Patents by Inventor Eckhard THINES

Eckhard THINES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220340918
    Abstract: The present invention provides to a method for the introducing polynucleotide molecules into fungal spores comprising exposing a mixture of fungal spores and magnetic nanoparticles carrying the polynucleotide to a magnet and/or a magnetic field. The present invention also provides a method for transformation a fungus comprising the steps of the method steps disclosed herein and allowing the integration of said polynucleotide molecules into the genome of said spores, thereby transforming the spore. The present invention also provides a system for delivery of nucleic acids to fungal spores comprising magnetic nanoparticles loaded with nucleic acids, a kit for transformation of fungal spores with a polynucleotide comprising MNPs loaded with the polynucleotide and fungal spores as well as a composition comprising MNPs loaded with nucleic acid molecules and fungal spores.
    Type: Application
    Filed: June 17, 2020
    Publication date: October 27, 2022
    Inventors: Maarten Hendrik Stuiver, Doreen Schachtschabel, Birgit Hoff, Tobias Mentzel, Isabella Siepe, Eckhard Thines, Stefan Jacob, Michael Becker, Alexander Yemelin
  • Patent number: 11311010
    Abstract: The present invention provides lignin nanoparticles containing a hydrophobic active agent and a process for the production of the lignin nanoparticles. The process involves the following steps: (i) dissolving modified lignin and a hydrophobic active agent in an organic solvent having low solubility in water; (ii) combining the solution with water and a surfactant to form a pre-emulsion; (iii) forming an emulsion from the pre-emulsion; and (iv) crosslinking the modified lignin to form the lignin nanoparticles, in which the modified lignin is lignin which is chemically modified to contain at least two functional groups suitable for polymerization and/or crosslinking.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: April 26, 2022
    Assignees: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V., INSTITUT FÜR BIOTECHNOLOGIE UND WIRKSTOFF-FORSCHUNG GGMBH
    Inventors: Frederik Wurm, Katharina Landfester, Doungporn Yiamsawas, Eckhard Thines, Jochen Fischer
  • Publication number: 20210355433
    Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.
    Type: Application
    Filed: July 19, 2021
    Publication date: November 18, 2021
    Inventors: Isabella Siepe, Heilke Brueser, Kristin Klappach, Karl-Heinrich Schneider, Petra Sproete, Kerstin Hage, Birgit Blanz, Eckhard Thines, Luis Antelo, Louis Pergaud Sandjo, Till Opatz
  • Patent number: 11064703
    Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: July 20, 2021
    Assignee: BASF SE
    Inventors: Isabella Siepe, Heike Brueser, Kristin Klappach, Karl-Heinrich Schneider, Petra Sproete, Kerstin Hage, Birgit Blanz, Eckhard Thines, Luis Antelo, Louis Pergaud Sandjo, Till Opatz
  • Publication number: 20200390092
    Abstract: The present invention provides lignin nanoparticles containing a hydrophobic active agent and a process for the production of the lignin nanoparticles. The process involves the following steps: (i) dissolving modified lignin and a hydrophobic active agent in an organic solvent having low solubility in water; (ii) combining the solution with water and a surfactant to form a pre-emulsion; (iii) forming an emulsion from the pre-emulsion; and (iv) crosslinking the modified lignin to form the lignin nanoparticles, in which the modified lignin is lignin which is chemically modified to contain at least two functional groups suitable for polymerization and/or crosslinking.
