Patents by Inventor Eddie H. Massey

Eddie H. Massey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized insulin formulations
    Patent number: 4839341
    Abstract: This invention provides an insulin formulation stabilized against aggregation containing a hydroxybenzene and a polyethylene glycol-polypropylene glycol polymer of the formula ##STR1## having an average molecular weight of about 8350 and in which the average number of ethyleneoxy units per molecule, designated by the sum of a and c, is about 150, and the average number of propyleneoxy units per molecule, designated as b, is about 30.
    Type: Grant
    Filed: November 13, 1987
    Date of Patent: June 13, 1989
    Assignee: Eli Lilly and Company
    Inventors: Eddie H. Massey, Theodore A. Sheliga
  • Crystalline human proinsulin and process for its production
    Patent number: 4764592
    Abstract: This disclosure provides a crystalline human proinsulin, the preparation of which comprises(a) preparing an aqueous mixture containing from about 5 to about 50 mg/ml human proinsulin, from about 0.1 to about 5 mg/ml of a phenolic substance, from about 0.03 to about 0.6 milliequivalents/ml of a salt of a cation selected from the group consisting of lithium, calcium, sodium, potassium, ammonium, magnesium, and barium, and from about 0.2 to about 5 milliequivalents of Zn.sup.+2 cation;(b) adjusting the aqueous mixture to a pH in the range of from about 5.4 to about 6.5;(c) allowing crystal formation to occur; and(d) recovering crystalline human proinsulin from the aqueous mixture.
    Type: Grant
    Filed: April 23, 1987
    Date of Patent: August 16, 1988
    Assignee: Eli Lilly and Company
    Inventors: Eddie H. Massey, Richard L. Jackson
  • Soluble dobutamine salts
    Patent number: 4704407
    Abstract: Hydroxyalkanoic or alkandioic acid salts of dobutamine having desirable water solubility, useful in preparing intravenous solution for treatment of cardiogenic shock.
    Type: Grant
    Filed: October 3, 1986
    Date of Patent: November 3, 1987
    Assignee: Eli Lilly and Company
    Inventor: Eddie H. Massey