Patents by Inventor Edgar Schmitt

Edgar Schmitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210130489
    Abstract: The present invention relates to a compound comprising a first polypeptide sequence comprising at least three different amino acid sequences selected from the group consisting of GFTFSDYW (SEQ ID NO: 1), IRLKSNNYAA (SEQ ID NO: 2) and TFGNSFAY (SEQ ID NO: 3), a second polypeptide sequence comprising at least three different amino acid sequences selected from the group consisting of TGAVTTNNY (SEQ ID NO: 4), GTN (SEQ ID NO: 5) and ALWYSNHWV (SEQ ID NO: 6), or a variant of any one of said amino acid sequences of SEQ ID NO: 1 to SEQ ID NO: 6 having a different amino acid at one position, wherein said compound or variant is capable of binding to tumour-associated Mucin-1 (TA-MUC1).
    Type: Application
    Filed: March 18, 2019
    Publication date: May 6, 2021
    Inventors: Edgar Schmitt, Horst Kunz, Natascha Stergiou, Nikola Gaidzik
  • Publication number: 20200316167
    Abstract: The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 8, 2020
    Inventors: Franz-Josef Schneider, Christian Becker, Tobias Bopp, Helmut Jonuleit, Edgar Schmitt
  • Patent number: 10729742
    Abstract: The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: August 4, 2020
    Assignee: Universitätsmedizin Der Johannes Gutenberg-Universität Mainz
    Inventors: Franz-Josef Schneider, Christian Becker, Tobias Bopp, Helmut Jonuleit, Edgar Schmitt
  • Publication number: 20170014474
    Abstract: The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.
    Type: Application
    Filed: October 5, 2016
    Publication date: January 19, 2017
    Inventors: Franz-Josef Schneider, Christian Becker, Tobias Bopp, Helmut Jonuleit, Edgar Schmitt
  • Patent number: 9534944
    Abstract: A method for determining and/or monitoring fill level of a medium in a container with a measuring device, which works according to the travel time measuring method, wherein measurement signals are transmitted toward the medium and are received, wherein from the high-frequency total measurement signal, composed by superimposing the transmitted measurement signals, the reflected wanted echo signals and the disturbance echo signals, a raw echo curve or digitized envelope curve is ascertained. The wanted echo signals and/or the disturbance echo signals in the raw echo curve or the digitized envelope curve are ascertained based on an ideal echo curve, which shows the amplitude of the echo signals of an ideal reflector as a function of the distance from the ideal reflector, and based on the ascertained wanted echo signal the fill level is determined.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: January 3, 2017
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Alexey Malinovskiy, I, Stefan Gorenflo, Dietmar Spanke, Edgar Schmitt
  • Patent number: 9442000
    Abstract: A method for ascertaining and monitoring fill level of a medium in a container using a travel time measuring method, wherein transmission signals are transmitted toward the medium and reflection signals are received. The received reflection signals are registered as echo signals in an echo function dependent on travel time. Based on known measuring device- and container-specific reflection planes, possible reflection regions in the echo function are calculated by means of an evaluation algorithm. In the calculated reflection regions, the disturbance echo signals and/or the multiecho signals in the echo function are classified, wherein non-classified reflection signals are ascertained and checked as wanted echo signals by means of a search algorithm, wherein, from a position and/or an amplitude of at least one wanted echo signal, fill level is determined, and wherein the measured value of fill level is output.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: September 13, 2016
    Assignee: ENDRESS + HAUSER GMBH + CO. KG
    Inventors: Edgar Schmitt, Dietmar Spanke, Alexey Malinovskiy, Stefan Gorenflo, Klaus Feisst
  • Publication number: 20150192449
    Abstract: A method for determining and/or monitoring fill level of a medium in a container with a measuring device, which works according to the travel time measuring method, wherein measurement signals are transmitted toward the medium and are received, wherein from the high-frequency total measurement signal, composed by superimposing the transmitted measurement signals, the reflected wanted echo signals and the disturbance echo signals, a raw echo curve or digitized envelope curve is ascertained. The wanted echo signals and/or the disturbance echo signals in the raw echo curve or the digitized envelope curve are ascertained based on an ideal echo curve, which shows the amplitude of the echo signals of an ideal reflector as a function of the distance from the ideal reflector, and based on the ascertained wanted echo signal the fill level is determined.
    Type: Application
    Filed: July 26, 2013
    Publication date: July 9, 2015
    Applicant: Endress + Hauser GmbH + Co. KG
    Inventors: Alexey Malinovskiy, I, Stefan Gorenflo, Dietmar Spanke, Edgar Schmitt
  • Publication number: 20140093509
    Abstract: The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.
