Patents by Inventor Earl M. Gibbs

Earl M. Gibbs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphodiesterase 10 Inhibition as Treatment for Obesity-Related and Metabolic Syndrome-Related Conditions
    Publication number: 20090162286
    Abstract: The present invention provides methods to decrease body weight and/or body fat in animals, e.g., in the treatment of overweight or obese patients (e.g., humans or companion animals), or as a means to produce leaner meat in food stock animals (e.g., cattle, chickens, pigs), methods to treat non-insulin dependent diabetes (NIDDM), metabolic syndrome, or glucose intolerance, in patients in need thereof by administering a PDE10 inhibitor (alone or in combination with another therapeutic agent), kits for the above-identified therapeutic uses, and methods of identifying PDE10 inhibitors for the above-described therapeutic uses.
    Type: Application
    Filed: May 30, 2005
    Publication date: June 25, 2009
    Inventors: Shawn C. Black, Earl M. Gibbs
  • Phosphodiesterase 9 Inhibition as Treatment for Obesity-Related Conditions
    Publication number: 20080282364
    Abstract: The present invention is directed to methods to decrease body weight and/or body fat in an animal, e.g., in the treatment of overweight or obese patients (e.g., humans or companion animals), or as a means to produce leaner meat in food stock animals (e.g., cattle, chickens, pigs), and methods to treat eating disorders (e.g., binge eating disorder and bulimia) in patients in need thereof by administering a PDE9 inhibitor. The invention also features biological tools to further study PDE9 function, i.e., genetically-modified mice and animal cells having a PDE9 gene disruption.
    Type: Application
    Filed: October 18, 2004
    Publication date: November 13, 2008
    Inventors: Shawn C Black, Earl M Gibbs, John D McNeish
  • Treatment of diabetes mellitus
    Patent number: 6683080
    Abstract: Use of vardenafil or a pharmaceutical composition thereof in the preparation of a medicament for the curative, palliative or prophylactic treatment of type 2 diabetes mellitus.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: January 27, 2004
    Assignee: Pfizer Inc.
    Inventors: David A. Fryburg, Earl M. Gibbs, Nandan P. Koppiker
  • Treatment of diabetes mellitus
    Publication number: 20020143015
    Abstract: Use of vardenafil or a pharmaceutical composition thereof in the preparation of a medicament for the curative, palliative or prophylactic treatment of type 2 diabetes mellitus.
    Type: Application
    Filed: January 30, 2002
    Publication date: October 3, 2002
    Inventors: David A. Fryburg, Earl M. Gibbs, Nandan P. Koppiker