Patents by Inventor E. David Crawford
E. David Crawford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11737672Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation-emission matrix is generated (1002). On-diagonal and off-diagonal components of the excitation-emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation-emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.Type: GrantFiled: July 16, 2018Date of Patent: August 29, 2023Assignee: The Regents of the University of Colorado, A Body CorporateInventors: Priya N. Werahera, John Daily, M. Scott Lucia, Adrie van Bokhoven, E. David Crawford, Frank Barnes
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Publication number: 20230031498Abstract: A method and apparatus for treating bone or other infection in a patient to minimize the number of limb amputations which employs a unique, three-dimensional software-controlled electronic phased array amplifier system using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined infected area containing electrically-conductive ionic solutions so as to obtain 100% treatment using low or high voltage, low current that delivers electrical stimulation (ES) using a low DC current through and or around the defined infection treatment area. The minimally invasive treatment of the infection requires no radiation or chemotherapy that could be harmful to the patient.Type: ApplicationFiled: August 1, 2022Publication date: February 2, 2023Inventors: RICHARD B. RUSE, E. DAVID CRAWFORD, WILLIAM L. NABORS, SEAN BRUGMAN, SCOTT J. BOHANAN, PAUL ARANGUA
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Publication number: 20180360320Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation-emission matrix is generated (1002). On-diagonal and off-diagonal components of the excitation-emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation-emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.Type: ApplicationFiled: July 16, 2018Publication date: December 20, 2018Inventors: Priya N. Werahera, John Daily, M. Scott Lucia, Adrie van Bokhoven, E. David Crawford, Frank Barnes
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Patent number: 9486625Abstract: A method and apparatus for treating a condition in a patient such as BPH, irretractable infection, cyst, fibroid, or any mass such as prostate or breast cancer, skin cancer, melanoma, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined area containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the defined area. The condition is treated or a mass is destroyed with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.Type: GrantFiled: February 23, 2015Date of Patent: November 8, 2016Assignee: MedAmp Electronics, LLCInventors: E. David Crawford, William L. Nabors, Sr., Richard B. Ruse, Scott J. Bohanan
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Publication number: 20150196351Abstract: A method and apparatus for treating a condition in a patient such as BPH, irretractable infection, cyst, fibroid, or any mass such as prostate or breast cancer, skin cancer, melanoma, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined area containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the defined area. The condition is treated or a mass is destroyed with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.Type: ApplicationFiled: February 23, 2015Publication date: July 16, 2015Inventors: NELSON NEAL STONE, E. DAVID CRAWFORD, WILLIAM L. NABORS, RICHARD B. RUSE, SR., SCOTT J. BOHANAN
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Patent number: 8965527Abstract: A method and apparatus for treating masses, such as prostate or breast cancer, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a mass containing electrically-conductive ionic solutions so as to obtain 100% thermal beating or hyperthermia through the mass, and destroying it with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.Type: GrantFiled: March 11, 2014Date of Patent: February 24, 2015Assignee: Medamp Electronics, LLCInventors: Richard B. Ruse, Scott J. Bohanan, E. David Crawford, William L. Nabors, Sr.
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Publication number: 20140200574Abstract: A method and apparatus for treating masses, such as prostate or breast cancer, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a mass containing electrically-conductive ionic solutions so as to obtain 100% thermal beating or hyperthermia through the mass, and destroying it with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.Type: ApplicationFiled: March 11, 2014Publication date: July 17, 2014Applicant: MEDAMP ELECTRONICS, LLCInventors: RICHARD B. RUSE, SCOTT J. BOHANAN, E. DAVID CRAWFORD, WILLIAM L. NABORS, SR.
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Patent number: 8706258Abstract: A method and apparatus for treating masses, such as prostate or breast cancer, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a mass containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the mass, and destroying it with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.Type: GrantFiled: August 8, 2012Date of Patent: April 22, 2014Assignee: MedAmp Electronics, LLCInventors: William L. Nabors, Sr., Richard B. Ruse, Scott J. Bohanan, E. David Crawford
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Patent number: 8406858Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation emission matrix is generated (1002). On-diagonal and off diagonal components of the excitation emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.Type: GrantFiled: May 1, 2006Date of Patent: March 26, 2013Assignee: The Regents of the University of Colorado, A Body CorporateInventors: Priya N. Werahera, John Daily, M. Scott Lucia, Adrie van Bokhoven, E. David Crawford, Frank Barnes
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Publication number: 20130041436Abstract: A method and apparatus for treating masses, such as prostate or breast cancer, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a mass containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the mass, and destroying it with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.Type: ApplicationFiled: August 8, 2012Publication date: February 14, 2013Inventors: RICHARD B. RUSE, Scott J. Bohanan, E. David Crawford, Willam L. Nabors, SR.
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Publication number: 20080194969Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation emission matrix is generated (1002). On-diagonal and off diagonal components of the excitation emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.Type: ApplicationFiled: May 1, 2006Publication date: August 14, 2008Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADOInventors: Priya N. Werahera, John Daily, M. Scott Lucia, Adrie van Bokhoven, E. David Crawford, Frank Barnes