Abstract: An aspirator syringe is provided with an operator mechanism which allows two fingers and the thumb of one hand to be used in a fist-closing direction to operate a syringe with good, steady, continuous-motion control, while permitting the other hand to be kept free to assure that the needle is kept intact in the patient. A simple mechanism for installing and removing a conventional syringe provides stability of the syringe and mechanism during aspiration and permits aspirated fluid to be dispensed either with or without removal of the syringe from the mechanism.