Abstract: The present invention is directed towards a system and method for transarterial chemoembolization using differently sized drug-eluting microsphere beads filled with drugs and determining a delivered drug concentration using an imaging system.

Abstract: Minimally-invasive spinal inventions are often performed using fluoroscopic imaging methods, which can give a real-time impression of the location of a surgical instrument, at the expense of a small field of view. When operating on a spinal column, a small field of view can be a problem, because a medical professional is left with no reference vertebra in the fluoroscopy image, from which to identify a vertebra, which is the subject of the intervention. Identifying contiguous vertebrae is difficult because such contiguous vertebrae are similar in shape. However, characteristic features, which differentiate one vertebra from other vertebra, and which are visible in the fluoroscopic view, may be used to provide a reference.

Abstract: The invention relates to an imaging system (10) for imaging an elongated region of interest of an object, an imaging method for imaging an elongated region of interest of an object, a computer program element for controlling such system for performing such method and a computer readable medium having stored such computer program element. The imaging system (10) comprises an acquisition unit (11) and a processing unit (13). The acquisition unit (11) is a C-arm acquisition unit and configured to acquire first image data of the object to be imaged with a first imaging parameter. The acquisition unit (11) is further configured to acquire second, different image data of an object to be imaged with a second imaging parameter. The second geometric imaging parameter is defined based on object specific data for the volume data to be aligned with the elongated region of interest of the object to be imaged. The processing unit (13) is configured to combine the first and second image data into volume data.

Abstract: The present invention relates to an imaging system (10) for a vertebral level, an identification method for a vertebral level, a computer program element for controlling such system and a computer readable medium having stored such computer program element. The imaging system (10) comprises a determination unit (11), a definition unit (12), an imaging unit (13), and a processing unit (14). The determination unit (11) determines a target vertebral level. The definition unit (12) defines an anatomical landmark of a spine. The imaging unit (13) provides a series of X-ray images along the spine based on the landmark. The processing unit (14) identifies the target vertebral level in at least one of the X-ray images. The processing unit (14) further stitches the X-ray images to a continuous panoramic image of the spine and identifies the target vertebral level in the panoramic image.

Abstract: The invention relates to an imaging device (10) for registration of different imaging modalities, an imaging system (1) for registration of different imaging modalities, a method for registration of different imaging modalities, a computer program element for controlling such device and a computer readable medium having stored such computer program element. The imaging system (1) for registration of different imaging modalities comprises a first imaging modality (2), a second imaging modality (3), and an imaging device (10) for registration of different imaging modalities. The imaging device (10) for registration of different imaging modalities comprises a model provision unit (11), a first image data provision unit (12), a processing unit (13), a second image data provision unit (14), and a registration unit (15). The model provision unit (11) provides a cavity model of a visceral cavity. The first showing a region of interest of a patient by the first imaging modality (2).

Abstract: The present invention relates to a method for segmenting MR Dixon image data. A processor and a computer program product are also disclosed for use in connection with the method. The invention finds application in the MR imaging field in general and more specifically may be used in the generation of an attenuation map to correct for attenuation by cortical bone during the reconstruction of PET images. In the method, a surface mesh is adapted to a region of interest by: for each mesh element in the surface mesh: selecting a water target position based on a water image feature response in the MR Dixon water image; selecting a fat target position based on a fat image feature response in the MR Dixon fat image; and displacing each mesh element from its current position to a new position based on both its water target position and its corresponding fat target position.

Abstract: A medical imaging system includes a data store (16) of reconstruction procedures, a selector (24), a reconstructor (14), a fuser (28), and a display (22). The data store (16) of reconstruction procedures identifies a plurality of reconstruction procedures. The selector (24) selects at least two reconstruction procedures from the data store of reconstruction procedures based on a received input, each reconstruction procedure optimized for one or more image characteristics. The reconstructor (14) concurrently performs the selected at least two reconstruction procedures, each reconstruction procedure generates at least one image (26) from the at least one data store of imaging data (12). The fuser (28) fuses the at least two generated medical images to create a medical diagnostic image which includes characteristics from each generated image (26). The display (22) displays the medical diagnostic image.

