Abstract: To represent broker interest in a security, a system receives broker interest to buy or sell a security at a first price with a minimum trade size, and receives an order with an order trade size. The system determines whether the order trade size is greater than the minimum trade size, and responsive to determining whether the order trade size is greater than the minimum trade size, the system trades at least part of the broker interest against the order if the order trade size is greater than the minimum trade size.

Abstract: A method for altering a characteristic of the ground. The method comprises the steps of preparing a lignocellulosic material, suspending the lignocellulosic material in a slurry to create a lignocellulosic slurry, The method further includes the step of injecting the lignocellulosic slurry below the surface of the ground into a subterranean aperture. The method also comprises the placement of anchoring devices in the ground to alter at least one force experienced by the ground so that the shape of the subterranean aperture into which the solids are transported is altered.

Abstract: A thermal cutting element of an electrosurgical instrument includes a base substrate defining a first side and a second side, at least one insulating layer disposed on at least the first side of the base substrate, and a heater circuit trace disposed on the at least one insulating layer. The thermal cutting element has an operating temperature of at least about 350° C. Temperature Coefficient of Resistance (TCR) of at least about 50 ppm/° C. An electrosurgical instrument and electrosurgical system including the thermal cutting element are also provided.

Abstract: Methods and compositions for decentralized systems for mitigating climate change are provided. In some embodiments, the compositions comprise: one or more first servers operable to store a plurality of first tokens, wherein each one of the plurality of first tokens is associated with fiscal value; one or more second servers operable to store a plurality of second tokens, wherein each one of the plurality of second tokens corresponds to a unit of voting power; one or more project developer nodes operable to transmit project data corresponding to renewable energy or carbon sequestration; one or more auditor nodes operable to verify an identity, validate credentials, perform a project assessment, generate a smart contract, receive signals, and transmit signals; and one or more steward nodes, wherein each one of the one or more steward nodes is operable to stake tokens for voting power and to distribute voting power.

Abstract: A tuned mass damper (TMD) system in combination with a floating offshore wind turbine (FOWT) platform includes a barge type FOWT platform having a hull configured to have a wind turbine tower mounted thereon. A TMD system is mounted in the hull and has a first TMD configured to operate at a first frequency, and a second TMD configured to operate at a second frequency different than the first frequency.

Abstract: A Link 16 terminal. The Link 16 terminal includes a red enclave. The red enclave comprises a Link 16 radio. The Link 16 radio is configured to send commands to Link 16 modems. The commands specify time slots when operations in the commands should be performed by the Link 16 modems. The Link 16 terminal further includes a black enclave physically separated from the red enclave. The black enclave includes a Link 16 modem configured to receive commands from the Link 16 radio. The Link 16 terminal further includes a communication channel configured to facilitate communication between the red enclave and the black enclave. The Link 16 radio is configured to dynamically adjust when commands are sent to the Link 16 modem with respect to time slots specified in the commands based on latency between the Link 16 radio and the Link 16 modem.

Abstract: Methods for treating coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, are described. The methods can be used to reduce the severity of outcomes related to COVID-19, such as hospitalization and ventilation. For example, the methods can involve treatment of a subject with a therapeutic agent that degrades hyaluronan and/or an agent that neutralizes a hyaluronan receptor, e.g., CD44, such as an anti-CD44 antibody.

Abstract: Embodiments of the present invention relate to a structural frame member which includes a brace member that is used to absorb energy when the structural frame is subjected to loadings such as seismic, wind and gravity loads. The brace member is coupled to a restraining member that increases the buckling capacity of the brace member so that the brace member has approximately the same load axial capacity in compression as in tension. Embodiments of the invention also relate to the design, construction and assembly of the connection of the brace member that couples the brace member to a gusset plate which is coupled to the beam and column in the structural frame.

Abstract: A finishing tool control system for an agricultural implement may include a controller communicatively coupled to a first and a second sensor. The controller is configured to control a height of a finishing tool above a soil surface. Further, the first sensor is configured to output a signal indicative of a height of a main frame of the agricultural implement above the soil surface. In response to determining that a height increase of the main frame exceeds a threshold height adjustment, the controller increases the height of the finishing tool. The second sensor is configured to output a signal indicative of the height of the finishing tool of the finishing assembly above the soil surface. Moreover, in response to determining that a height of the finishing assembly above the soil surface is less than a threshold value, the controller increases the height of the finishing tool.

