Patents by Inventor Dzung C. Thach

Dzung C. Thach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Re-sequencing pathogen microarray
    Patent number: 9430610
    Abstract: The present invention relates to pathogen detection and identification by use of DNA resequencing microarrays. The present invention also provides resequencing microarray chips for differential diagnosis and serotyping of pathogens present in a biological sample. The present invention further provides methods of detecting the presence and identity of pathogens present in a biological sample.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: August 30, 2016
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: Brian K Agan, Eric H Hanson, Russell P Kruzelock, Baochuan Lin, Robb K Rowley, Donald Seto, David A Stenger, Jennifer Johnson, Clark J Tibbetts, Dzung C Thach, Gary J Vora, Elizabeth A Walter, Zheng Wang
  • Diagnosis and Prognosis of Infectious Disease Clinical Phenotypes and other Physiologic States Using Host Gene Expression Biomarkers In Blood
    Publication number: 20110183856
    Abstract: The present invention provides a specific set of gene expression markers from peripheral blood leukocytes that are indicative of a host response to exposure, response, and recovery infectious pathogen infections. The present invention further provides methods for identifying the specific set of gene expression markers, methods of monitoring disease progression and treatment of infectious pathogen infections, methods of prognosing the onset of an infectious pathogen infection, and methods of diagnosing an infectious pathogen infection and identifying the pathogen involved.
    Type: Application
    Filed: February 26, 2010
    Publication date: July 28, 2011
    Applicants: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Brian K. Agan, Eric H. Hanson, Michael J. Jenkins, Baochuan Lin, Chris C. Olsen, Robb K. Rowley, David A. Stenger, Dzung C. Thach, Clark J. Tibbetts, Elizabeth A. Walter, Jinny Lin Liu
  • Cobalt Hexammine as a Potential Therapeutic Against HIV and/or Ebola Virus
    Publication number: 20110027388
    Abstract: Hexaamminecobalt(III) chloride, also called Cohex, reduces the extent of viral infection, including difficult to treat infections caused by Ebola virus and HIV. Disclosed are methods for treating a viral infection, comprising administering to a patient a cobalt(III) hexammine compound in an amount effective to reduce an extent of a viral infection. Also disclosed are kits for delivery of a cobalt(III) hexammine compound by injection.
    Type: Application
    Filed: July 30, 2010
    Publication date: February 3, 2011
    Applicants: The Government of the US, as represented by the Secretary of the Navy
    Inventors: Eddie L. Chang, Lisa Hensley, Dzung C. Thach, Andy Knight, Gene Olinger
  • RE-SEQUENCING PATHOGEN MICROARRAY
    Publication number: 20090170717
    Abstract: The present invention relates to pathogen detection and identification by use of DNA resequencing microarrays. The present invention also provides resequencing microarray chips for differential diagnosis and serotyping of pathogens present in a biological sample. The present invention further provides methods of detecting the presence and identity of pathogens present in a biological sample.
    Type: Application
    Filed: April 10, 2008
    Publication date: July 2, 2009
    Applicants: The Government of the United States of America, as represented by the Secretary of the Navy, The Government of the United States of America, as represented by the Secretary of the Air Force
    Inventors: Brian K. Agan, Eric H. Hanson, Russell P. Kruzelock, Baochuan Lin, Robb K. Rowley, Donald Seto, David A. Stenger, Jennifer Johnson, Clark J. Tibbetts, Dzung C. Thach, Gary J. Vora, Elizabeth A Walter, Zheng Wang
  • METHOD OF USING A COBALT-AMINE BASED METAL COMPLEX AS AN ANTIVIRAL COMPOUND AND A METHOD FOR THE PREPARATION OF FUNCTIONALIZED ANALOGS THEREOF
    Publication number: 20080182835
    Abstract: The present invention is generally directed to a method of prophylaxis against viral infection of a cell or subject or a method of treating a subject infected with a virus including administering an antiviral composition having the general Structure III, wherein each of R1, R2, R3, R4, R5 and R6 is the same or different and includes an N-based ligand donor atom selected from the group consisting of ammonia, primary amine or secondary amine, or salt thereof. The present invention is also generally directed to a method of preparing an antiviral agent including providing a cobalt pentammine salt having a non-amine coordination site and mono-substituting the non-amine coordination site with a functional group incorporating a strong coordinator atom to cobalt to form a CoHex structure of Structure III, in which R1 incorporates the functional group having the strong coordinator atom coordinated with the cobalt atom, or a salt thereof.
    Type: Application
    Filed: November 2, 2007
    Publication date: July 31, 2008
    Applicant: The Government of the US, as represented by the Secretary of the Navy
    Inventors: Eddie L. Chang, James B. Delehanty, Dzung C. Thach, Jason Bongard, Andy Knight