Abstract: Embodiments of the present disclosure provide systems and methods for implementing self-bias detection based on performance and importance. A disclosed computer implemented method aggregates continuous input data through a K-means clustering algorithm to reduce the number of aggregated sub-group data pairs, enabling a reduced calculation time for computing bias and enhanced performance. The self-bias detection identifies a scale factor and a balance factor of aggregated sub-group data pairs, which indicate the importance of the detected bias.

Abstract: Embodiments of the present disclosure provide systems and methods for implementing self-bias detection based on performance and importance. A disclosed computer implemented method aggregates continuous input data through a K-means clustering algorithm to reduce the number of aggregated sub-group data pairs, enabling a reduced calculation time for computing bias and enhanced performance. The self-bias detection identifies a scale factor and a balance factor of aggregated sub-group data pairs, which indicate the importance of the detected bias.

Abstract: Provided is a method for determining an evolutionary primitive ancestry of Goji berry and use thereof, which relate to the field of species origin and genetic evolution. The method for determining an evolutionary primitive ancestry of Goji berry includes developing genome-wide molecular markers of Goji berries based on Specific-Locus Amplified Fragment Sequencing (SLAF-seq) technology, and determining the primitive ancestry of Goji berry through bioinformatic analysis. The selected Goji berries include not only wild Goji berries from Ningxia, Gansu, Qinghai, Xinjiang, Shaanxi, Inner Mongolia and Henan, but also Korean and Mexican Goji berry germplasms, with a wide range of sample sources, strong representation and large amount of information. The original ancestral genetic taxa of each Goji berry can be accurately determined through big data analysis. The gap in the origin and genetic evolution of Goji berry is thus fulfilled. The method has a good prospect in application.

Abstract: Disclosed herein are methods, kits, systems, algorithms and improvements for detecting the presence of or determining an amount, quantity, concentration and/or level of an antibody against at least one type of ?-coronavirus, such as, for example, an antibody against SARS-CoV or SARS-CoV-2, in one or more samples obtained from a subject. In some aspects, the methods, kits and systems relate to detecting the presence of or determining an amount, quantity, concentration and/or level of at least one type of anti-?-coronavirus antibody, such as an IgG and/or IgM antibody, in one or more samples obtained from a subject.

Abstract: A frame is provided, for applying potting material to a printed circuit board (PCB). The frame includes a plurality of substantially vertically oriented walls arranged to isolate a surface of the PCB into a plurality of zones. This allows the frame to be aligned over the surface of the PCB to isolate the surface of the PCB into a plurality of zones, each zone comprising at least one PCB component; and allows the potting material to be applied into the zones to achieve coverage of the PCB components in that zone.

Abstract: The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.

Abstract: A method and system for handing off a terminal among a plurality of wireless access points (APs) connected to a central management AP. The method comprising: receiving network condition information of a terminal communicatively connected to a first wireless AP among the plurality of wireless APs. Determining a second wireless AP the plurality of wireless APs to which the terminal is to be handed off based on the network condition information of the terminal. The second wireless AP is virtually connected to the terminal. Submitting a handoff request to the second wireless AP. Notifying the terminal to hand off to the second wireless AP in response to receiving a handoff response from the second wireless AP.

Abstract: The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.

Abstract: A method and system for handing off a terminal among a plurality of wireless access points (APs) connected to a central management AP. The method comprising: receiving network condition information of a terminal communicatively connected to a first wireless AP among the plurality of wireless APs. Determining a second wireless AP the plurality of wireless APs to which the terminal is to be handed off based on the network condition information of the terminal. The second wireless AP is virtually connected to the terminal. Submitting a handoff request to the second wireless AP. Notifying the terminal to hand off to the second wireless AP in response to receiving a handoff response from the second wireless AP.

Abstract: A method and system for handing off a terminal among a plurality of wireless access points (APs) connected to a central management AP. The method comprising: receiving network condition information of a terminal communicatively connected to a first wireless AP among the plurality of wireless APs. Determining a second wireless AP the plurality of wireless APs to which the terminal is to be handed off based on the network condition information of the terminal. The second wireless AP is virtually connected to the terminal. Submitting a handoff request to the second wireless AP. Notifying the terminal to hand off to the second wireless AP in response to receiving a handoff response from the second wireless AP.

Abstract: The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.

Abstract: A method and system for handing off a terminal among a plurality of wireless access points (APs) connected to a central management AP. The method comprising: receiving network condition information of a terminal communicatively connected to a first wireless AP among the plurality of wireless APs. Determining a second wireless AP the plurality of wireless APs to which the terminal is to be handed off based on the network condition information of the terminal. The second wireless AP is virtually connected to the terminal. Submitting a handoff request to the second wireless AP. Notifying the terminal to hand off to the second wireless AP in response to receiving a handoff response from the second wireless AP.

Abstract: The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.

Abstract: Provided herein are non-peptide GLP-1 receptor modulator compounds, for example, of Formula I, pharmaceutical compositions comprising such compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of a metabolic disorder.

Abstract: The present invention provides a resin composition consisting of a functionalized polypropylene (PP) and a functionalized styrenic thermoplastic elastomer (TPS). The functionalized PP is a PP grafted with N-vinyl pyrrolidone (NVP) and glycidyl methacrylate (GMA), and the functionalized TPS is a TPS grafted with acrylamide or methacrylamide. The functionalized PP and the functionalized TPS are subjected to melt blending to obtain the resin composition with a slight cross-linking structure due to the reaction between GMA and acrylamide or methacrylamide, therefore the resin composition presents good physical properties. Besides, the resin composition without additional plasticizer or other small molecular organic compounds can be utilized in blood bags, blood transfusion and collection apparatuses, etc. Thus, it does not release small molecular substances which are of potential harm to human body during use.

Abstract: Provided herein are non-peptide GLP-1 receptor modulator compounds, for example, of Formula I, pharmaceutical compositions comprising such compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of a metabolic disorder.

Abstract: The present invention provides a resin composition consisting of a functionalized polypropylene (PP) and a functionalized styrenic thermoplastic elastomer (TPS). The functionalized PP is a PP grafted with N-vinyl pyrrolidone (NVP) and glycidyl methacrylate (GMA), and the functionalized TPS is a TPS grafted with acrylamide or methacrylamide. The functionalized PP and the functionalized TPS are subjected to melt blending to obtain the resin composition with a slight cross-linking structure due to the reaction between GMA and acrylamide or methacrylamide, therefore the resin composition presents good physical properties. Besides, the resin composition without additional plasticizer or other small molecular organic compounds can be utilized in blood bags, blood transfusion and collection apparatuses, etc. Thus, it does not release small molecular substances which are of potential harm to human body during use.

Abstract: Metabolites of a matrix metalloproteinase inhibitor prinomastat and their synthesis. These metabolites are: (3S)-N-hydroxy-4-(4-((1-oxy-pyrid-4-yl)oxy)benzenesulfonyl)-2,2-dimethyl-tetrahydro-2H-1,4-thiazine-3-carboxamide (M6); (3S)-2,2-dimethyl-1,1-dioxo-4-[4-(1-oxy-pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid amide (M7); (3S)-2,2-dimethyl-4-[4-(1-oxypyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid amide (M8); (3S)-2,2-dimethyl-1,1-dioxo-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid amide (M2); and (3S)-2,2-dimethyl-4-[4-(pyridin-4yloxy)-benzenesulfonyl)-thiomorphpline-3-carboxylic acid amide (M3).