    Type: Application
    Filed: September 19, 2013
    Publication date: April 3, 2014
    Applicant: TCF GMBH
    Inventors: Franz-Josef Schneider, Christian Becker, Tobias Bopp, Helmut Jonuleit, Edgar Schmitt
  • Patent number: 8639457
    Abstract: A method for ascertaining and monitoring the fill level of a medium in a container via a field device, wherein transmission signals are transmitted toward the medium and are received as reflection signals. The transmission signals and the reflection signals are registered by means of data points in an envelope curve dependent on travel time or travel distance. Disturbance echo signals are registered by means of data points in a masking curve, the data points are connected with one another via connecting functions An evaluation curve is ascertained from the envelope curve; wherein, by means of a reduction algorithm, the number of data points in the masking curve and/or in the evaluation curve is reduced; and wherein, by an echo search algorithm, by means of the reduced masking curve and/or reduced evaluation curve, at least one wanted echo signal in the current envelope curve is ascertained.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: January 28, 2014
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Manfred Hammer, Alexey Malinovskiy, Edgar Schmitt, Herbert Schroth, Dietmar Spanke
  • Patent number: 8557533
    Abstract: The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: October 15, 2013
    Inventors: Franz-Josef Schneider, Christian Becker, Tobias Bopp, Helmut Jonuleit, Edgar Schmitt
  • Publication number: 20130207836
    Abstract: A method for ascertaining and monitoring fill level of a medium in a container using a travel time measuring method, wherein transmission signals are transmitted toward the medium and reflection signals are received. The received reflection signals are registered as echo signals in an echo function dependent on travel time. Based on known measuring device- and container-specific reflection planes, possible reflection regions in the echo function are calculated by means of an evaluation algorithm. In the calculated reflection regions, the disturbance echo signals and/or the multiecho signals in the echo function are classified, wherein non-classified reflection signals are ascertained and checked as wanted echo signals by means of a search algorithm, wherein, from a position and/or an amplitude of at least one wanted echo signal, fill level is determined, and wherein the measured value of fill level is output.
    Type: Application
    Filed: August 29, 2011
    Publication date: August 15, 2013
    Inventors: Edgar Schmitt, Dietmar Spanke
  • Patent number: 8276444
    Abstract: A method for ascertaining and monitoring fill level of a medium in a container a field device using a travel time, measuring method, wherein transmission signals are transmitted and reflection signals received. The received reflection signals are registered as echo signals in an echo function, wherein masking curve, evaluation curves and/or echo parameters of the echo signals in the echo function are ascertained or predetermined, as well as stored in a first measuring cycle. By a static echo search algorithm, through the masking curve, the evaluation curve, the echo parameters, position and/or amplitude of at least one wanted echo signal are/is ascertained, wherein, a dynamic echo search algorithm, a continuous echo tracking of positional changes and/or amplitude changes of individual echo signals and/or the wanted echo signal in the echo function is performed.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: October 2, 2012
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Alexey Malinovskiy, Edgar Schmitt, Dietmar Spanke
  • Patent number: 8159386
    Abstract: A method for ascertaining and monitoring fill level of a medium in a container by means of a field device by a travel time measuring method, wherein transmission signals are transmitted in the direction of the medium and reflection signals are received, wherein received reflection signals are registered as echo signals in an echo function dependent on travel time or travel distance, wherein position and/or amplitude at least of a wanted echo signal in the echo function are/is ascertained by means of an echo search algorithm and a continuous echo tracking of changes of position and/or of changes of amplitude of the wanted echo signal in the echo function is performed in a defined search window, wherein position and/or amplitude at least of a wanted echo signal is maintained, in case no wanted echo signal is ascertained in the search window, wherein from position and/or amplitude at least of a wanted echo signal, fill level is ascertained, and wherein a measured value of fill level is output.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: April 17, 2012
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Alexey Malinovskiy, Dietmar Spanke, Edgar Schmitt, Steffen Markoni, Simon Greth, Klaus Pankratz, Stefan Gorenflo
  • Publication number: 20110166805
    Abstract: A method for ascertaining and monitoring the fill level of a medium in a container via a field device, wherein transmission signals are transmitted toward the medium and are received as reflection signals. The transmission signals and the reflection signals are registered by means of data points in an envelope curve dependent on travel time or travel distance. Disturbance echo signals are registered by means of data points in a masking curve, the data points are connected with one another via connecting functions An evaluation curve is ascertained from the envelope curve; wherein, by means of a reduction algorithm, the number of data points in the masking curve and/or in the evaluation curve is reduced; and wherein, by an echo search algorithm, by means of the reduced masking curve and/or reduced evaluation curve, at least one wanted echo signal in the current envelope curve is ascertained.
