Patents by Inventor Eckhard Bender

Eckhard Bender has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted piperidines
    Publication number: 20120149694
    Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and tumour disorders.
    Type: Application
    Filed: May 14, 2010
    Publication date: June 14, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Ulrich Rester, Eckhard Bender, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gerdes, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
  • Substituted piperidines
    Publication number: 20120142690
    Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and tumour disorders.
    Type: Application
    Filed: May 18, 2010
    Publication date: June 7, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Ulrich Rester, Eckhard Bender, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gnoth, Kersten Matthias Gericke, Mario Jeske
  • Substituted piperidines
    Publication number: 20120135985
    Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular diseases and tumour diseases.
    Type: Application
    Filed: May 18, 2010
    Publication date: May 31, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Eckhard Bender, Katja Zimmermann, Anja Buchmüller, Christoph Gerdes, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
  • Substituted 3-(1,2,4-Oxadiazol-5-yl)-5-Phenylpiperidines
    Publication number: 20120129831
    Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and tumour disorders.
    Type: Application
    Filed: May 14, 2010
    Publication date: May 24, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Dirk Schneider, Ulrich Rester, Eckhard Bender, Mark Meininghaus, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gerdes, Michael Gerisch, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
  • Substituted piperidines as Par-1 Antagonists
    Publication number: 20120046268
    Abstract: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumour disorders.
    Type: Application
    Filed: March 12, 2010
    Publication date: February 23, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Mario Jeske, Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Dirk Schneider, Ulrich Rester, Eckhard Bender, Mark Meininghaus, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gerdes, Michael Gerisch, Mark Jean Gnoth, Kersten Matthias Gericke
  • Heteroaryl-substituted piperidines
    Patent number: 8119663
    Abstract: The invention relates to novel heteroaryl-substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular diseases and tumor diseases.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: February 21, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Dirk Heimbach, Susanne Röhrig, Dirk Schneider, Ulrich Rester, Eckhard Bender, Mark Meininghaus, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gerdes, Michael Gerisch, Mark Jean Gnoth, Yolanda Cancho Grande, Mario Jeske, Kersten Matthias Gericke
  • Substituted arylimidazolone and triazolone as inhibitors of vasopressin receptors
    Patent number: 8084481
    Abstract: The present application relates to novel, substituted 4-arylimidazol-2-ones and 5-aryl-1,2,4-triazolones, processes for the production thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases and the use thereof for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: December 27, 2011
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Heinrich Meier, Eckhard Bender, Ulf Brüggemeier, Ingo Flamme, Dagmar Karthaus, Peter Kolkhof, Daniel Meibom, Dirk Schneider, Verena Voehringer, Chantal Fürstner, Jörg Keldenich, Dieter Lang, Elisabeth Pook, Carsten Schmeck
  • Substituted piperidines
    Patent number: 8084469
    Abstract: The invention relates to compounds of the formula (I) to processes for the preparation thereof, and to the use thereof for the treatment of cardiovascular disorders and tumor disorders.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: December 27, 2011
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Eckhard Bender, Katja Zimmermann, Anja Buchmüller, Christoph Gerdes, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
  • SUBSTITUTED PIPERIDINES
    Publication number: 20110021489
    Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and tumour disorders.
    Type: Application
    Filed: May 27, 2010
    Publication date: January 27, 2011
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Dirk HEIMBACH, Susanne Röhrig, Yolanda Cancho Grande, Eckhard Bender, Katja Zimmermann, Anja Buchmüller, Christoph Gerdes, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
  • SUBSTITUTED PIPERIDINES
    Publication number: 20100305111
    Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular diseases and tumour diseases.
    Type: Application
    Filed: May 27, 2010
    Publication date: December 2, 2010
    Applicant: BAYER SCHERING PHARMA
    Inventors: Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Eckhard Bender, Katja Zimmermann, Anja Buchmüller, Christoph Gerdes, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
  • Substituted Arylimidazolone and Triazolone as Inhibitors of Vasopressin Receptors
    Publication number: 20090312381
    Abstract: The present application relates to novel, substituted 4-arylimidazol-2-ones and 5-aryl-1,2,4-triazolones, processes for the production thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases and the use thereof for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
    Type: Application
    Filed: May 21, 2007
    Publication date: December 17, 2009
    Applicant: BAYER HEALTHCARE AG
    Inventors: Heinrich Meier, Eckhard Bender, Ulf Brüggemeier, Ingo Flamme, Dagmar Karthaus, Peter Kolkhof, Daniel Meibom, Dirk Schneider, Verena Voehringer, Chantal Fürstner, Jörg Keldenich, Dieter Lang, Elisabeth Pook, Carsten Schmeck
  • HETEROARYL-SUBSTITUTED PIPERIDINES
    Publication number: 20090306139
    Abstract: The invention relates to novel heteroaryl-substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular diseases and tumour diseases.
