Patents by Inventor Eberhard Durr

Eberhard Durr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABILIZED RSV F PROTEINS AND USES THEREOF
    Publication number: 20230141153
    Abstract: The disclosure relates to stable RSV F proteins and immunogenic compositions containing the same, as well as methods of using the immunogenic compositions and compositions comprising the RSV F proteins.
    Type: Application
    Filed: December 20, 2022
    Publication date: May 11, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Lan Zhang, Arthur Fridman, Eberhard Durr, Andrew Bett
  • Stabilized RSV F proteins and uses thereof
    Patent number: 11566051
    Abstract: The disclosure relates to stable RSV F proteins and immunogenic compositions containing the same, as well as methods of using the immunogenic compositions and compositions comprising the RSV F proteins.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: January 31, 2023
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Lan Zhang, Arthur Fridman, Eberhard Durr, Andrew Bett
  • METHOD FOR IDENTIFYING HIGH AFFINITY MONOCLONAL ANTIBODY HEAVY AND LIGHT CHAIN PAIRS FROM HIGH THROUGHPUT SCREENS OF B-CELL AND HYBRIDOMA LIBRARIES
    Publication number: 20220034902
    Abstract: A method is described for identifying high affinity monoclonal antibody heavy and light chain pairs from high throughput screens of antibody producing cell libraries such as B-cell and hybridoma libraries. Specifically, the method relates to application of reversed immunocapture and high resolution tandem mass spectrometry for the identification of heavy and light chain pairs of binding antibodies obtained from high throughput screens of antibody producing cell libraries.
    Type: Application
    Filed: December 6, 2019
    Publication date: February 3, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Eberhard Durr, Yaping Liu, Zhifeng Chen, Arthur Fridman
  • STABILIZED RSV F PROTEINS AND USES THEREOF
    Publication number: 20210300971
    Abstract: The disclosure relates to stable RSV F proteins and immunogenic compositions containing the same, as well as methods of using the immunogenic compositions and compositions comprising the RSV F proteins.
    Type: Application
    Filed: January 24, 2019
    Publication date: September 30, 2021
    Inventors: Lan Zhang, Arthur Fridman, Eberhard Durr, Andrew Bett
  • Antigen-Binding Proteins Targeting S. Aureus Orf0657n
    Publication number: 20110091480
    Abstract: The present invention features antigen binding protein that bind an ORF0657n target region (SEQ ID NO: 1). ORF0657n is an S. aureus protein. ORF0657n target regions are provided by the mAb 1G3.BD4, mAb 2H2.BE11, mAb 13C7.BC1, and mAb 13G11.BF3 binding sites. In a lethal model challenge, mAb 2H2.BE11 and mAb 13C7.BC1 provided for increased survival against S. aureus infection. There was also protection demonstrated in an ex vivo model with either the IgG1 or the IgG2b form of mAb 2H2; and in a passive immunization murine indwelling catheter model using mAb 2H2.BE11.
    Type: Application
    Filed: January 23, 2007
    Publication date: April 21, 2011
    Inventors: Martha J. Brown, Annaliesa S. Anderson, Leslie D. Cope, Kathrin Ute Jansen, Tessie McNeely, Barrett R. Harvey, Eberhard Durr, Robin Ernst
  • ANTIGEN-BINDING PROTEINS TARGETING S. AUREUS ORF0657n
    Publication number: 20100166772
    Abstract: The present invention features antigen binding proteins that bind to a region found to have an epitope that can be targeted to provide protection against S. aureus infection. The region is designated herein as the “CS-D7” target region. The CS-D7 target region provides an S. aureus ORF0657n epitope that can be targeted to reduce the likelihood or severity of an S. aureus infection.
    Type: Application
    Filed: May 29, 2008
    Publication date: July 1, 2010
    Inventors: Annaliesa S. Anderson, Desmond J. Clark, Zhiqiang An, Fubao Wang, Susan L. Secore, Eberhard Durr, Leslie D. Cope, Tessie McNeely