative, conjugated to an antibody, comprising a Dolastatin derivative moiety of Formula IV.
    Type: Application
    Filed: January 28, 2016
    Publication date: July 6, 2017
    Applicant: Sorrento Therapeutics, Inc.
    Inventors: Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Dylan Deng, Hong Zhang