Abstract: Fixation system for engaging tissue of a patient including an implantable fixation device having a first arm and a second arm, a first proximal element, a second proximal element, and a coupling member. The system includes a delivery device having a catheter, a shaft extending through the at least one lumen of the catheter, a first proximal element actuator and a second proximal element actuator. The second end portions of the first proximal element actuator and second proximal element actuator can be coupled to at least one of the shaft and the coupling member.

Abstract: Fixation system for engaging tissue of a patient including an implantable fixation device having a first arm and a second arm, a first proximal element, a second proximal element, and a coupling member. The system includes a delivery device having a catheter, a shaft extending through the at least one lumen of the catheter, a first proximal element actuator and a second proximal element actuator. The second end portions of the first proximal element actuator and second proximal element actuator can be coupled to at least one of the shaft and the coupling member.

Abstract: Medical device delivery system including a catheter, handle, lock line handle, and lock line. The catheter includes a proximal end portion and a distal end portion. The handle is coupled to the proximal end portion of the catheter. The lock line handle is releasably coupled to the handle and actuatable between a lock position and an unlock position. The lock line includes a first end portion fixedly coupled to the lock line handle, a second end portion releasably coupled to the lock line handle, and an intermediate portion configured to be releasably coupled to the medical implant disposed proximate the distal end portion of the catheter. Actuating the lock line handle from the lock position toward the unlock position increases tension on the lock line, and actuating the lock line handle from the unlock position toward the lock position decreases tension on the lock line.

Abstract: Medical device delivery system including a catheter, handle, lock line handle, and lock line. The catheter includes a proximal end portion and a distal end portion. The handle is coupled to the proximal end portion of the catheter. The lock line handle is releasably coupled to the handle and actuatable between a lock position and an unlock position. The lock line includes a first end portion fixedly coupled to the lock line handle, a second end portion releasably coupled to the lock line handle, and an intermediate portion configured to be releasably coupled to the medical implant disposed proximate the distal end portion of the catheter. Actuating the lock line handle from the lock position toward the unlock position increases tension on the lock line, and actuating the lock line handle from the unlock position toward the lock position decreases tension on the lock line.

Abstract: Fixation system for engaging tissue of a patient including an implantable fixation device having a first arm and a second arm, a first proximal element, a second proximal element, and a coupling member. The system includes a delivery device having a catheter, a shaft extending through the at least one lumen of the catheter, a first proximal element actuator and a second proximal element actuator. The second end portions of the first proximal element actuator and second proximal element actuator can be coupled to at least one of the shaft and the coupling member.

Abstract: Medical device delivery system including a catheter, handle, lock line handle, and lock line. The catheter includes a proximal end portion and a distal end portion. The handle is coupled to the proximal end portion of the catheter. The lock line handle is releasably coupled to the handle and actuatable between a lock position and an unlock position. The lock line includes a first end portion fixedly coupled to the lock line handle, a second end portion releasably coupled to the lock line handle, and an intermediate portion configured to be releasably coupled to the medical implant disposed proximate the distal end portion of the catheter. Actuating the lock line handle from the lock position toward the unlock position increases tension on the lock line, and actuating the lock line handle from the unlock position toward the lock position decreases tension on the lock line.

Abstract: Stabilizer for a medical delivery system is provided, wherein the medical delivery system has at least two portions translatable relative each other. The stabilizer includes a base and a sled coupled to the base. The sled includes a distal arm including a distal attachment for receiving a first portion of the medical delivery system, and a proximal arm including a proximal attachment for receiving a second portion of the medical delivery system. The sled is translatable relative to the base and the proximal attachment is translatable relative to the proximal arm.

Abstract: The present invention generally relates to devices for imaging the interior of a vessel. The device can involve an elongated body configured to fit within the lumen of a vessel, a rotatable shaft positioned inside the elongated body, and a telescoping element, wherein a portion of the elongated body extends through the telescoping element, in which the elongated body is configured to contain the rotatable shaft inside the telescoping element.

Abstract: Fixation system for fixation of leaflets of a heart valve including an implantable fixation device having a first arm and a second arm, a first proximal element moveable relative to the first arm between a first position and a second position, and a second proximal element moveable relative to the second arm between a first position and a second position. The fixation system includes a delivery device having a catheter, a first proximal element line and a second proximal element line, and a handle having a first and second proximal element line handles coupled to the first proximal element line and the second proximal element line, respectively. The handle can include an interlock moveable between an unlocked position and a locked position.

Abstract: The present disclosure provides a transducer shaping chamber for shaping ultrasound transducers. The transducer shaping chamber includes a transducer coupon carrier having one or more slots. The one or more slots each are geometrically shaped to hold a transducer coupon having a plurality of ultrasonic transducers formed thereon. The transducer shaping chamber includes a first plate disposed over a first side of the transducer coupon carrier. The transducer shaping chamber includes a second plate disposed over a second side of the transducer coupon carrier. The second side is opposite the first side. The transducer shaping chamber is configured to move the first plate and the second plate toward each other so as to push against the transducer coupon carrier from the first and second sides, respectively, until the transducer coupon carrier has been sealed against the first plate and with the second plate.

