Abstract: The invention relates to compounds, methods and compositions for improving on nucleic acid polymerization, including DNA replication by in vitro primer extension to generate, for example, polymers for nanopore-based single molecule sequencing of a DNA template. A nucleic acid polymerase reaction composition is provided with polymerization enhancement moieties, which allows enhanced DNA polymerase activity with nucleotide analogs, resulting in improved length of primer extension products for sequencing applications.

Abstract: A bait station for pest control, the bait station comprising: an enclosure defining an access chamber and a bait chamber, said access chamber including at least one entry port for permitting entry of a pest into said enclosure, said bait chamber configured to hold therein bait material harmful to the pest; and a load sensing module arranged in the bait chamber for sensing changes in weight of bait material positioned in said bait chamber and operable to output signal indicative of sensed changes in weight of the bait material and transmit said output signal to a remote location.

Abstract: Systems, methods and articles that provide dynamic calibration of eye tracking systems for wearable heads-up displays (WHUDs). The eye tracking system may determine a user's gaze location on a display of the WHUD utilizing a calibration point model that includes a plurality of calibration points. During regular use of the WHUD by the user, the calibration point model may be dynamically updated based on the user's interaction with user interface (UI) elements presented on the display. The UI elements may be specifically designed (e.g., shaped, positioned, displaced) to provide in-use and on-going dynamic calibration of the eye tracking system, which in at least some implementations may be unnoticeable to the user.

Abstract: Systems, methods and articles that provide dynamic calibration of eye tracking systems for wearable heads-up displays (WHUDs). The eye tracking system may determine a user's gaze location on a display of the WHUD utilizing a calibration point model that includes a plurality of calibration points. During regular use of the WHUD by the user, the calibration point model may be dynamically updated based on the user's interaction with user interface (UI) elements presented on the display. The UI elements may be specifically designed (e.g., shaped, positioned, displaced) to provide in-use and on-going dynamic calibration of the eye tracking system, which in at least some implementations may be unnoticeable to the user.

Abstract: Systems, methods and articles that provide dynamic calibration of eye tracking systems for wearable heads-up displays (WHUDs). The eye tracking system may determine a user's gaze location on a display of the WHUD utilizing a calibration point model that includes a plurality of calibration points. During regular use of the WHUD by the user, the calibration point model may be dynamically updated based on the user's interaction with user interface (UI) elements presented on the display. The UI elements may be specifically designed (e.g., shaped, positioned, displaced) to provide in-use and on-going dynamic calibration of the eye tracking system, which in at least some implementations may be unnoticeable to the user.

Abstract: Systems, methods and articles that provide dynamic calibration of eye tracking systems for wearable heads-up displays (WHUDs). The eye tracking system may determine a user's gaze location on a display of the WHUD utilizing a calibration point model that includes a plurality of calibration points. During regular use of the WHUD by the user, the calibration point model may be dynamically updated based on the user's interaction with user interface (UI) elements presented on the display. The UI elements may be specifically designed (e.g., shaped, positioned, displaced) to provide in-use and on-going dynamic calibration of the eye tracking system, which in at least some implementations may be unnoticeable to the user.

Abstract: Systems, methods and articles that provide dynamic calibration of eye tracking systems for wearable heads-up displays (WHUDs). The eye tracking system may determine a user's gaze location on a display of the WHUD utilizing a calibration point model that includes a plurality of calibration points. During regular use of the WHUD by the user, the calibration point model may be dynamically updated based on the user's interaction with user interface (UI) elements presented on the display. The UI elements may be specifically designed (e.g., shaped, positioned, displaced) to provide in-use and on-going dynamic calibration of the eye tracking system, which in at least some implementations may be unnoticeable to the user.

Abstract: Systems, methods and articles that provide dynamic calibration of eye tracking systems for wearable heads-up displays (WHUDs). The eye tracking system may determine a user's gaze location on a display of the WHUD utilizing a calibration point model that includes a plurality of calibration points. During regular use of the WHUD by the user, the calibration point model may be dynamically updated based on the user's interaction with user interface (UI) elements presented on the display. The UI elements may be specifically designed (e.g., shaped, positioned, displaced) to provide in-use and on-going dynamic calibration of the eye tracking system, which in at least some implementations may be unnoticeable to the user.

Abstract: Systems, methods and articles that provide dynamic calibration of eye tracking systems for wearable heads-up displays (WHUDs). The eye tracking system may determine a user's gaze location on a display of the WHUD utilizing a calibration point model that includes a plurality of calibration points. During regular use of the WHUD by the user, the calibration point model may be dynamically updated based on the user's interaction with user interface (UI) elements presented on the display. The UI elements may be specifically designed (e.g., shaped, positioned, displaced) to provide in-use and on-going dynamic calibration of the eye tracking system, which in at least some implementations may be unnoticeable to the user.

Abstract: The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.

Abstract: The present invention relates to compounds of formula I useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative disorders.

Abstract: The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides processes for preparing the compounds of this invention, pharmaceutically acceptable compositions comprising the compounds of the invention, and methods of using the compositions in the treatment of various disorders.

Abstract: The present invention relates to compounds of formula I useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative disorders.

Abstract: A line array loudspeaker, including a first plurality of acoustic drivers each acoustic driver comprising an axis, the first plurality of acoustic drivers arranged so that the axes of first plurality of acoustic drivers are coplanar in a first plane and so that a straight line intersects each axis at a same position on each of the first plurality of acoustic drivers, and a second plurality of acoustic drivers each acoustic driver comprising an axis, the second plurality of acoustic drivers arranged so that the axes of second plurality of acoustic drivers are coplanar in a second plane and so that the straight line intersects each axis at a same position on each of the second plurality of acoustic drivers, in which the first plurality and the second plurality arranged so that the first plane intersects with the second plane along a straight intersection line.

Abstract: The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides processes for preparing the compounds of this invention, pharmaceutically acceptable compositions comprising the compounds of the invention, and methods of using the compositions in the treatment of various disorders.

Abstract: The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides processes for preparing the compounds of this invention, pharmaceutically acceptable compositions comprising the compounds of the invention, and methods of using the compositions in the treatment of various disorders.

Abstract: The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.

Abstract: The invention is directed to a display and method for conducting sound system design. The display is configured to simultaneously show a sound system model comprising both audio components and sound environment components, a plurality of parameters and a graphic representation of a calculated sound system performance attribute. In response to receiving input from the user and without any additional user intervention, the display re-displays a newly-calculated sound system performance attribute such as, for example, a graphic representation in the sound system model of a sound path associated with a user-selected reflected sound identifier. A processor also simulates, based on the sound system configuration, the sound performance that a user would expect to hear positioned in an identified listening position of the sound system model.

Abstract: The invention is directed to a display and method for conducting sound system design. The display is configured to simultaneously show a sound system model comprising both audio components and sound environment components, a plurality of parameters and a graphic representation of a calculated sound system performance attribute. In response to receiving input from the user and without any additional user intervention, the display re-displays a newly-calculated sound system performance attribute such as, for example, a graphic representation in the sound system model of a sound path associated with a user-selected reflected sound identifier. A processor also simulates, based on the sound system configuration, the sound performance that a user would expect to hear positioned in an identified listening position of the sound system model.

Abstract: A line array electroacoustical transducing system includes at least first and second line arrays detachably secured in electrical and mechanical coupling relationships. The assembly may be detachably secured to a base having an amplifier in electrical and mechanical coupling relationships.