Patents by Inventor E. E. Atkinson, Jr.

E. E. Atkinson, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for recycling and regenerating carbonylation catalyst used in synthesis of ibuprofen
    Patent number: 5055611
    Abstract: A process for preparing ibuprofen is described. The improved process involves the treatment of spent palladium carbonylation catalyst with oxygen at about 300.degree. C. to about 850.degree. C. The treated material then used with a phosphine ligand to carbonylate 1-halo-1-(4-isobutyl-phenyl)ethane, 1-hydroxyl-1-(4-isobutylphenyl)ethane, or isobutylstyrene to produce ibuprofen.
    Type: Grant
    Filed: December 4, 1990
    Date of Patent: October 8, 1991
    Assignee: Ethyl Corporation
    Inventors: Ronny W. Lin, R. Carl Herndon, Jr., E. E. Atkinson, Jr.
  • Process for preparing ibuprofen and its alkyl esters
    Patent number: 4990658
    Abstract: A new process for preparing ibuprofen or its alkyl esters is provided. A 1-halo-1-(4-isobutylphenyl)ethane is reacted with carbon monoxide in the presence of water or an alcohol at a temperature between about 10.degree. C. and about 200.degree. C. An excess of several moles of water or alcohol is preferred. An acid such as hydrochloric acid may also be added. As catalyst, a palladium compound and at least one acid-stable ligand are present; however an excess of ligand over palladium is advantageous.
    Type: Grant
    Filed: December 18, 1989
    Date of Patent: February 5, 1991
    Assignee: Ethyl Corporation
    Inventors: Barbara C. Stahly, Ronny W. Lin, E. E. Atkinson, Jr.