Abstract: To represent broker interest in a security, a system receives broker interest to buy or sell a security at a first price with a minimum trade size, and receives an order with an order trade size. The system determines whether the order trade size is greater than the minimum trade size, and responsive to determining whether the order trade size is greater than the minimum trade size, the system trades at least part of the broker interest against the order if the order trade size is greater than the minimum trade size.

Abstract: The clamping support heads disclosed herein provide a clampable mouth having jaws that can securely hold and permit movement of a variety of different size and/or shape objects. The objects may be quickly attached and quickly removed from the clamping support heads. A repositioning clutch allows for rotational repositioning of a clamped object. The repositioning clutch may include a clutch body attached to a stem of a stand, a friction ring seated to a clutch body, a bearing plate sharing a bearing interface with the friction ring, a clutch shaft extending through the clutch body, the friction ring, and the bearing plate to a terminal end, and a clutch adjustment handle screwed onto the terminal end of the clutch shaft. Rotation of the clutch adjustment handle adjusts compression force on the bearing interface between the friction ring and the bearing plate to secure or release the object from rotation.

Abstract: Indexed collar clamps allow for fast and easy adjustment of an associated telescoping stand, while preventing various underlying components from becoming dislodged from their respective positions over time. A telescoping stand may include an inner tube and an outer tube partially overlapping the inner tube. An overlapping end of the outer tube includes a compliance cut. A bushing is positioned between the inner tube and the outer tube and adjacent the compliance cut. The bushing includes a protrusion that indexes the bushing to an aperture in the outer tube. An indexed collar clamp is positioned over the outer tube and also adjacent the compliance cut. The protrusion from the bushing further indexes the bushing to a slot in the indexed collar clamp.

Abstract: Systems and methods are described herein for a prosthetic device that includes a rigid outer shell socket with an inner surface contour. A prosthetic insert socket is manufactured via a manufacturing process, such as three-dimensional printing, to have an outer contour that corresponds to the inner surface contour of the premade outer shell socket. The prosthetic insert socket is manufactured to have an inner contour that corresponds to a residual limb surface contour of a patient.

Abstract: Disclosed are anti-angiogenic agents that target Pfn1:actin interaction. Also disclosed are compounds for treating ocular diseases or conditions. Further disclosed are compounds for treating cancer.

Abstract: Systems and methods are described herein for a prosthetic device that includes a premade outer shell socket with an inner surface contour. A prosthetic insert socket is manufactured via a manufacturing process, such as three-dimensional printing, to have an outer contour that corresponds to the inner surface contour of the premade outer shell socket. The prosthetic insert socket is manufactured to have an inner contour that corresponds to a residual limb surface contour of a patient.

Abstract: The present disclosure provides methods of preparing a biological specimen for imaging analysis, comprising fixing and clearing the biological specimen and subsequently analyzing the cleared biological specimen using microscopy. Also included are methods of quantifying cells, for example, active populations of cells in response to a stimulant. The present disclosure also provides devices for practicing the described methods. A flow-assisted clearing device provides rapid clearing of hydrogel-embedded biological specimens without the need of specialized equipment such as electrophoresis or perfusion devices.

Abstract: The present disclosure provides methods of preparing a biological specimen for imaging analysis, comprising fixing and clearing the biological specimen and subsequently analyzing the cleared biological specimen using microscopy. Also included are methods of quantifying cells, for example, active populations of cells in response to a stimulant. The present disclosure also provides devices for practicing the described methods. A flow-assisted clearing device provides rapid clearing of hydrogel-embedded biological specimens without the need of specialized equipment such as electrophoresis or perfusion devices.

Abstract: Provided herein are devices, methods, and systems for in situ gene sequencing of a target nucleic acid in a cell in an intact tissue. Methods of screening a candidate agent to determine whether the candidate agent modulates gene expression of a nucleic acid in a cell in an intact tissue are also provided herein.

Abstract: An ion source. The ion source may include a plasma chamber to house a plasma, and an extraction assembly, disposed along a side of the plasma chamber, and comprising at least one extraction aperture. The ion source may further include an antenna assembly, extending through the plasma chamber, along a first axis. The antenna assembly may include a dielectric enclosure, a plurality of conductive antennae, extending along the first axis within the dielectric enclosure.