Abstract: A method for treating and preventing neurodegenerative diseases, a method of reversing cognitive and memory deficit, a method of decreasing A? level and hyperphosphorylated Tau in a subject in need thereof with histamine antagonists, glucocorticoid, or their combinations includes the step of administrating a histamine H4 receptor antagonist or a glucocorticoid, or their combination to the subject.

Abstract: Provided herein are methods of treating a nervous system injury, such as a central nervous system injury and/or a peripheral nervous system injury, and methods for treating an injured neuron using glycopyrrolate, mexiletine, or a mixture thereof.

Abstract: A drug screening method uses electroencephalogram (EEG) or electromyogram (EMG) data applied to a ML model. EEG or EMG data is measured from a first animal species during administration of a seizure-inducing agent. A ML model is trained with the first animal species EEG or EMG data as well as measured EEG or EMG from a second animal species such that the trained ML model is able to identify a neurological adverse event in the second animal species based on data from the first animal species. A potential drug candidate is screened by administering the potential drug candidate to the first animal species and measuring the EEG or EMG data of the first animal species during the potential drug candidate administration. The measured EEG or EMG data is applied to the ML model to determine whether there is the neurological adverse event associated with the drug candidate administration.

Abstract: A neurostimulation system includes an electromyographic (EMG) electrode; a neural electrode implantable in a deep cerebellar nuclei of a subject; a data acquisition unit in communication with the EMG electrode for receiving and transmitting a EMG signal; and a processor in communication with the data acquisition unit, the processor generates a EMG pattern based on the EMG signal and outputs a stimulation signal to the neural electrode when the EMG pattern is indicative of an abnormal motor movement. A method of modulating an abnormal motor movement of a subject by using the neurostimulation system.

Abstract: A resource management system for a virtual machine computing environment includes a software component that optimizes capacity between server clusters or groups by monitoring the capacity of server clusters or groups and automatically adding and removing host systems to and from server clusters or groups. The software component may be implemented at a server cluster management level to monitor and execute host system moves between server clusters and/or at a higher level in the resource management hierarchy. At the higher level, the software component is configured to monitor and execute host system moves between sets of server clusters being managed by different server cluster management agents.

Abstract: Provided herein is a method of treating a traumatic brain injury in a subject in need thereof, the method including administering to the subject a therapeutically effective amount of radiation. The methods can improve motor function recovery and reverse motor function deficits after traumatic brain injury and/or ischemic stroke in a subject.

Abstract: Provided herein are methods of treating a nerve injury in a subject in need thereof and methods of treating an injured neuron using diaryl hydrazones.

Abstract: Provided herein are methods of treating a nervous system injury, such as a central nervous system injury and/or a peripheral nervous system injury, and methods for treating an injured neuron using glycopyrrolate, mexiletine, or a mixture thereof.

Abstract: Systems and methods are described which determine, in real time, and without impeding the natural flow of vehicles, which vehicles entering a predetermined area is there for commercial purposes, and designate a charge for the commercial purpose.

Abstract: A neurostimulation system includes an electromyographic (EMG) electrode; a neural electrode implantable in a deep cerebellar nuclei of a subject; a data acquisition unit in communication with the EMG electrode for receiving and transmitting a EMG signal; and a processor in communication with the data acquisition unit, the processor generates a EMG pattern based on the EMG signal and outputs a stimulation signal to the neural electrode when the EMG pattern is indicative of an abnormal motor movement. A method of modulating an abnormal motor movement of a subject by using said neurostimulation system.

Abstract: A resource management system for a virtual machine computing environment includes a software component that optimizes capacity between server clusters or groups by monitoring the capacity of server clusters or groups and automatically adding and removing host systems to and from server clusters or groups. The software component may be implemented at a server cluster management level to monitor and execute host system moves between server clusters and/or at a higher level in the resource management hierarchy. At the higher level, the software component is configured to monitor and execute host system moves between sets of server clusters being managed by different server cluster management agents.

Abstract: A resource management system for a virtual machine computing environment includes a software component that optimizes capacity between server clusters or groups by monitoring the capacity of server clusters or groups and automatically adding and removing host systems to and from server clusters or groups. The software component may be implemented at a server cluster management level to monitor and execute host system moves between server clusters and/or at a higher level in the resource management hierarchy. At the higher level, the software component is configured to monitor and execute host system moves between sets of server clusters being managed by different server cluster management agents.

Abstract: A method for restarting a virtual machine in a virtual computing system having a plurality of hosts and a resource scheduler for the plurality of hosts includes writing a placement request for the virtual machine to a shared channel that is accessible by the resource scheduler. The method further includes reading a placement result from the shared channel, wherein the placement result is generated by the resource scheduler responsive to the placement request; and restarting the virtual machine in accordance with the placement result.

Abstract: A resource management system for a virtual machine computing environment includes a software component that optimizes capacity between server clusters or groups by monitoring the capacity of server clusters or groups and automatically adding and removing host systems to and from server clusters or groups. The software component may be implemented at a server cluster management level to monitor and execute host system moves between server clusters and/or at a higher level in the resource management hierarchy. At the higher level, the software component is configured to monitor and execute host system moves between sets of server clusters being managed by different server cluster management agents.

Abstract: A resource management system for a virtual machine computing environment includes a software component that optimizes capacity between server clusters or groups by monitoring the capacity of server clusters or groups and automatically adding and removing host systems to and from server clusters or groups. The software component may be implemented at a server cluster management level to monitor and execute host system moves between server clusters and/or at a higher level in the resource management hierarchy. At the higher level, the software component is configured to monitor and execute host system moves between sets of server clusters being managed by different server cluster management agents.

Abstract: A method for restarting a virtual machine in a virtual computing system having a plurality of hosts and a resource scheduler for the plurality of hosts includes writing a placement request for the virtual machine to a shared channel that is accessible by the resource scheduler. The method further includes reading a placement result from the shared channel, wherein the placement result is generated by the resource scheduler responsive to the placement request; and restarting the virtual machine in accordance with the placement result.

Abstract: A resource management system for a virtual machine computing environment includes a software component that optimizes capacity between server clusters or groups by monitoring the capacity of server clusters or groups and automatically adding and removing host systems to and from server clusters or groups. The software component may be implemented at a server cluster management level to monitor and execute host system moves between server clusters and/or at a higher level in the resource management hierarchy. At the higher level, the software component is configured to monitor and execute host system moves between sets of server clusters being managed by different server cluster management agents.