Patents by Inventor E. Yancey

E. Yancey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250115953
    Abstract: Provided are methylcytosine-selective deaminases, compositions, kits, and methods employing them, including a sequencing method involving (a) contacting a DNA substrate comprising cytosine (C) and at least one methylcytosine nucleobase selected from 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) or comprising C and both 5mC and 5hmC, with a methylcytosine-selective deaminase to produce a deamination product, wherein the methylcytosine-selective deaminase (i) is capable of deaminating 5mC to thymidine (T) and/or 5hmC to hydroxymethyluridine (hmU) and (ii) preferentially deaminates the at least one methylcytosine nucleobase relative to cytosine (C); and (b) sequencing the deamination product, or amplifying the deamination product to produce an amplification product, and sequencing the amplification product, in each case, to produce sequence reads, wherein positions of Cs and position of the at least one methylcytosine nucleobase in the DNA substrate is determined based on the sequence reads.
    Type: Application
    Filed: October 7, 2024
    Publication date: April 10, 2025
    Applicant: New England Biolabs, Inc.
    Inventors: Laurence Ettwiller, Peter R. Weigele, Yan-Jiun Lee, Weiwei Yang, Amanda N. Deliberto, Rebekah M. B. Silva, Sean R. Johnson, Colleen E. Yancey
  • Patent number: 9458345
    Abstract: The present invention includes coating compositions and methods for coating substrates using the coating compositions. In some embodiments of the invention, a coating composition is prepared by a method including the steps of a) preparing a latex emulsion by a method including mixing an ethylenically unsaturated monomer component in a carrier to form a monomer emulsion, and reacting the monomer emulsion with an initiator to form the latex emulsion, b) preparing a hydroxyl functional oil graft copolymer by a method including reacting an epoxidized vegetable oil with a hydroxyl functional material in the presence of an acid catalyst to form a hydroxyl functional oil polyol, and reacting the hydroxyl functional oil polyol with an ethylenically unsaturated monomer component in the presence of an initiator to form the hydroxyl functional oil polyol graft copolymer, and c) blending the latex emulsion and a crosslinker then adding the hydroxyl functional oil graft copolymer to form the coating composition.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: October 4, 2016
    Assignee: AKZO NOBEL COATINGS INTERNATIONAL B.V.
    Inventors: David James Telford, Kenneth James Gardner, Ryan Roberts, Sr., Tiffany Weidendorf, Denise E. Yancey
  • Publication number: 20130280454
    Abstract: The present invention includes coating compositions and methods for coating substrates using the coating compositions. In some embodiments of the invention, a coating composition is prepared by a method including the steps of a) preparing a latex emulsion by a method including mixing an ethylenically unsaturated monomer component in a carrier to form a monomer emulsion, and reacting the monomer emulsion with an initiator to form the latex emulsion, b) preparing a hydroxyl functional oil graft copolymer by a method including reacting an epoxidized vegetable oil with a hydroxyl functional material in the presence of an acid catalyst to form a hydroxyl functional oil polyol, and reacting the hydroxyl functional oil polyol with an ethylenically unsaturated monomer component in the presence of an initiator to form the hydroxyl functional oil polyol graft copolymer, and c) blending the latex emulsion and a crosslinker then adding the hydroxyl functional oil graft copolymer to form the coating composition.
    Type: Application
    Filed: December 28, 2011
    Publication date: October 24, 2013
    Inventors: David James Telford, Kenneth James Gardner, Ryan Roberts, SR., Tiffany Weidendorf, Denise E. Yancey
  • Publication number: 20050153132
    Abstract: A high strength wick is presented that comprises a self-sustaining fibrous element. This element is formed of a multiplicity of fibers bonded to each other at spaced apart points of contact to define a porous matrix. The fibers are melt blown bicomponent fibers comprising a core of nylon 6,6 and a sheath of a polymer selected from the group consisting of polyethylene terephthalate and copolymers of polyethylene terephthalate. The sheath polymer is selected and adapted for solvent resistance.
    Type: Application
    Filed: January 7, 2005
    Publication date: July 14, 2005
    Applicant: Filtrona Richmond, Inc.
    Inventors: Bennett Ward, Robert Long, Donald Nelson, Raymond Nelson, Jackie Payne, E. Yancey
  • Patent number: 5729451
    Abstract: A data fusion workstation apparatus and method utilizes algorithms and can be used for applications such as, e.g., hydrogeological modeling, steady-state hydrological flow modeling, transport uncertainty determination, flow/transport fusion, oil reserve management, water supply development, geo-technical engineering projects, and management decision optimization. The invention uses a spatial continuity model which is extended to 3D and equations are provided for computation of the spatial AR coefficients from a desired covariance function. The data fusion workstation provides more robust optimization iterations by use of an algorithm that includes Trust Region or Step Halving methods to limit the Gauss Newton step in solving non-linear least squares problems. Measurement biases and error parameters, and parameters which define a hydrological flow model can be included in the common set of estimated states.
    Type: Grant
    Filed: December 1, 1995
    Date of Patent: March 17, 1998
    Assignee: Coleman Research Corporation
    Inventors: Bruce P. Gibbs, David W. Porter, William E. Yancey
  • Patent number: 5290828
    Abstract: An aqueous dispersed, low VOC coating containing a polymeric binder comprises an addition copolymer grafted epoxy polyester terpolymer. The graft terpolymer comprises by weight between 1% and 70% unsaturated polyester, 5% and 80% epoxy resin, and 5% and 70% addition copolymer, where the terpolymer has an Acid Number above about 30 and is dispersed into water with a volatile base.
    Type: Grant
    Filed: June 11, 1993
    Date of Patent: March 1, 1994
    Assignee: The Glidden Company
    Inventors: Gary P. Craun, Daniel Bode, Denise E. Yancey
  • Patent number: 5046729
    Abstract: The apparatus of the invention comprises a backboard; a matrix of panels representing a strike zone; springs for resiliently biasing each of the panels outwardly from the backboard; switches mounted to the backboard behind the panels, whereby the impact of a pitched ball will move the panel inwardly towards the backboard causing the switch to momentarily close; a horizontal array of red, yellow and green lamps mounted to the backboard adjacent the top of the backboard, one lamp in vertical alignment with each of the columns of panels; a left vertical array of red, yellow and green lamps mounted to the backboard adjacent the left edge of the backboard, one lamp in horizontal alignment with each row of panels; a right vertical array of red, yellow and green lamps mounted to the backboard adjacent the right edge of the backboard, a power source; and electrical wiring to connect the power source, switches and lamps.
    Type: Grant
    Filed: September 12, 1990
    Date of Patent: September 10, 1991
    Inventor: William E. Yancey
  • Patent number: 4585545
    Abstract: An aromatic gasoline component is prepared in a multi-step petroleum refining process starting with a heavy carbometallic petroleum fraction which is catalytically cracked to yield a light catalytic cycle oil which, in turn, is mildly hydrogenated to produce a partially saturated bicyclic hydrocarbon fraction which itself is catalytically cracked to yield a monoaromatic hydrocarbon fraction from which is recovered a gasoline product. The bicyclic hydrocarbons are converted to monoaromatics by selective partial saturation and ring scission.
    Type: Grant
    Filed: December 7, 1984
    Date of Patent: April 29, 1986
    Assignee: Ashland Oil, Inc.
    Inventors: Robert E. Yancey, Jr., William P. Hettinger, Jr.