Abstract: Article and means for a hybrid transit vehicle, transit system and assemblage thereof. Vehicle composition may include at least one chassis frame arrangement for a pivoting articulating suspension to position wheel axle to “X” horizontal axis for vehicle modality by wheel contact to ground-based surface and to position wheel axle to “Z” vertical axis for vehicle modality by wheel and utility contact to surface of rail guideway.

Abstract: Provided is a process including: obtaining, with a network controls engine, network traffic, wherein: the network traffic is sent across the network between source computing devices and destination computing devices; at least one of the source or destination computing devices are on a network carrying the network traffic; and the network has a plurality of computing devices causing the network traffic and which are assigned addresses on the network; applying, with the network controls engine, a plurality of rules to the network traffic to identify rules with criteria satisfied by the network traffic; and causing, with the network controls engine, one or more actions prescribed by one or more identified rules with criteria satisfied by the network traffic.

Abstract: Provided is a process including: obtaining, with a network controls engine, network traffic, wherein: the network traffic is sent across the network between source computing devices and destination computing devices; at least one of the source or destination computing devices are on a network carrying the network traffic; and the network has a plurality of computing devices causing the network traffic and which are assigned addresses on the network; applying, with the network controls engine, a plurality of rules to the network traffic to identify rules with criteria satisfied by the network traffic; and causing, with the network controls engine, one or more actions prescribed by one or more identified rules with criteria satisfied by the network traffic.

Abstract: Provided is a process including: obtaining, with a network controls engine, network traffic, wherein: the network traffic is sent across the network between source computing devices and destination computing devices; at least one of the source or destination computing devices are on a network carrying the network traffic; and the network has a plurality of computing devices causing the network traffic and which are assigned addresses on the network; applying, with the network controls engine, a plurality of rules to the network traffic to identify rules with criteria satisfied by the network traffic; and causing, with the network controls engine, one or more actions prescribed by one or more identified rules with criteria satisfied by the network traffic.

Abstract: Provided is a private and secure network that uses an authentication mechanism with a uniquely assigned private IP address and network credentials issued as part of a VPN certificate exchange. A first layer of authentication establishes a secure tunnel between user and VPN server, and a second layer of authentication connects that secure tunnel to the web site or resource, without passing the VPN certificate. Once authenticated, interaction between website or resource and user are automatically monitored for abnormal or malicious behavior and, if required, automatic verification and authentication response is generated.

Abstract: Provided is a private and secure network that uses an authentication mechanism with a uniquely assigned private IP address and network credentials issued as part of a VPN certificate exchange. A first layer of authentication establishes a secure tunnel between user and VPN server, and a second layer of authentication connects that secure tunnel to the web site or resource, without passing the VPN certificate. Once authenticated, interaction between website or resource and user are automatically monitored for abnormal or malicious behavior and, if required, automatic verification and authentication response is generated.

Abstract: Provided is a process including: obtaining, with a network controls engine, network traffic, wherein: the network traffic is sent across the network between source computing devices and destination computing devices; at least one of the source or destination computing devices are on a network carrying the network traffic; and the network has a plurality of computing devices causing the network traffic and which are assigned addresses on the network; applying, with the network controls engine, a plurality of rules to the network traffic to identify rules with criteria satisfied by the network traffic; and causing, with the network controls engine, one or more actions prescribed by one or more identified rules with criteria satisfied by the network traffic.

Abstract: Provided is a process including: obtaining, with a network controller, a current state of a network; causing, with the network controller, a graphical user interface to be presented that depicts at least part of the network graph and includes user-inputs by which a user requests changes to the network graph; receiving, with the network controller, a request input to modify the network graph; and modifying, with the network controller, the network graph and enforcing the modification.

Abstract: Provided is a process including: obtaining, with a network controls engine, network traffic, wherein: the network traffic is sent across the network between source computing devices and destination computing devices; at least one of the source or destination computing devices are on a network carrying the network traffic; and the network has a plurality of computing devices causing the network traffic and which are assigned addresses on the network; applying, with the network controls engine, a plurality of rules to the network traffic to identify rules with criteria satisfied by the network traffic; and causing, with the network controls engine, one or more actions prescribed by one or more identified rules with criteria satisfied by the network traffic.

Abstract: Provided is a process including: obtaining, with a network controls engine, network traffic, wherein: the network traffic is sent across the network between source computing devices and destination computing devices; at least one of the source or destination computing devices are on a network carrying the network traffic; and the network has a plurality of computing devices causing the network traffic and which are assigned addresses on the network; applying, with the network controls engine, a plurality of rules to the network traffic to identify rules with criteria satisfied by the network traffic; and causing, with the network controls engine, one or more actions prescribed by one or more identified rules with criteria satisfied by the network traffic.

