Patents by Inventor E LIANG

E LIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLPRO PROTEIN INHIBITOR, AND PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20250289826
    Abstract: Disclosed in the present invention are a PLpro protease inhibitor, and a preparation method and application thereof. The PLpro protease inhibitor can be combined with one or more pharmaceutically acceptable auxiliary materials or one or more other active ingredients to serve as a PLpro inhibitor to treat diseases caused by or diseases related to virus infection. The auxiliary material can be a carrier, a diluent, an adhesive, a lubricant, a wetting agent, etc. The protease inhibitor has high inhibitory activity, and can be used for broad-spectrum antivirals, especially for coronaviruses, for example, HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU, SARS-CoV, MERS-CoV, SARS-CoV-2, etc., in particular SARS-CoV, MERS-CoV, SARS-CoV-2.
    Type: Application
    Filed: April 28, 2023
    Publication date: September 18, 2025
    Inventors: Wei HE, Cai WU, Bin LI, Haoxiang LI, Jiqing ZHENG, Shizhang WAN, Liqian XU, Meijing WANG, Kai LIU, Chenhao XU, E LIANG, Lei LIU
  • 2-(1H-pyrazol-3-yl) phenol compound and use thereof
    Patent number: 11332461
    Abstract: Provided are a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, ether, ester, prodrug and solvate thereof. The compound can be used for preventing and/or treating cancers.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: May 17, 2022
    Assignee: BEIJING JIALIN PHARMACEUTICAL INC.
    Inventors: Wei He, Xiaoding Hou, E Liang, Hongbo Li, Bin Li, Le Guo, Shuang Yang
  • 2-(1H-PYRAZOL-3-YL) PHENOL COMPOUND AND USE THEREOF
    Publication number: 20200354342
    Abstract: Provided are a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, ether, ester, prodrug and solvate thereof. The compound can be used for preventing and/or treating cancers.
    Type: Application
    Filed: October 22, 2018
    Publication date: November 12, 2020
    Applicant: BEIJING JIALIN PHARMACEUTICAL INC.
    Inventors: Wei HE, Xiaoding HOU, E LIANG, Hongbo LI, Bin LI, Le GUO, Shuang YANG