    Type: Application
    Filed: April 9, 2020
    Publication date: December 17, 2020
    Inventors: Frederik WURM, Katharina LANDFESTER, Doungporn YIAMSAWAS, Eckhard THINES, Jochen FISCHER
  • Patent number: 10548326
    Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: February 4, 2020
    Assignee: BASF SE
    Inventors: Isabella Siepe, Heike Brueser, Kristin Klappach, Karl-Heinrich Schneider, Petra Sproete, Kerstin Hage, Birgit Blanz, Eckhard Thines, Luis Antelo, Louis Pergaud Sandjo, Till Opatz
  • Patent number: 10240216
    Abstract: The present invention relates to fungal strains, which are a member of the genus Penicillium and have antifungal activity, and to cell-free extracts of said strains, culture media obtainable by culturing said strains and extrolites produced by said strains, all of which have fungicidal activity. The present invention further relates to compositions comprising said strains, extracts, culture media and extrolites, and their uses in the agrochemical field and the field of controlling phytopathogenic fungi in particular.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: March 26, 2019
    Assignee: BASF SE
    Inventors: Isabella Siepe, Thorsten Jabs, Anja Schueffler, Louis Pergaud Sandjo, Heidrun Anke, Eckhard Thines, Till Opatz
  • Publication number: 20190037837
    Abstract: The present invention provides lignin nanoparticles containing a hydrophobic active agent and a process for the production of the lignin nanoparticles. The process involves the following steps: (i) dissolving modified lignin and a hydrophobic active agent in an organic solvent having low solubility in water; (ii) combining the solution with water and a surfactant to form a pre-emulsion; (iii) forming an emulsion from the pre-emulsion; and (iv) crosslinking the modified lignin to form the lignin nanoparticles, in which the modified lignin is lignin which is chemically modified to contain at least two functional groups suitable for polymerization and/or crosslinking.
    Type: Application
    Filed: February 6, 2017
    Publication date: February 7, 2019
    Inventors: Frederik WURM, Katharina LANDFESTER, Doungporn YIAM-SAWAS, Eckhard THINES, Jochen FISCHER
  • Publication number: 20180127840
    Abstract: The present invention relates to fungal strains, which are a member of the genus Penicillium and have antifungal activity, and to cell-free extracts of said strains, culture media obtainable by culturing said strains and extrolites produced by said strains, all of which have fungicidal activity. The present invention further relates to compositions comprising said strains, extracts, culture media and extrolites, and their uses in the agrochemical field and the field of controlling phytopathogenic fungi in particular.
    Type: Application
    Filed: December 20, 2017
    Publication date: May 10, 2018
    Inventors: Isabella SIEPE, Thorsten JABS, Anja SCHUEFFLER, Louis Pergaud SANDJO, Heidrun ANKE, Eckhard THINES, Till OPATZ
  • Publication number: 20180020674
    Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.
    Type: Application
    Filed: October 4, 2017
    Publication date: January 25, 2018
    Inventors: Isabella SIEPE, Heike BRUESER, Kristin KLAPPACH, Karl-Heinrich SCHNEIDER, Petra SPROETE, Kerstin HAGE, Birgit BLANZ, Eckhard THINES, Luis ANTELO, Louis Pergaud SANDJO, Till OPATZ
  • Publication number: 20180020675
    Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.
    Type: Application
    Filed: October 4, 2017
    Publication date: January 25, 2018
    Inventors: Isabella SIEPE, Heike BRUESER, Kristin KLAPPACH, Karl-Heinrich SCHNEIDER, Petra SPROETE, Kerstin HAGE, Birgit BLANZ, Eckhard THINES, Luis ANTELO, Louis Pergaud SANDJO, Till OPATZ
  • Publication number: 20170223968
    Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens.
    Type: Application
    Filed: August 4, 2015
    Publication date: August 10, 2017
    Inventors: Isabella SIEPE, Heike BRUSER, Kristin KLAPPACH, Karl-Heinrich SCHNEIDER, Petra SPROTE, Kerstin HAGE, Birgit BLANZ, Eckhard THINES, Luis ANTELO, Louis Pergaud SANDJO, Till OPATZ
  • Publication number: 20160298201
    Abstract: The present invention relates to fungal strains, which are a member of the genus Penicillium and have antifungal activity, and to cell-free extracts of said strains, culture media obtainable by culturing said strains and extrolites produced by said strains, all of which have fungicidal activity. The present invention further relates to compositions comprising said strains, extracts, culture media and extrolites, and their uses in the agrochemical field and the field of controlling phytopathogenic fungi in particular.
    Type: Application
    Filed: November 10, 2014
    Publication date: October 13, 2016
    Inventors: Isabella SIEPE, Thorsten JABS, Anja SCHUEFFLER, Louis Pergaud SANDJO, Heidrun ANKE, Eckhard THINES, Till OPATZ