Abstract: Provided is a process including: obtaining, with a network controller, a current state of a network; causing, with the network controller, a graphical user interface to be presented that depicts at least part of the network graph and includes user-inputs by which a user requests changes to the network graph; receiving, with the network controller, a request input to modify the network graph; and modifying, with the network controller, the network graph and enforcing the modification.

Abstract: In general, among other things, compounds of Formula I are provided: or a pharmaceutically acceptable salt thereof, in which R1-7, 9-10 are each independently selected from the group consisting of hydrogen, hydroxy, alkoxy, and alkyl; and R8 is selected from the group consisting of fluoro, iodo, and tributyltin. Other compounds are also provided. Methods of treatment and diagnosis are also provided.

Abstract: Compounds useful for the early diagnosis of malignant tumors, multiple sclerosis, and especially Alzheimer's Disease and related dementias; especially compounds of Formula (I) wherein R1 is selected from the group consisting of hydrogen, cyano, fluoro, iodo, alkyl, and aryl; R2 is selected from the group consisting of hydrogen, alkyl, and aryl; X is selected from the group consisting of CH2, CH2O, oxygen, OCH2, CH2S, SCH2, NH, N-alkyl, and N-aryl; Y is an optional spacer group, absent or selected from the group consisting of oxygen, sulfur, NH, N-alkyl, and N-aryl; and Z is selected from the group consisting of alkyl substituted with cyano, fluoro, or iodo and aryl substituted with cyano, fluoro, or iodo. In a preferred embodiment, R1 and R2 are hydrogen, X is CH2O, Y is absent, and Z is phenyl substituted with fluoro, cyano, or iodo. In some embodiments, Z is more specifically 18F-phenyl or 123I-phenyl or 131I-phenyl. Other compounds are also provided.

Abstract: Compounds useful for the early diagnosis of malignant tumors, multiple sclerosis, and especially Alzheimer's Disease and related dementias; especially compounds of Formula (I) wherein R1 is selected from the group consisting of hydrogen, cyano, fluoro, iodo, alkyl, and aryl; R2 is selected from the group consisting of hydrogen, alkyl, and aryl; X is selected from the group consisting of CH2, CH2O, oxygen, OCH2, CH2S, SCH2, NH, N-alkyl, and N-aryl; Y is an optional spacer group, absent or selected from the group consisting of oxygen, sulfur, NH, N-alkyl, and N-aryl; and Z is selected from the group consisting of alkyl substituted with cyano, fluoro, or iodo and aryl substituted with cyano, fluoro, or iodo. In a preferred embodiment, R1 and R2 are hydrogen, X is CH2O, Y is absent, and Z is phenyl substituted with fluoro, cyano, or iodo. In some embodiments, Z is more specifically 18F-phenyl or 123I-phenyl or 131I-phenyl. Other compounds are also provided.

Abstract: This invention relates to a compound of formula I: or a pharmaceutically acceptable salt thereof; in which preferably R3, R4 and R6 are each hydrogen; X is C═O or CH2; and R7 and R8 are each independently selected from the group consisting of hydrogen, (C1-C12)alkyl, (C3-C8)cycloalkyl and (C1-C12)alkyl (C6-C14)aryl; or R7 and R8 when taken together form a (C2-C7)alkylene group; or —NR7R8 together forms a (C2-C14)heterocyclic or substituted (C2-C14)heterocyclic. Such compounds modulate the activity of serine hydrolases and can be used in pharmaceutical compositions for the treatment of Alzheimer's disease.

Abstract: Methods and systems are provided for use in enhancing interactive presentations. Access is gained to a computer-based presentation that is presentable by conventional desktop presentation software, and a feature is added to the computer-based presentation. An aspect of the feature may be presentable by the conventional desktop presentation software. Using Internet-standard protocols, a real-time directive is issued to a playback device based on the feature and a response to the directive is received. A real time analysis of results of issuing the directive may be provided based at least in part on the response.

Abstract: This invention relates to a compound of formula I: or a pharmaceutically acceptable salt thereof; in which preferably R3, R4 and R6 are each hydrogen; X is C═O or CH2; and R7 and R8 are each independently selected from the group consisting of hydrogen, (C1-C12)alkyl, (C3-C8)cycloalkyl and (C1-C12)alkyl(C6-C14)aryl; or R7 and R8 when taken together form a (C2-C7)alkylene group; or —NR7R8 together forms a (C2-C14)heterocyclic or substituted (C2-C14)heterocyclic. Such compounds modulate the activity of serine hydrolases and can be used in pharmaceutical compositions for the treatment of Alzheimer's disease.

Abstract: This invention relates to a compound of formula I: 1

Abstract: A tabletop assembly (20) for securing articles against high acceleration loads includes a substantially planar tabletop (22) having a top surface (24) and an opposite bottom surface (26). At least one article-receiving track (28) is inset into the top of tabletop (22). A brace (36) is disposed beneath the tabletop (22) and connected to the track (28) so that the track (28) will not separate from the tabletop (22) under high acceleration loads such as from a seismic event.