Patents by Inventor Earl Brown

Earl Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection, characterization and treatment of viral infection and methods thereof
    Patent number: 7572621
    Abstract: A method of detecting, characterizing and treating viral infection is provided. In particular, a strategy of molecular mimicry is provided for characterizing viral behavior and/or a predisposition for a given viral outcome in vivo. Novel compositions are also provided for detecting, characterizing and treating viral infections.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: August 11, 2009
    Assignee: Canadian Blood Services
    Inventors: Yu-wen Hu, Earl Brown
  • ONCOLYTIC VIRUS
    Publication number: 20070166287
    Abstract: The present invention is directed to a method of reducing the viability of a tumor cell involving administering a virus that is not a common human pathogen to the tumor cell. Preferably, the virus exhibits differential susceptibility, in that normal cells are not affected by the virus. This differential susceptibility is more pronounced in the presence of interferon. The tumor cell is characterized by having low levels, or no, PKR activity, or as being PKR?/?, STAT1?/? or both PKR?/? and STAT1?/?. The virus is selected from the group consisting of Rhabdovirus and picomavirus, and preferably is vesicular stomatitis virus (VSV) or a derivative thereof.
    Type: Application
    Filed: March 13, 2007
    Publication date: July 19, 2007
    Applicant: WELLSTAT BIOLOGICS CORPORATION
    Inventors: John Bell, Nahum Sonenberg, David Stojdl, Earl Brown, Harold Atkins, Ricardo Marius, Brian Lichty, Shane Knowles
  • Detection, characterization and treatment of viral infection and methods thereof
    Publication number: 20060115875
    Abstract: A method of detecting, characterizing and treating viral infection is provided. In particular, a strategy of molecular mimicry is provided for characterizing viral behavior and/or a predisposition for a given viral outcome in vivo. Novel compositions are also provided for detecting, characterizing and treating viral infections.
    Type: Application
    Filed: October 11, 2005
    Publication date: June 1, 2006
    Inventors: Yu-wen Hu, Earl Brown