Patents by Inventor E. David Crawford

E. David Crawford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11737672
    Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation-emission matrix is generated (1002). On-diagonal and off-diagonal components of the excitation-emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation-emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: August 29, 2023
    Assignee: The Regents of the University of Colorado, A Body Corporate
    Inventors: Priya N. Werahera, John Daily, M. Scott Lucia, Adrie van Bokhoven, E. David Crawford, Frank Barnes
  • Publication number: 20230031498
    Abstract: A method and apparatus for treating bone or other infection in a patient to minimize the number of limb amputations which employs a unique, three-dimensional software-controlled electronic phased array amplifier system using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined infected area containing electrically-conductive ionic solutions so as to obtain 100% treatment using low or high voltage, low current that delivers electrical stimulation (ES) using a low DC current through and or around the defined infection treatment area. The minimally invasive treatment of the infection requires no radiation or chemotherapy that could be harmful to the patient.
    Type: Application
    Filed: August 1, 2022
    Publication date: February 2, 2023
    Inventors: RICHARD B. RUSE, E. DAVID CRAWFORD, WILLIAM L. NABORS, SEAN BRUGMAN, SCOTT J. BOHANAN, PAUL ARANGUA
  • Publication number: 20180360320
    Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation-emission matrix is generated (1002). On-diagonal and off-diagonal components of the excitation-emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation-emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.
    Type: Application
    Filed: July 16, 2018
    Publication date: December 20, 2018
    Inventors: Priya N. Werahera, John Daily, M. Scott Lucia, Adrie van Bokhoven, E. David Crawford, Frank Barnes
  • Patent number: 9486625
    Abstract: A method and apparatus for treating a condition in a patient such as BPH, irretractable infection, cyst, fibroid, or any mass such as prostate or breast cancer, skin cancer, melanoma, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined area containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the defined area. The condition is treated or a mass is destroyed with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: November 8, 2016
    Assignee: MedAmp Electronics, LLC
    Inventors: E. David Crawford, William L. Nabors, Sr., Richard B. Ruse, Scott J. Bohanan
  • Publication number: 20150196351
    Abstract: A method and apparatus for treating a condition in a patient such as BPH, irretractable infection, cyst, fibroid, or any mass such as prostate or breast cancer, skin cancer, melanoma, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined area containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the defined area. The condition is treated or a mass is destroyed with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.
    Type: Application
    Filed: February 23, 2015
    Publication date: July 16, 2015
    Inventors: NELSON NEAL STONE, E. DAVID CRAWFORD, WILLIAM L. NABORS, RICHARD B. RUSE, SR., SCOTT J. BOHANAN
  • Patent number: 8965527
    Abstract: A method and apparatus for treating masses, such as prostate or breast cancer, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a mass containing electrically-conductive ionic solutions so as to obtain 100% thermal beating or hyperthermia through the mass, and destroying it with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: February 24, 2015
    Assignee: Medamp Electronics, LLC
    Inventors: Richard B. Ruse, Scott J. Bohanan, E. David Crawford, William L. Nabors, Sr.
  • Publication number: 20140200574
    Abstract: A method and apparatus for treating masses, such as prostate or breast cancer, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a mass containing electrically-conductive ionic solutions so as to obtain 100% thermal beating or hyperthermia through the mass, and destroying it with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.
    Type: Application
    Filed: March 11, 2014
    Publication date: July 17, 2014
    Applicant: MEDAMP ELECTRONICS, LLC
    Inventors: RICHARD B. RUSE, SCOTT J. BOHANAN, E. DAVID CRAWFORD, WILLIAM L. NABORS, SR.
  • Patent number: 8706258
    Abstract: A method and apparatus for treating masses, such as prostate or breast cancer, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a mass containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the mass, and destroying it with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: April 22, 2014
    Assignee: MedAmp Electronics, LLC
    Inventors: William L. Nabors, Sr., Richard B. Ruse, Scott J. Bohanan, E. David Crawford
  • Patent number: 8406858
    Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation emission matrix is generated (1002). On-diagonal and off diagonal components of the excitation emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: March 26, 2013
    Assignee: The Regents of the University of Colorado, A Body Corporate
    Inventors: Priya N. Werahera, John Daily, M. Scott Lucia, Adrie van Bokhoven, E. David Crawford, Frank Barnes
  • Publication number: 20130041436
    Abstract: A method and apparatus for treating masses, such as prostate or breast cancer, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a mass containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the mass, and destroying it with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.
    Type: Application
    Filed: August 8, 2012
    Publication date: February 14, 2013
    Inventors: RICHARD B. RUSE, Scott J. Bohanan, E. David Crawford, Willam L. Nabors, SR.
  • Publication number: 20080194969
    Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation emission matrix is generated (1002). On-diagonal and off diagonal components of the excitation emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.
    Type: Application
    Filed: May 1, 2006
    Publication date: August 14, 2008
    Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO
    Inventors: Priya N. Werahera, John Daily, M. Scott Lucia, Adrie van Bokhoven, E. David Crawford, Frank Barnes