Abstract: Provided are methods for the identification of cancer-associated microbial features and applications thereof in diagnostics and therapeutic stratification.

Abstract: Provided are methods for creating a diagnostic model for determining a disease of a subject, methods to identify disease-associated metaepigenomic biomarkers and methods to employ these biomarkers to accurately diagnose certain diseases from a tissue or liquid biopsy sample, based on epigenetic data from the subject's genome and microbial genomes contained within that subject

Abstract: Methods and systems are presented herein for predicting a disease of a subject through a combination of fungal and non-fungal molecular analyte features of a biological sample.

Abstract: Provided are methods for isolating biomolecules, such as nucleic acids and proteins, from a sample using a silica-containing surface and/or a high salt, low pH buffer.

Abstract: Provided are methods and compositions for negatively and positively selecting for different size nucleic acid (e.g., DNA or RNA) fragments on borosilicate glass fiber membranes, silica and metal oxide surfaces such that only those fragments falling within a desired size range are obtained.

Abstract: Provided are methods for isolating biomolecules, such as nucleic acids and proteins, from a sample using a silica-containing surface and/or a high salt, low pH buffer.

Abstract: Provided, in part, are methods, compositions, and systems are provided for detecting one or more repellent-generating enzymatic pathways by characterizing the skin microbiomes and metabolomes of populations of individuals both naturally resistant and highly prone to bites from blood sucking arthropods, determining the microbial taxa (and their associated metabolic pathways) most associated with insect repellency and targeting/activating those pathways with molecular substrates that, when metabolized, will give rise, in situ, to repellent molecules and can promote a shift to a more naturally repellent microbiome composition.

Abstract: Provided are methods and compositions for negatively and positively selecting for different size nucleic acid (e.g., DNA or RNA) fragments on borosilicate glass fiber membranes, silica and metal oxide surfaces such that only those fragments falling within a desired size range are obtained.

Abstract: Provided, in part, are methods, compositions, and systems are provided for detecting one or more repellent-generating enzymatic pathways by characterizing the skin microbiomes and metabolomes of populations of individuals both naturally resistant and highly prone to bites from blood sucking arthropods, determining the microbial taxa (and their associated metabolic pathways) most associated with insect repellency and targeting/activating those pathways with molecular substrates that, when metabolized, will give rise, in situ, to repellent molecules and can promote a shift to a more naturally repellent microbiome composition.

Abstract: A clamp for establishing an electrical connection with a conductor is provided. The clamp comprises a first body and a second body. The second body is pivotally coupled to the first body. The first and second bodies define a receiving region therebetween for receiving a conductor. The first and second bodies are biased towards each other at the receiving region to clamp a conductor. The clamp also comprises a shutter, movably coupled to one of the first body and the second body. The shutter is biased into a restricting position in which entry into the receiving region is restricted.

Abstract: The present invention generally relates to compositions comprising antigen-carbohydrate conjugates and methods of immune modulation featuring these reagents.

Abstract: The present invention generally relates to compositions comprising antigen-carbohydrate conjugates and methods of immune modulation featuring these reagents.

Abstract: One aspect of the present invention relates to an array, comprising a plurality of spots on a solid support, wherein each spot independently comprises a substrate attached to said solid support, wherein each substrate attached to said solid support is independently a carbohydrate-containing molecule. A second aspect of the present invention relates to a method of preparing such an array of carbohydrate-containing molecules. A third aspect of the present invention relates to a method to detect the interaction of a carbohydrate with a binding molecule.

Abstract: An invasive electrical stimulation device includes a cathode an anode, each comprising a thin electrically conductive sheet having one exposed surface and the opposite surface covered with an insulation layer. A pair of insulated leads connect the cathode and anode to an implantable power pac which includes a source of electric power and an insulating encasement surrounding the same. The cathode may be equipped with a plurality of spaced-apart FM channel monitors which are electrically connected to an FM telemetry component within the power pac for transmitting signals indicative of the healing response of a fracture to electrical stimulation. A frequency modulated current regulator may be added to the power pac for adjusting the amperage in response to FM control signals from a remote transmitter or automatically by an implantable computer assisted device.