Patents by Inventor E. Tickner

E. Tickner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hollow microspheres with controlled fragility for medical use
    Publication number: 20070243138
    Abstract: A composition for ultrasonic imaging is described having a microparticle population of controlled fragility. A method of using such composition for imaging a fluid filled cavity, vessel or tissue is described.
    Type: Application
    Filed: August 17, 2004
    Publication date: October 18, 2007
    Inventors: Thomas Ottoboni, E. Tickner, Robert Short, Ronald Yamamoto
  • Hollow microspheres with controlled fragility for medical use
    Publication number: 20060241466
    Abstract: A composition for ultrasonic imaging is described having a microparticle population of controlled fragility. A method of using such composition for imaging a fluid filled cavity, vessel or tissue is described.
    Type: Application
    Filed: May 2, 2006
    Publication date: October 26, 2006
    Applicant: Point Biomedical Corporation
    Inventors: Thomas Ottoboni, E. Tickner, Robert Short, Ronald Yamamoto
  • Method for ultrasound triggered drug delivery using hollow microbubbles with controlled fragility
    Publication number: 20050283098
    Abstract: A method is provided for site specific delivering therapeutic or diagnostic agents to a region in a fluid-filled cavity, vessel or tissue using an agent-loaded microbubble population. The population has controlled fragility characterized by a uniform wall thickness to diameter ratio which defines the discrete threshold intensity value of ultrasonic power where microbubble rupture occurs in the population. The location of the microbubble population may be monitored by ultrasound to determine its presence at the region prior to application of the ultrasonic power to rupture to microbubbles.
    Type: Application
    Filed: April 14, 2005
    Publication date: December 22, 2005
    Inventors: Stanley Conston, Ronald Yamamoto, Thomas Ottoboni, E. Tickner
  • Hollow microspheres with controlled fragility for medical use
    Publication number: 20050013780
    Abstract: A composition for ultrasonic imaging is described having a microparticle population of controlled fragility. A method of using such composition for imaging a fluid filled cavity, vessel or tissue is described.
    Type: Application
    Filed: August 17, 2004
    Publication date: January 20, 2005
    Inventors: Thomas Otoboni, E. Tickner, Robert Short, Ronald Yamamoto