Patents by Inventor Ed STANLEY

Ed STANLEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vectors and methods for targeted integration in loci comprising constitutively expressed genes
    Patent number: 10745717
    Abstract: The invention relates to a vector comprising: a 5? nucleic acid that is homologous to a genomic sequence 5? of a stop codon of a constitutively expressed gene; an exogenous nucleic acid; a 3? nucleic acid that is homologous to a genomic sequence 3? of the stop codon of the constitutively expressed gene; a translation interruption-reinitiation signal operably linked to the 5? nucleic acid and the exogenous nucleic acid, wherein the translation interruption-reinitiation signal is capable of replacing the stop codon of the constitutively expressed gene.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: August 18, 2020
    Assignee: Murdoch Children's Research Institute
    Inventors: Ed Stanley, Andrew Elefanty, David Elliott, Tatiana Labonne
  • VECTORS AND METHODS FOR TARGETED INTEGRATION IN LOCI COMPRISING CONSTITUTIVELY EXPRESSED GENES
    Publication number: 20180057842
    Abstract: The invention relates to a vector comprising: a 5? nucleic acid that is homologous to a genomic sequence 5? of a stop codon of a constitutively expressed gene; an exogenous nucleic acid; a 3? nucleic acid that is homologous to a genomic sequence 3? of the stop codon of the constitutively expressed gene; a translation interruption-reinitiation signal operably linked to the 5? nucleic acid and the exogenous Targeting nucleic acid, wherein the translation interruption-reinitiation signal is capable of replacing the stop codon of the constitutively expressed gene.
    Type: Application
    Filed: November 10, 2015
    Publication date: March 1, 2018
    Inventors: Ed STANLEY, Andrew ELEFANTY, David ELLIOTT, Tatiana LABONNE