Patents by Inventor Eckart H. Bindewald

Eckart H. Bindewald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Auto-recognizing therapeutic RNA/DNA chimeric nanoparticles (NP)
    Patent number: 9631192
    Abstract: Auto-recognizing therapeutic R/DNA chimeric nanoparticles (R/DNA NP) are described that are pairs of DNA/RNA hybrids where the DNA molecules have complementary toehold sequences that promote the re-association of the R/DNA NPs when mixed resulting in the formation of RNA/RNA duplexes that act as siRNAs.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: April 25, 2017
    Assignees: The United States of America, as represented by the Secretary, Department of Health & Human Services, The Regents of the University of California
    Inventors: Bruce A. Shapiro, Kirill A. Afonin, Mathias D. Viard, Eckart H. Bindewald, Luc Jaeger, Arti N. Santhanam
  • THERAPEUTIC RNA SWITCHES COMPOSITIONS AND METHODS OF USE
    Publication number: 20150240238
    Abstract: The invention provides for therapeutic RNA switches comprising oligonucleotide sequences complementary to a trigger sequence, an antisense strand oligonucleotide, and a sense strand oligonucleotide complementary to a target nucleic acid molecule.
    Type: Application
    Filed: November 19, 2012
    Publication date: August 27, 2015
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Bruce A. Shapiro, Eckart H. Bindewald, Kirill A. Afonin, Luc Jaeger, Arti N. Santhanam
  • AUTO-RECOGNIZING THERAPEUTIC RNA/DNA CHIMERIC NANOPARTICLES (NP)
    Publication number: 20140303237
    Abstract: Auto-recognizing therapeutic R/DNA chimeric nanoparticles (R/DNA NP) are described that are pairs of DNA/RNA hybrids where the DNA molecules have complementary toehold sequences that promote the re-association of the R/DNA NPs when mixed resulting in the formation of RNA/RNA duplexes that act as siRNAs.
    Type: Application
    Filed: November 19, 2012
    Publication date: October 9, 2014
    Inventors: Bruce A. Shapiro, Kirill A. Afonin, Mathias D. Viard, Eckart H. Bindewald