Patents by Inventor Eckhard Claus

Eckhard Claus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridopyrazines and the use thereof as kinase inhibitors
    Patent number: 7323468
    Abstract: The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general Formula I, their preparation and use as medicaments, in particular for the treatment of malignant and other disorders based on pathological cell proliferations.
    Type: Grant
    Filed: May 21, 2004
    Date of Patent: January 29, 2008
    Assignee: AEterna Zentaris GmbH
    Inventors: Eckhard Claus, Eckhard Günther, Irene Seipelt, Ulf R. Rapp, Ludmilla Wixler
  • Pyridopyrazines and the use thereof as kinase inhibitors
    Publication number: 20070275972
    Abstract: The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general Formula I, their preparation and use as medicaments, in particular for the treatment of malignant and other disorders based on pathological cell proliferations.
    Type: Application
    Filed: July 5, 2007
    Publication date: November 29, 2007
    Inventors: Eckhard Claus, Eckhard Gunther, Irene Speipelt, Ulf Rapp, Ludmilla Wixler
  • Pyridopyrazines and the use thereof as kinase inhibitors
    Patent number: 7276507
    Abstract: The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general Formula I, their preparation and use as medicaments, in particular for the treatment of malignant and other disorders based on pathological cell proliferations
    Type: Grant
    Filed: May 21, 2004
    Date of Patent: October 2, 2007
    Assignee: AEterna Zentaris GmbH
    Inventors: Eckhard Claus, Eckhard Günther, Irene Seipelt, Ulf R. Rapp, Ludmilla Wixler
  • NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES
    Publication number: 20070149484
    Abstract: The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general formulae (I) and (II), and to their preparation and use as medicaments, especially for the treatment of malignant disorders and other disorders based on pathological cell proliferations.
    Type: Application
    Filed: November 10, 2006
    Publication date: June 28, 2007
    Applicant: ZENTARIS GmbH
    Inventors: Eckhard Claus, Irene Seipelt, Eckhard Guenther, Emmanuel Polymeropoulos, Michael Czech, Tilmann Schuster
  • PYRIDOPYRAZINE DERIVATIVES AND THEIR USE
    Publication number: 20070123494
    Abstract: The present invention provides new pyridopyrazine compounds which are suitable for the treatment or prevention of physiological and/or pathophysiological states mediated and/or modulated by signal transduction pathways and/or enzymes in mammals and in particular in humans.
    Type: Application
    Filed: November 10, 2006
    Publication date: May 31, 2007
    Applicant: ZENTARIS GmbH
    Inventors: Irene SEIPELT, Eckhard Claus, Eckhard Guenther, Tilmann Schuster, Michael Czech, Emmanuel Polymeropoulos
  • Pyridopyrazines and the use thereof as kinase inhibitors
    Publication number: 20050032803
    Abstract: The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general Formula I, their preparation and use as medicaments, in particular for the treatment of malignant and other disorders based on pathological cell proliferations.
    Type: Application
    Filed: May 21, 2004
    Publication date: February 10, 2005
    Inventors: Eckhard Claus, Eckhard Gunther, Irene Seipelt, Ulf Rapp, Ludmilla Wixler
  • Pyridopyrazines and the use thereof as kinase inhibitors
    Publication number: 20040266777
    Abstract: The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general Formula I, their preparation and use as medicaments, in particular for the treatment of malignant and other disorders based on pathological cell proliferations.
    Type: Application
    Filed: May 21, 2004
    Publication date: December 30, 2004
    Inventors: Eckhard Claus, Eckhard Gunther, Irene Seipelt, Ulf R. Rapp, Ludmilla Wixler
  • Ratjadone derivatives for inhibiting cell growth
    Publication number: 20040092581
    Abstract: The invention relates to ratjadone derivatives which can stop the cell cycle of tumour cells in the G1 phase and/or exhibit a reduced cytotoxicity as ratjadone. According to the invention, the ratjadone derivatives correspond to formula (II) wherein R1, R2 and R3 are selected independently from each other from the group which is made of H, CH3 and C2H5, R4 is CH3 or C2H5, R5 is H or OH and R6 and R7 are selected independently from each other from the group which is made of H, CH3, C2H5, n-C3H7, and iso C3H7, and wherein C10 is R-configured and C17 is R-configured if (a) C16 is R-configured and simultaneously (b) neither R5, nor R6, nor R7 are H. The invention also relates to a method for synthesizing ratjadone derivatives.
    Type: Application
    Filed: August 12, 2003
    Publication date: May 13, 2004
    Inventors: Arne Burzlaff, Cornelia Kasper, Thomas Scheper, Markus Kalesse, Ulhas Bhatt, Khandavalli Chary, Eckhard Claus, Mathias Christmann, Monika Quitschalle, Winfried Beil