Patents by Inventor Edamanal S. Venkataramani

Edamanal S. Venkataramani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biodegradation of methanesulfonic acid
    Patent number: 6063280
    Abstract: A process is described for the acclimation and enrichment of an activated sludge culture for the degradation of high concentrations of methanesulfonic acid, so as to render it non-toxic to the aquatic environment.
    Type: Grant
    Filed: February 2, 1994
    Date of Patent: May 16, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Robert Boyle, Edamanal S. Venkataramani
  • Process for recovery and recycle of methanesulfonic acid and phosphorous acid
    Patent number: 5589691
    Abstract: Disclosed is a process for recovering and recycling waste methanesulfonic acid (MSA) and phosphorous acid (H.sub.3 PO.sub.3) in a bisphosphonation process for reuse in the process. The recovery process involves treating a waste crude mother liquor stream with HCl to remove sodium ion, as sodium chloride, recovering HCl--H.sub.2 O by atmospheric distillation, separating and dehydrating a mixture of methanesulfonic acid and phosphorous acid by vacuum distillation for recycle. The substantially dry methanesulfonic acid and phosphorous acid, and previous HCl, can all be recycled back to the process for reuse.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: December 31, 1996
    Assignee: Merck & Co., Inc.
    Inventors: Edamanal S. Venkataramani, Andrew L. Forman, Ralph J. Magliette, Jr., William A. Vaughn, Richard R. Dauer
  • Process for removing waste pox, alendronate and its by products
    Patent number: 5449819
    Abstract: Disclosed is a process for removing by-product phosphorus-containing (PO.sub.x) materials, alendronate and alendronate byproducts from crude mother liquors in an omega amino-1-hydroxy-C.sub.2 -C.sub.6 alkylidene-1,1-bisphosphonic acid synthesis process, e.g. alendronate sodium. Calcium chloride is added first to the crude mother liquors, then calcium oxide to precipitate the PO.sub.x materials, then neutralized to about pH 7 to complete precipitation. Substantially all of the alendronate sodium active ingredient is removed from the precipitate. Following filtration, the PO.sub.x filtercake can then be disposed of by incineration, landfilling or reclamation of usable phosphorus as fertilizer. The remaining filtrate can then be further treated in an environmentally acceptable manner by wastewater treatment or recycling to the process.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: September 12, 1995
    Assignee: Merck & Co., Inc.
    Inventors: Edamanal S. Venkataramani, Andrew L. Forman, Ralph J. Magliette, Jr., Donald McKinney
  • Biological process for producing 17.beta.-N-monosubstituted carbamoyl-11-oxo-4-aza-5-.alpha.-androst-3-one testosterone-5-.alpha. reductase inhibitors
    Patent number: 5215894
    Abstract: The present invention is concerned with a novel biotransformation process for producing 17.beta.-N-monosubstituted carbamoyl-11-oxo-4-aza-5-.alpha.-androst-3-ones of the formula: ##STR1## These compounds are testosterone 5-.alpha. reductase inhibitors and are produced via a claimed novel biotransformation process using the green algae, Selenastrum capricornutum.
    Type: Grant
    Filed: February 25, 1992
    Date of Patent: June 1, 1993
    Assignee: Merck & Co., Inc.
    Inventors: Byron H. Arison, Josephine R. Carlin, Edamanal S. Venkataramani