Abstract: The present disclosure provides methods and apparatus of fabricating a transducer for use in ultrasound imaging. A substrate is provided. The substrate may be a silicon substrate having a first side and a second side opposite the first side. A transducer membrane is formed over the first side of the substrate. The transducer membrane includes a piezoelectric component. A well is formed in the substrate from the second side. A backing material is dispensed onto a first sidewall of the well in a manner so as to create a capillary effect that causes the backing material to wick down the sidewall, across the back side of the substrate exposed by the well, and up a second sidewall of the well. The transducer membrane is deflected so that the transducer membrane has a concave shape.

Abstract: The present disclosure provides various embodiments of an ultrasound catheter for use in intravascular ultrasound (IVUS) imaging. An exemplary IVUS device includes an flexible elongate member having a lumen extending therethrough, and a rotatable imaging core disposed within the lumen. The imaging core is further configured to transmit and receive ultrasound signals through a distal portion of the flexible elongate member. The distal portion of the flexible elongate member includes a first set of material layers, while the proximal portion includes a second set of material layers different than the first set of material layers. The first set of material layers and the second material layers minimize distortion of the ultrasound signals. The first set of material layers further facilitates an average speed of sound through the first set of material layers that is substantially equivalent to a speed of sound through blood.

Abstract: The present disclosure provides a transducer shaping chamber for shaping ultrasound transducers. The transducer shaping chamber includes a transducer coupon carrier having one or more slots. The one or more slots each are geometrically shaped to hold a transducer coupon having a plurality of ultrasonic transducers formed thereon. The transducer shaping chamber includes a first plate disposed over a first side of the transducer coupon carrier. The transducer shaping chamber includes a second plate disposed over a second side of the transducer coupon carrier. The second side is opposite the first side. The transducer shaping chamber is configured to move the first plate and the second plate toward each other so as to push against the transducer coupon carrier from the first and second sides, respectively, until the transducer coupon carrier has been sealed against the first plate and with the second plate.

Abstract: The present disclosure involves a method of fabricating an ultrasound transducer. A piezoelectric polymer is mixed into a solution containing a first chemical and a second chemical to form a viscous film. In some embodiments, the first chemical includes methyl ethyl ketone (MEK), and the second chemical includes dimethylacetamide (DMA). In other embodiments, the first chemical includes cyclohexanone, and the second chemical includes dimethyl sulfoxide (DMSO). The film is coated onto a wafer and then flashed off during the coating. Thereafter, the film is baked. The second chemical is removed during the baking. Thereafter, the film is annealed. In some embodiments, the annealing is performed using an annealing temperature in a range from about 135 degrees Celsius to about 145 degrees Celsius and an annealing duration in a range from about 17 hours to about 19 hours. The film has a ? phase crystallinity greater than 50% after the annealing.

Abstract: The present disclosure provides methods and apparatus of fabricating a transducer for use in ultrasound imaging. A substrate is provided. The substrate may be a silicon substrate having a first side and a second side opposite the first side. A transducer membrane is formed over the first side of the substrate. The transducer membrane includes a piezoelectric component. A well is formed in the substrate from the second side. A backing material is dispensed onto a first sidewall of the well in a manner so as to create a capillary effect that causes the backing material to wick down the sidewall, across the back side of the substrate exposed by the well, and up a second sidewall of the well. The transducer membrane is deflected so that the transducer membrane has a concave shape.

Abstract: The present invention generally relates to devices for imaging the interior of a vessel. The device can involve an elongated body configured to fit within the lumen of a vessel, a rotatable shaft positioned inside the elongated body, and a telescoping element, wherein a portion of the elongated body extends through the telescoping element, in which the elongated body is configured to contain the rotatable shaft inside the telescoping element.

Abstract: The present disclosure provides various embodiments of a sheath for a rotational intravascular probe for insertion into a vasculature. An exemplary sheath includes a flexible portion having a lumen for receiving an ultrasound probe, a distal portion that includes a flexible multi-layer tip, and a transition portion that couples the proximal portion and the distal portion. The multi-layer tip defines a guide wire lumen having a distal guide wire opening and a proximal guide wire opening through a sidewall. In some embodiments, an area between the proximal guide wire entry opening and the flexible proximal portion is supported to prevent kinking and prolapse.

Abstract: An intravascular catheter having an elongated sheath surrounding an elongated flexible inner structure movable relative thereto is provided with various representative embodiments of flushing apparatus carried by the inner structure. Such flushing apparatus is operative in response to movement of the inner structure relative to the sheath to induce a flow of flushing fluid from a source thereof through the interior of the sheath and then discharge the flushing fluid from the sheath. In one embodiment thereof the flushing apparatus includes an impeller structure disposed on the inner structure. In another embodiment thereof the flushing structure includes an annular seal disposed on the inner structure in sliding and sealing engagement with the interior surface of the sheath.