Patents by Inventor Eckhard Nikolaiski

Eckhard Nikolaiski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-Oxy-substituted derivatives of Psoralene useful in dermatology
    Patent number: 4217445
    Abstract: An improved process for obtaining 5-methoxy-psoralene from bergamot oil, a method for preparing the compound 5-hydroxy-psoralene from 5-methoxy-psoralene and a method of making novel psoralene derivatives by replacing the hydrogen atom of the 5-hydroxy group with an R group are disclosed. These compounds are prepared by reacting the 5-hydroxy-psoralene with a halide RX in the presence of sodium hydride. Compounds of particular interest are those of which the radical R is: alkanoyl of not more than 10 carbon atoms; orthoacetoxy-benzoyl; .alpha.thenoyl; O,O diethyl-phosphono; diethylaminoethyl, and 2'3'4'6' tetra .alpha. acetyl D-gluco pyranosyl.
    Type: Grant
    Filed: May 26, 1977
    Date of Patent: August 12, 1980
    Assignee: Fotobio Holding AG
    Inventor: Eckhard Nikolaiski