Patents by Inventor Dziyana Kraskouskaya

Dziyana Kraskouskaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sensors for detection of negatively charged phosphate-containing membranes and membrane components
    Patent number: 11851410
    Abstract: This application relates to a method of detecting negatively charged phosphate-containing membranes and membrane components, such as in cell membranes or artificial lipid vesicles, and its use, for example, in detecting apoptosis and bacterial infection.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: December 26, 2023
    Assignee: The Governing Council of the University of Toronto
    Inventors: Patrick Thomas Gunning, Dziyana Kraskouskaya, Aaron Cabral, Bronte Murcar-Evans, Krimo Toutah, Elvin De Araujo
  • STAT INHIBITORY COMPOUNDS AND COMPOSITIONS
    Publication number: 20230159445
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for example, breast cancer and pancreatic cancer.
    Type: Application
    Filed: March 5, 2021
    Publication date: May 25, 2023
    Inventors: Roman FLECK, John PROUDFOOT, Jeff OMEARA, Krishna Kumar GNANASEKARAN, Patrick Thomas GUNNING, Alford Antoine JOHN, Angel Sampedro PALERM, Alla DARWISH, Dziyana KRASKOUSKAYA, Ahmed Magdy Ahmed Mohamed ALI
  • HETEROCYCLE CONTAINING STAT INHIBITORS AND COMPOSITIONS
    Publication number: 20230150946
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for example, breast cancer and pancreatic cancer.
    Type: Application
    Filed: March 5, 2021
    Publication date: May 18, 2023
    Inventors: Roman FLECK, John PROUDFOOT, Krishna Kumar GNANASEKARAN, Patrick Thomas GUNNING, Alford Antoine JOHN, Angel Sampedro PALERM, Alla DARWISH, Dziyana KRASKOUSKAYA
  • ALPHA SUBSTITUTED STAT INHIBITORS AND COMPOSITIONS THEREOF
    Publication number: 20230137956
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for example, breast cancer and pancreatic cancer.
    Type: Application
    Filed: March 5, 2021
    Publication date: May 4, 2023
    Inventors: Roman FLECK, John PROUDFOOT, Jeff OMEARA, Patrick Thomas GUNNING, Angel Sampedro PALERM, Alla DARWISH, Dziyana KRASKOUSKAYA
  • PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20230055961
    Abstract: Provided herein are pentafluorobenzenesulfonamide compounds, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.
    Type: Application
    Filed: May 19, 2022
    Publication date: February 23, 2023
    Inventors: Dziyana KRASKOUSKAYA, Siawash AHMAR, Patrick T. GUNNING, Jeff OMEARA, David Alexander ROSA, Ji Sung PARK, Graham L. SIMPSON, Ayah ABDELDAYEM
  • Excimer forming compounds
    Patent number: 10889554
    Abstract: The present application is directed to excimer forming compounds of Formula I: W—V—[Y]n wherein W is an excimer forming fluorophore, V is a linker moiety, Y is a metal ion coordinating moiety and n is 1, 2 or 3. In particular, the application is directed to excimer forming compounds for the detection of proximally phosphorylated sites including those found on polypeptides, proteins, pyrophosphate and RNA, for example in aqueous solution, polyacrylamide gels blotting membranes, solid-support assays and in cell culture samples.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: January 12, 2021
    Assignee: The Governing Council of the University of Toronto
    Inventors: Patrick Thomas Gunning, Dziyana Kraskouskaya
  • PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF
    Publication number: 20200277268
    Abstract: The present application relates to sulfonamide containing compounds of Formulae (I) and (II) and compositions containing said compounds effective in the treatment of cell proliferative disorders, in particular cancer, and various methods of use thereof.
    Type: Application
    Filed: September 21, 2018
    Publication date: September 3, 2020
    Applicant: Dalriada Therapeutics Inc.
    Inventors: Patrick Thomas Gunning, Ji Sung Park, Siawash Ahmar, David Alexander Rosa, Dziyana Kraskouskaya, David Bakhshinyan, Sheila Singh, Chitra Venugopal, Angelika Berger-Becvar, Mulu Geletu-Heye, Mariya Bogatchenko, Elvin De Araujo, Diana Sina
  • EXCIMER FORMING COMPOUNDS
    Publication number: 20160304473
    Abstract: The present application is directed to excimer forming compounds of Formula I: W—V—[Y]n wherein W is an excimer forming fluorophore, V is a linker moiety, Y is a metal ion coordinating moiety and n is 1, 2 or 3. In particular, the application is directed to excimer forming compounds for the detection of proximally phosphorylated sites including those found on polypeptides, proteins, pyrophosphate and RNA, for example in aqueous solution, polyacrylamide gels blotting membranes, solid-support assays and in cell culture samples.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 20, 2016
    Inventors: Patrick Thomas Gunning, Dziyana Kraskouskaya