Abstract: A reconstruction apparatus (9) reconstructs a PET image. A first detector (3) generates first detection events and detection times assigned to the first detection events and a second detector (6) generates second detection events and detection times assigned to the second detection events. A timing window determination unit (11) provides a first-second timing window by providing a first-second upper threshold based on the position of the second detector relative to the first detector and a detection event pairs generation unit (12) generates first-second detection event pairs based on the provided first-second timing window. The first-second detection event pairs are used for reconstructing the PET image. The first-second timing window depends on the position of the second detector leads to an improved generation of first-second detection event pairs, which in turn can lead to an improved PET image.

Abstract: A magnetic resonance method of electric properties tomography imaging of an object includes applying an excitation RF field to the object via a coil at a first spatial coil position (402), acquiring resulting magnetic resonance signals via a receiving channel from the object, determining from the acquired magnetic resonance signals a first phase distribution and a first amplitude of a given magnetic field component of the excitation RF field of the coil at the first coil position (402), repeating these steps with a coil at a second different spatial coil position (404), to obtain a second phase distribution, determining a phase difference between the first and second phase distribution, determining a first and a second complex permittivity of the object, the first complex permittivity comprising the first amplitude of the given magnetic field component and the second complex permittivity comprising the second amplitude of the given magnetic field component and the phase difference, equating the first complex

Abstract: An x-ray computed tomography system (14) includes a gantry (15), a plurality of elements (18), and one or more processors (28). The gantry (15) moves to different orientations and generates x-ray data which includes image projection data at a plurality of the orientations. The plurality of elements (18) connect to the gantry and cause x-ray attenuation of the generated projection data. The one or more processors (28) are programmed to receive (60) the generated x-ray data and decompose (62) the received image projection data into indications of relative positions of the plurality of elements at different orientations of the gantry.

Abstract: The present invention relates to a guidance device (10) for a TEE probe (20), a medical imaging system (1), a method for guiding a TEE probe (20), a computer program element for controlling such device and a computer readable medium having stored such computer program element. The guidance device (10) for a TEE probe (20) comprises an image data provision unit (11), and a processing unit (12). The image data provision unit (11) is configured to provide first image data showing an interventional device (40) and a TEE probe (20) in an initial position and orientation. The processing unit (12) is configured to determine a center-line of the interventional device (40)in the first image data. The processing unit (12) is configured to determine a plane (41) orthogonal to a tangent of the centerline as viewing plane. The processing unit (12) is configured to calculate an imaging plane and an imaging orientation of the TEE probe (20) to lie approximately in the viewing plane.

Abstract: The invention relates to a reconstruction apparatus (9) for reconstructing a PET image. A first detector (3) generates first detection events and detection times assigned to the first detection events and a second detector (6) generates second detection events and detection times assigned to the second detection events. A timing window determination unit (11) provides a first-second timing window by providing a first-second upper threshold based on the position of the second detector relative to the first detector and a detection event pairs generation unit (12) generates first-second detection event pairs based on the provided first-second timing window, wherein the first-second detection event pairs are used for reconstructing the PET image. The provision of the first-second timing window depending on the position of the second detector can lead to an improved generation of first-second detection event pairs, which in turn can lead to an improved PET image.

Abstract: A multiple modality imaging system includes a cone-beam computed tomography scanner which acquires CT projection data of a subject in an examination region and a nuclear imaging scanner which concurrently/subsequently acquires nuclear projection data of the subject in the examination region. A CT reconstruction processor is programmed to perform the steps of: in the CT projection data, defining a field-of-view (FoV) with a voxel grid in a trans-axial direction; determining the subject's maximum trans-axial extents; generating an extending FoV by extending the voxel grid of the FoV to at least one extended region outside the FoV that encompass at least the determined maximum trans-axial extents and all attenuation in the trans-axial direction; and iteratively reconstructing the CT projection data into an attenuation map of the extended FoV. At least one nuclear reconstruction processor is programmed to correct the acquired nuclear projection data based on the iteratively reconstructed attenuation map.

