Patents by Inventor Earl R. Kern

Earl R. Kern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treatment with compositions effective against acyclovir-resistant strains of herpes viruses
    Patent number: 6040298
    Abstract: The present invention relates to pharmaceutical compositions useful for the treatment of subjects suffering from an infection or disease caused by herpes virus strains that are resistant to treatment with acyclovir. In particular, it has been discovered that the low dosage amounts of 1-(2'-deoxy-2'-fluoro-.beta.-D-arabinofuranosyl)-5-iodouracil (FIAU) are effective in inhibiting replication of acyclovir-resistant HSV strains. The present invention is also directed to methods of the preparation of pharmaceutical antiviral compositions and to the methods of their use in the treatment of infection or disease.
    Type: Grant
    Filed: December 23, 1992
    Date of Patent: March 21, 2000
    Assignee: Oclassen Pharmaceuticals, Inc.
    Inventors: Dennis W. Adair, Karl M. Johnson, Earl R. Kern