Abstract: A method for depositing samples, in which at least one sample (10) is arranged on a substrate (30), comprises the following steps: positioning a sample dispenser (20) above the substrate (30), and actuating the sample dispenser (20) so that the sample (10) is moved from the sample dispenser (20) along a trajectory (11) to a predefined deposition position (32) on the substrate (30), wherein at least part of the trajectory (11) is shielded against electrical interference fields. Also described is a substrate (30) for receiving samples (10), comprising a substrate body (31), on the surface of which at least one deposition position (32) is provided, and a shielding electrode (40), which is designed so as to electrostatically shield the space above the at least one deposition position (32) against electrical interference fields.

Abstract: A method for depositing samples, in which at least one sample (10) is arranged on a substrate (30), comprises the following steps: positioning a sample dispenser (20) above the substrate (30), and actuating the sample dispenser (20) so that the sample (10) is moved from the sample dispenser (20) along a trajectory (11) to a predefined deposition position (32) on the substrate (30), wherein at least part of the trajectory (11) is shielded against electrical interference fields. Also described is a substrate (30) for receiving samples (10), comprising a substrate body (31), on the surface of which at least one deposition position (32) is provided, and a shielding electrode (40), which is designed so as to electrostatically shield the space above the at least one deposition position (32) against electrical interference fields.

Abstract: The present invention relates to a method for identifying and/or characterizing a (poly)peptide comprising: (a) analyzing a peptide map of said (poly)peptide, comprising at least 1 peptide, and its peptide primary structure fingerprint by mass spectrometry; and (b) comparing data obtained in step (a) with a reference (poly)peptide database, said database comprising mass spectrometric data of peptide maps, comprising at least 1 peptide, and of its peptide primary structure fingerprint, of a (poly)peptide or of a variety of (poly)peptides.

Abstract: The invention relates to the use of surfaces having hydrophilic and/or oleophilic areas, each of which being completely surrounded by the ultraphobic areas, for analyzing samples. The invention also relates to a method for precisely dosing liquids without contaminating them.

Abstract: The invention relates to a planar structure, particularly a plate, having an ultraphobic surface on which the hydrophilic and/or oleophilic areas can be reversibly produced. The invention also relates to a planar structure comprising an ultraphobic surface provided with hydrophilic and/or oleophilic areas that are each completely surrounded by ultraphobic areas. The invention additionally relates to methods for reversibly producing hydrophilic and/or oleophilic areas on ultraphobic surfaces, to the deposition of liquid drops onto the inventive planar structure, and to the use of the inventive planar structure for conducting mass spectroscopic and/or optical analysis of aqueous liquids.

Abstract: The invention relates to the use of surfaces having hydrophilic and/or oleophilic areas, each of which being completely surrounded by the ultraphobic areas, for analyzing samples. The invention also relates to a method for precisely dosing liquids without contaminating them.

Abstract: The invention relates to a planar structure having an ultraphobic surface and at least one hydrophilic and/or oleophilic area that, in addition to being hydrophilic and/or oleophilic, has at least one additional functionality. The invention also relates to a method for producing the inventive planar structure and to the use thereof.

Abstract: The invention relates to a process for the isolation and/or purification of a proteinaceous material, wherein a solid phase comprising a mixture of hydrophobic and hydrophilic groups is used.

Abstract: The invention relates to methods and devices used for digesting small amounts of protein in tiny cut gel pieces and for extracting the peptides resulting from the digestion in preparation for analysis by mass spectrometry. The invention involves digesting proteins using enzymes within the gel pieces in vessels which have permeable but lyophobic bases in such a manner that they scarcely touch the walls of the vessel, and then rapidly removing the digested proteins from the gel pieces almost completely by gentle centrifuging. It is then advantageous to bond the peptides reversibly to suitable surfaces as quickly as possible. For this purpose, the bases of the vessels may contain structures for bonding the peptides which are suitable for washing and subsequently eluting the peptides. A number of vessels can be combined together to form plates which, for example, can have the size of microtiter plates.

Abstract: The invention relates to methods and devices used for digesting small amounts of protein in tiny cut gel pieces and for extracting the peptides resulting from the digestion in preparation for analysis by mass spectrometry.

Abstract: The invention relates to a process for the isolation and/or purification of a proteinaceous material, wherein a solid phase comprising a mixture of hydrophobic and hydrophilic groups is used.