Abstract: A hybrid imaging system including a first imaging system configured to acquire low resolution anatomical data of a first field of view of an anatomical structure. A second imaging system is configured to acquire functional data of the first field of view of the anatomical structure. A reconstruction processor is configured to reconstruct the functional data based on attenuation data into an attenuation corrected image. In response to the attenuation corrected image showing regions of interest, with the first imaging system or another imaging system acquiring high resolution data of one or more portions of the first field of view containing the regions of interest. The reconstruction processor reconstructs the high resolution anatomical data into one or more high resolution images of the regions of interest.

Abstract: The invention relates to a navigation system for navigating an interventional device (11) like a catheter and an interventional system comprising the navigation system. A position and shape determining unit (13) determines and stores a first position and shape of the interventional device within a living being (9) during a first interventional procedure like a first chemoembolization session and determines a second position and shape of an interventional device within the living being during a subsequent second interventional procedure like a second chemoembolization session. During the second interventional procedure the interventional device is navigated based on the stored first position and shape and based on the second position and shape. This allows considering during the second interventional procedure the path of the interventional device used during the first interventional procedure.

Abstract: In Positron Emission Tomography, a time window (260) and an energy window (225) are dynamically adjusted, based on an attenuation map, count rate, clinical application, discrimination tailoring, and/or offline discrimination tailoring. Detected radiation events are filtered using the dynamically adjusted energy and time windows into scattered events, random events, and true events. The true events are input to image reconstruction, correction, and error analysis.

Abstract: The present invention relates to a method for segmenting MR Dixon image data. A processor and a computer program product are also disclosed for use in connection with the method. The invention finds application in the MR imaging field in general and more specifically may be used in the generation of an attenuation map to correct for attenuation by cortical bone during the reconstruction of PET images. In the method, a surface mesh is adapted to a region of interest by: for each mesh element in the surface mesh: selecting a water target position based on a water image feature response in the MR Dixon water image; selecting a fat target position based on a fat image feature response in the MR Dixon fat image; and displacing each mesh element from its current position to a new position based on both its water target position and its corresponding fat target position.

Abstract: A method and system for reducing localized artifacts in imaging data, such as motion artifacts and bone streak artifacts, are provided. The method includes segmenting the imaging data to identify one or more suspect regions in the imaging data near which localized artifacts are expected to occur, defining an artifact-containing region of interest in the imaging data around each suspect region, and applying a local bias field within the artifact-containing regions to correct for the localized artifacts.

Abstract: A method comprises: acquiring imaging data using a tomographic radiological imaging apparatus (10); updating a calibration (42, 52) based on current information about the imaging apparatus; calibrating the imaging data using the up-to-date calibration; and reconstructing the calibrated imaging data to generate an image. The updating may be based on a current state of an idle or parked imaging modality that is not used in acquiring the imaging data, or on a measurement acquired together with the imaging data, or on the imaging data itself. For cone-beam computed tomography (CBCT) imaging data, the updating may comprise determining an intensity scale based upon intensity of at least one air pixel measured during the acquiring of the CBCT imaging data and updating an air scan template (60) by the intensity scale.

Abstract: A method includes performing a motion compensated reconstruction of functional projection data using a patient-adapted motion model, which is generated based on a generic anatomical motion model and imaging data from a structural scan. A system includes a first adapter (202) configured to adapt a generic anatomical model to structural image data, producing an adapted model, a forward projector (204) configured to forward project the adapted model, producing forward projected data, and a second adapter (206) configured to adapt the forward projected data to individual projections of projected data, which is used to generate the structural image data, producing a patient-adapted motion model.