Patents by Inventor Eberhard Straube

Eberhard Straube has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for enriching and/or separating prokaryotic DNA using a protein that specifically bonds to unmethylated DNA containing CpG-motifs
    Patent number: 8481262
    Abstract: The invention relates to a method for separating and/or enriching prokaryotic DNA, comprising the following steps: a) contacting of at least one prokaryotic DNA that is in solution with a protein that bonds specifically to prokaryotic DNA, the protein being 25%-35% homologous with the wild-type CGPB protein, thus forming a protein-DNA complex; and b) separation of the complex. The invention also relates to a kit for carrying out said method.
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: July 9, 2013
    Assignee: SIRS-Lab GmbH
    Inventors: Karl-Hermann Schmidt, Eberhard Straube, Stefan Russwurm, Hans-Peter Deigner, Svea Sachse, Marc Lehmann
  • Method for enriching a prokaryotic DNA
    Patent number: 8288115
    Abstract: A method is described for enriching procaryotic DNA, said method including the steps of contacting at least one procaryotic DNA with at least one protein or polypeptide which is capable of specifically binding to non-methylated CpG motifs, and separating the protein/polypeptide-DNA complex. Moreover, the application relates to a kit for carrying out said method.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: October 16, 2012
    Assignee: SIRS-Lab GmbH
    Inventors: Karl-Hermann Schmidt, Eberhard Straube, Stefan Russwurm
  • METHOD FOR ENRICHING A PROKARYOTIC DNA
    Publication number: 20120040363
    Abstract: A method is described for enriching procaryotic DNA, said method including the steps of contacting at least one procaryotic DNA with at least one protein or polypeptide which is capable of specifically binding to non-methylated CpG motifs, and separating the protein/polypeptide-DNA complex. Moreover, the application relates to a kit for carrying out said method.
    Type: Application
    Filed: October 5, 2011
    Publication date: February 16, 2012
    Applicant: SIRS-LAB GMBH
    Inventors: Karl-Hermann SCHMIDT, Eberhard STRAUBE, Stefan RUSSWURM
  • Method for enriching a prokaryotic DNA
    Patent number: 8062854
    Abstract: A method is described for enriching procaryotic DNA, said method including the steps of contacting at least one procaryotic DNA with at least one protein or polypeptide which is capable of specifically binding to non-methylated CpG motifs, and separating the protein/polypeptide-DNA complex. Moreover, the application relates to a kit for carrying out said method.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: November 22, 2011
    Assignee: SIRS-Lab GmbH
    Inventors: Karl-Hermann Schmidt, Eberhard Straube, Stefan Russwurm
  • METHOD FOR ENRICHING A PROKARYOTIC DNA
    Publication number: 20100316993
    Abstract: A method is described for enriching procaryotic DNA, said method including the steps of contacting at least one procaryotic DNA with at least one protein or polypeptide which is capable of specifically binding to non-methylated CpG motifs, and separating the protein/polypeptide-DNA complex. Moreover, the application relates to a kit for carrying out said method.
    Type: Application
    Filed: August 8, 2003
    Publication date: December 16, 2010
    Inventors: Karl-Hermann Schmidt, Eberhard Straube, Stafan Russwurm
  • Method for Recognizing Acute Generalized Inflammatory Conditions (Sirs), Sepsis, Sepsis-Like Conditions and Systemic Infections
    Publication number: 20080070235
    Abstract: The present invention relates to a method for in vitro detection of SIRS, sepsis and/or sepsis-like conditions. This method renders the evaluation of the severity and/or the therapeutic progress of sepsis and severe infections, in particular sepsis-like systemic infections possible. Further, the present invention relates to the use of recombinantly or synthetically prepared nucleic acid sequences or peptide sequences derived therefrom as calibrator in sepsis assays and/or for the evaluation of the effect and the toxicity during screening of the active agents and/or the preparation of therapeutics for the prevention and treatment of SIRS, sepsis, sepsis-like systemic inflammatory conditions and sepsis-like systemic infections.
    Type: Application
    Filed: March 31, 2004
    Publication date: March 20, 2008
    Applicant: SIRS-Lab GMBH
    Inventors: Stefan Russwurm, Konrad Reinhart, Hans-Peter Saluz, Eberhard Straube, Peter Zipfel, Hans-Peter Deigner
  • Method for Enriching and/or Separating Prokaryotic Dna Using a Protein that Specifically Bonds to Unmethylated Dna Containing Cpg-Motives
    Publication number: 20080003568
    Abstract: The invention relates to a method for separating and/or enriching prokaryotic DNA, comprising the following steps: a) contacting of at least one prokaryotic DNA that is in solution with a protein that bonds specifically to prokaryotic DNA, said protein being 25%-35% homologous with the wild-type CGPB protein, thus forming a protein-DNA complex; and b) separation of the complex. The invention also relates to a kit for carrying out said method.
    Type: Application
    Filed: March 2, 2005
    Publication date: January 3, 2008
    Inventors: Karl-Hermann Schmidt, Eberhard Straube, Stefan Russwurm, Hans-Peter Deigner, Svea Sachse, Marc Lehmann