Patents by Inventor Earl J. Gubbins

Earl J. Gubbins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cholinergic/serotoninergic receptor and uses thereof
    Patent number: 8759504
    Abstract: The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of ?7 nicotinic acetylcholine receptors.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: June 24, 2014
    Assignee: AbbVie Inc.
    Inventors: Murali Gopalakrishnan, Jinhe Li, Steven C. Cassar, John Malysz, David J. Anderson, Earl J. Gubbins, Daniel C. Bertrand
  • Pyrrole derivatives and their methods of use
    Patent number: 8609713
    Abstract: The invention relates to a series of substituted pyrrole derivatives, compositions comprising the same, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: December 17, 2013
    Assignee: AbbVie Inc.
    Inventors: Ramin Faghih, Gregory A. Gfesser, Christopher L. Lynch, Murali Gopalakrishnan, Sujatha Gopalakrishnan, John Malysz, Earl J. Gubbins, Rachid El Kouhen, Jinhe Li
  • Thiazoline and oxazoline derivatives and their methods of use
    Patent number: 8470813
    Abstract: The invention relates to a series of thiazoline and oxazoline derivatives, compositions thereof, and methods of treating conditions and disorders using such compounds.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: June 25, 2013
    Assignee: AbbVie Inc.
    Inventors: Ramin Faghih, Gregory A. Gfesser, Christopher L. Lynch, Murali Gopalakrishnan, Sujatha Gopalakrishnan, John Malysz, Earl J. Gubbins, Rachid El Kouhen, Jinhe Li, Kathy A. Sarris, Melissa J. Michmerhuizen, Ying Wang
  • CHOLINERGIC/SEROTONINERGIC RECEPTOR AND USES THEREOF
    Publication number: 20120219967
    Abstract: The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of ?7 nicotinic acetylcholine receptors.
    Type: Application
    Filed: February 6, 2012
    Publication date: August 30, 2012
    Inventors: Murali Gopalakrishnan, Jinhe Li, Steven C. Cassar, John Malysz, David J. Anderson, Earl J. Gubbins, Daniel C. Bertrand
  • Large area, homogeneous array fabrication including homogeneous substrates
    Publication number: 20100221505
    Abstract: An article comprising: at least one solid substrate comprising at least one surface providing a surface area of at least one square millimeter, wherein the surface comprises a homogeneous array of material deposits which covers at least 90% of the surface area. Edge-to-edge patterning and large area substrates can be achieved. Applications include growth of cells.
    Type: Application
    Filed: January 25, 2010
    Publication date: September 2, 2010
    Inventors: Nabil A. Amro, Raymond Sanedrin, Earl J. Gubbins
  • Pyrrole Derivatives and Their Methods of Use
    Publication number: 20100216748
    Abstract: The invention relates to a series of substituted pyrrole derivatives, compositions comprising the same, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 7, 2010
    Publication date: August 26, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Ramin Faghih, Gregory A. Gfesser, Christopher L. Lynch, Murali Gopalakrishnan, Sujatha Gopalakrishnan, John Malysz, Earl J. Gubbins, Rachid El Kouhen, Jinhe Li
  • Thiazoline and Oxazoline Derivatives and Their Methods of Use
    Publication number: 20100190776
    Abstract: The invention relates to a series of thiazoline and oxazoline derivatives, compositions thereof, and methods of treating conditions and disorders using such compounds.
    Type: Application
    Filed: January 28, 2010
    Publication date: July 29, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Ramin Faghih, Gregory A. Gfesser, Christopher L. Lynch, Murali Gopalakrishnan, Sujatha Gopalakrishnan, John Malysz, Earl J. Gubbins, Rachid El Kouhen, Jinhe Li, Kathy A. Sarris, Melissa J. Michmerhuizen, Ying Wang
  • Pyrrole derivatives and their methods of use
    Patent number: 7741364
    Abstract: The invention relates to a series of substituted pyrrole derivatives, compositions comprising the same, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: June 22, 2010
    Assignee: Abbott Laboratories
    Inventors: Ramin Faghih, Gregory A. Gfesser, Christopher L. Lynch, Murali Gopalakrishnan, Sujatha Gopalakrishnan, John Malysz, Earl J. Gubbins, Rachid El Kouhen, Jinhe Li
  • Thiazoline and oxazoline derivatives and their methods of use
    Patent number: 7683084
    Abstract: The invention relates to a series of thiazoline and oxazoline derivatives, compositions thereof, and methods of treating conditions and disorders using such compounds.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: March 23, 2010
    Assignee: Abbott Laboratories
    Inventors: Ramin Faghih, Gregory A. Gfesser, Christopher L. Lynch, Murali Gopalakrishnan, Sujatha Gopalakrishnan, John Malysz, Earl J. Gubbins, Rachid El Kouhen, Jinhe Li, Kathy A. Sarris, Melissa J. Michmerhuizen, Ying Wang
  • CHOLINERGIC/SEROTONINERGIC RECEPTOR AND USES THEREOF
    Publication number: 20090123945
    Abstract: The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of ?7 nicotinic acetylcholine receptors.
    Type: Application
    Filed: June 25, 2008
    Publication date: May 14, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Murali Gopalakrishnan, Jinhe Li, Steven C. Cassar, John Malysz, David J. Anderson, Earl J. Gubbins, Daniel C. Bertrand
  • Antiangiogenic peptides, polypeptides encoding same and methods for inhibiting angiogenesis
    Patent number: 7495068
    Abstract: Mammalian kringle 5 fragments and kringle 5 fusion proteins are disclosed as a compounds for treating angiogenic diseases. Methods and compositions for inhibiting angiogenic diseases are also disclosed.
    Type: Grant
    Filed: January 8, 2004
    Date of Patent: February 24, 2009
    Assignee: Abbott Laboratories
    Inventors: Donald J. Davidson, Jieyi Wang, Earl J. Gubbins
  • Novel antiangiogenic peptides, polypeptides encoding same and methods for inhibiting angiogenesis
    Publication number: 20040138127
    Abstract: Mammalian kringle 5 fragments and kringle 5 fusion proteins are disclosed as a compounds for treating angiogenic diseases. Methods and compositions for inhibiting angiogenic diseases are also disclosed.
    Type: Application
    Filed: January 8, 2004
    Publication date: July 15, 2004
    Inventors: Donald J. Davidson, Jieyi Wang, Earl J. Gubbins
  • AZOLE INHIBITORS OF CYTOKINE PRODUCTION
    Publication number: 20010044445
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: April 8, 1999
    Publication date: November 22, 2001
    Inventors: NWE Y. BAMAUNG, ANWER BASHA, STEVAN W. DJURIC, EARL J. GUBBINS, JAY R. LULY, NOAH P. TU, DAVID J. MADAR, USHA WARRIOR, PAUL E. WIEDEMAN, XUN ZHOU, RICHARD J. SCIOTTI, FRANK L. WAGENAAR