    Type: Application
    Filed: November 25, 2008
    Publication date: December 10, 2009
    Applicant: BAYER HEALTHCARE AG
    Inventors: Dirk Heimbach, Susanne Rohrig, Dirk Schneider, Ulrich Rester, Eckhard Bender, Mark Meininghaus, Katja Zimmermann, Dmitry Zubov, Anja Buchmuller, Georges Von Degenfeld, Christoph Gerdes, Michael Gerisch, Mark Jean Gnoth, Yolanda Cancho Grande, Mario Jeske, Kersten Matthias Gericke
  • EPF derived peptides and therapeutic compositions
    Patent number: 7402563
    Abstract: The present invention provides assays for the study of the interaction of EPF and its EPF-related peptides with a hDRR receptor. The assays are useful to identify whether a test compound can bind to the hDRR receptor under conditions in which EPF or related peptide can bind to the receptor. The assays are also useful to determine whether the test compound is an agonist or antagonist of hDRRs. The above assays can be performed in a variety of formats including competitive, non-competitive and comparative assays in which the interaction of EPF or EPF-related peptides with hDRRs is assessed as a positive or negative control or compared to the results obtained with the test compound.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: July 22, 2008
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Arjan Buist, Eckhard Bender, Tom J. L. Meeusen, Elke J. H. Clynen, Liliane A. H. Schoofs
  • G protein coupled receptor
    Publication number: 20070087388
    Abstract: The invention provides nucleic acid encoding a G protein coupled receptor (adenine binding GPCR) with specificity for adenine, isolated adenine binding GPCR, assay and treatment methods utilising the same.
    Type: Application
    Filed: July 28, 2006
    Publication date: April 19, 2007
    Inventors: Eckhard Bender, Arjan Buist, Martine Ercken, Walter Herman Luyten, Mirek Jurzak, Liliane Schoofs, Geert Luc Baggerman
  • EPF receptor assays, compounds and therapeutic compositions
    Publication number: 20060160145
    Abstract: The present invention provides assays for the study of the interaction of EPF and its EPF-related peptides with a hDRR receptor. The assays are useful to identify whether a test compound can bind to the hDRR receptor under conditions in which EPF or related peptide can bind to the receptor. The assays are also useful to determine whether the test compound is an agonist or antagonist of hDRRs. The above assays can be performed in a variety of formats including competitive, non-competitive and comparative assays in which the interaction of EPF or EPF-related peptides with hDRRs is assessed as a positive or negative control or compared to the results obtained with the test compound.
    Type: Application
    Filed: March 22, 2006
    Publication date: July 20, 2006
    Applicant: Janssen Pharmaceutica N.V.
    Inventors: Arjan Buist, Eckhard Bender, Tom Meeusen, Elke Clynen, Liliane Schoofs
  • Cloning and expression of a novel 5-HT4 receptor
    Patent number: 6998244
    Abstract: There is disclosed an isolated or substantially pure form of a nucleic acid molecule encoding a human 5-HT4(h) receptor, which 5-HT4(h) receptor preferably comprises the sequence illustrated in FIG. 1B. Also provided by the invention are expression vectors incorporating said nucleic acid molecule in addition to transgenic cells, tissues or organisms transfected with the nucleic acid molecule.
    Type: Grant
    Filed: June 14, 2000
    Date of Patent: February 14, 2006
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Eckhard Bender, Armelle Nathalie Françoise Pindon, Irma Petronella Van Oers, Mirek Jurzak, Walter Herman Maria Louis Luyten
  • Epf receptor assays, compounds and therapeutic compositions
    Publication number: 20040235722
    Abstract: The present invention provides assays for the study of the interaction of EPF and its EPF-related peptides with a hDRR receptor. The assays are useful to identify whether a test compound can bind to the hDRR receptor under conditions in which EPF or related peptide can bind to the receptor. The assays are also useful to determine whether the test compound is an agonist or antagonist of hDRRs. The above assays can be performed in a variety of formats including competitive, non-competitive and comparative assays in which the interaction of EPF or EPF-related peptides with hDRRs is assessed as a positive or negative control or compared to the results obtained with the test compound.
    Type: Application
    Filed: December 17, 2003
    Publication date: November 25, 2004
    Inventors: Arjan Buist, Eckhard Bender, Tom, Julia, Leon Meeusen
  • G protein coupled receptor
    Publication number: 20030157516
    Abstract: The invention provides nucleic acid encoding a G protein coupled receptor (adenine binding GPCR) with specificity for adenine, isolated adenine binding GPCR, assay and treatment methods utilising the same.
    Type: Application
    Filed: October 4, 2002
    Publication date: August 21, 2003
    Inventors: Eckhard Bender, Arjan Buist, Martine Ercken, Walter Herman Maria Louis Luyten, Mirek Jurzak