Patents by Inventor Earle Holsapple

Earle Holsapple has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for combined diagnostic and therapeutic ultrasound system incorporating noninvasive thermometry, ablation control and automation
    Patent number: 8376946
    Abstract: A method for treating a medical pathology includes receiving a first set of acoustic radiation scattered by a volume of tissue containing at least a portion of the medical pathology and thereafter, changing a temperature of the volume of tissue. The method also includes thereafter, receiving a second set of acoustic radiation scattered by the volume of tissue and localizing the portion of the medical pathology from the first and second sets of received acoustic radiation. Localizing the portion of the medical pathology comprises identifying the medical pathology from differences in the first and second sets of received acoustic radiation resulting from the change in temperature. The method also includes insonifying the portion of the medical pathology with sufficient energy to damage the portion of the medical pathology.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: February 19, 2013
    Assignee: Barbara Ann Karamanos Cancer Institute
    Inventors: Peter J. Littrup, Nebojsa Duric, Earle Holsapple, III
  • Computerized ultrasound risk evaluation system
    Patent number: 7285092
    Abstract: A method and system for examining tissue are provided in which the tissue is maintained in a position so that it may be insonified with a plurality of pulsed spherical or cylindrical acoustic waves. The insonifying acoustic waves are scattered by the tissue so that scattered acoustic radiation including a mix of reflected and transmitted acoustic waves is received. A representation of a portion of the tissue is then derived from the received scattered acoustic radiation.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: October 23, 2007
    Assignee: Barbara Ann Karmanos Cancer Institute
    Inventors: Nebojsa Duric, Peter J. Littrup, Earle Holsapple, III, Robert Henry Barter, Thomas L Moore, Stephen G. Azevedo, Sidney W. Ferguson
  • Diagnostic analysis of ultrasound data
    Patent number: 6984210
    Abstract: A method and apparatus are provided for investigating tissue in which acoustic data are derived from scattering a plurality of pulsed spherical or cylindrical acoustic waves from a plurality of transmission elements through the tissue to a plurality of receiving elements. The acoustic data, which include a mix of reflected and transmitted acoustic waves, are received and digitized, and a representation of a portion of the tissue is generated from the digitized acoustic data.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: January 10, 2006
    Assignee: Barbara Ann Karmanos Cancer Institute
    Inventors: David H. Chambers, Jeffrey Mast, Stephen G. Azevedo, Frank Wuebbeling, Frank Natterer, Neb Duric, Peter J. Littrup, Earle Holsapple
  • Diagnostic analysis of ultrasound data
    Publication number: 20040122325
    Abstract: A method and apparatus are provided for investigating tissue in which acoustic data are derived from scattering a plurality of pulsed spherical or cylindrical acoustic waves from a plurality of transmission elements through the tissue to a plurality of receiving elements. The acoustic data, which include a mix of reflected and transmitted acoustic waves, are received and digitized, and a representation of a portion of the tissue is generated from the digitized acoustic data.
    Type: Application
    Filed: December 18, 2002
    Publication date: June 24, 2004
    Applicant: Barbara Ann Karmanos Cancer Institute
    Inventors: David H. Chambers, Jeffrey Mast, Stephen G. Azevedo, Frank Wuebbeling, Frank Natterer, Nebojsa Duric, Peter J. Littrup, Earle Holsapple
  • Computerized ultrasound risk evaluation system
    Publication number: 20040122304
    Abstract: A method and system for examining tissue are provided in which the tissue is maintained in a position so that it may be insonified with a plurality of pulsed spherical or cylindrical acoustic waves. The insonifying acoustic waves are scattered by the tissue so that scattered acoustic radiation including a mix of reflected and transmitted acoustic waves is received. A representation of a portion of the tissue is then derived from the received scattered acoustic radiation.
    Type: Application
    Filed: December 18, 2002
    Publication date: June 24, 2004
    Applicant: Barbara Ann Karmanos Cancer Institute
    Inventors: Nebojsa Duric, Peter J. Littrup, Earle Holsapple, Robert Henry Barter, Thomas L. Moore, Stephen G. Azevedo, Sidney W. Ferguson
  • Method and apparatus for combined diagnostic and therapeutic ultrasound system incorporating noninvasive thermometry, ablation control and automation
    Publication number: 20040030227
    Abstract: A method for treating a medical pathology includes receiving a first set of acoustic radiation scattered by a volume of tissue containing at least a portion of the medical pathology and thereafter, changing a temperature of the volume of tissue. The method also includes thereafter, receiving a second set of acoustic radiation scattered by the volume of tissue and localizing the portion of the medical pathology from the first and second sets of received acoustic radiation. Localizing the portion of the medical pathology comprises identifying the medical pathology from differences in the first and second sets of received acoustic radiation resulting from the change in temperature. The method also includes insonifying the portion of the medical pathology with sufficient energy to damage the portion of the medical pathology.
    Type: Application
    Filed: May 16, 2003
    Publication date: February 12, 2004
    Applicant: Barbara Ann Karmanos Cancer Institute
    Inventors: Peter J. Littrup, Nebojsa Duric, Earle Holsapple