    Type: Application
    Filed: August 11, 2008
    Publication date: July 7, 2011
    Applicant: Endress + Hauser GmbH + Co. KG
    Inventors: Manfred Hammer, Alexey Malinovskiy, Edgar Schmitt, Herbert Schroth, Dietmar Spanke
  • Patent number: 7966141
    Abstract: An improved and more accurate method for evaluating and correcting total measurement signals (TS(n)) of measuring devices. The invention concerns a method for evaluating and correcting total measurement signals (TS(n)) of a measuring device, wherein measuring signals are transmitted in the direction of a medium and reflected on a surface of the medium as wanted echo signals or on a surface of a disturbing element as interference signals and received. In the case of a modification of at least one technical, process condition in the container and/or a modification of at least one technical, measurement condition of the measuring device, an independent reference curve is ascertained on the basis of a current static reference curve, wherein the interference signals are masked out of the raw echo curve on the basis of a masking algorithm, which applies the independent reference curve.
    Type: Grant
    Filed: November 9, 2005
    Date of Patent: June 21, 2011
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Dietmar Spanke, Edgar Schmitt, Holger Steltner, Alexey Malinovskiy
  • Patent number: 7826309
    Abstract: A method for measuring a fill level of a fill substance in a container and for monitoring at least one predetermined fill level (LMIN, LMAX), using a fill level measuring device working according to the travel-time principle, as well as a corresponding fill level measuring device, wherein the monitoring satisfies high safety standards, wherein, in each measuring cycle, transmission signals (S) are sent toward the fill substance and their echo signals (E) are received, the fill level is determined, based on the echo signals (E), in a first evaluation method, and it is determined, based on the echo signals (E), in a second evaluation method independent of the first evaluation method, whether the fill level exceeds or falls beneath the predetermined fill levels (LMIN, LMAX).
    Type: Grant
    Filed: December 14, 2004
    Date of Patent: November 2, 2010
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Dietmar Spanke, Edgar Schmitt, Reinhard Schaefer, Holger Steltner
  • Patent number: 7819002
    Abstract: A reliable method for measuring a fill level of a fill substance in a container using a fill level measuring device working according to the travel-time principle, wherein, periodically, transmission signals are sent in the direction of the fill substance, their echo signals are registered and converted into an echo function, at least one echo characteristic of the echo function is determined and, on the basis of the echo characteristics of at least one preceding measurement, a prediction is derived for the echo characteristics to be expected in the case of the current measurement, the echo characteristics of the current measurement are determined taking into consideration the prediction, and, on the basis of the echo characteristics, the current fill level is determined.
    Type: Grant
    Filed: December 14, 2004
    Date of Patent: October 26, 2010
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Dietmar Spanke, Marc Baret, Edgar Schmitt, Yong Jin
  • Publication number: 20100182190
    Abstract: A method for ascertaining and monitoring fill level of a medium in a container by means of a field device by a travel time measuring method, wherein transmission signals are transmitted in the direction of the medium and reflection signals are received, wherein received reflection signals are registered as echo signals in an echo function dependent on travel time or travel distance, wherein position and/or amplitude at least of a wanted echo signal in the echo function are/is ascertained by means of an echo search algorithm and a continuous echo tracking of changes of position and/or of changes of amplitude of the wanted echo signal in the echo function is performed in a defined search window, wherein position and/or amplitude at least of a wanted echo signal is maintained, in case no wanted echo signal is ascertained in the search window, wherein from position and/or amplitude at least of a wanted echo signal, fill level is ascertained, and wherein a measured value of fill level is output.
    Type: Application
    Filed: December 29, 2009
    Publication date: July 22, 2010
    Applicant: Endress + Hauser GmbH + Co. KG
    Inventors: Dietmar Spanke, Klaus Pankratz, Edgar Schmitt, Alexey Malinovskiy, Stefan Gorenflo, Simon Greth, Steffen Markoni
  • Publication number: 20100162811
    Abstract: A method for ascertaining and monitoring fill level of a medium in a container by means of a field device using a travel time, measuring method, wherein transmission signals are transmitted and reflection signals received. The received reflection signals are registered as echo signals in an echo function, wherein masking curve, evaluation curves and/or echo parameters of the echo signals in the echo function are ascertained or predetermined, as well as stored in a first measuring cycle. By means of a static echo search algorithm, through the masking curve, the evaluation curve, the echo parameters, position and/or amplitude of at least one wanted echo signal are/is ascertained, wherein, by means of a dynamic echo search algorithm, a continuous echo tracking of positional changes and/or amplitude changes of individual echo signals and/or the wanted echo signal in the echo function is performed.
    Type: Application
    Filed: December 19, 2007
    Publication date: July 1, 2010
    Applicant: ENDRESS + HAUSER SMBH + CO. KG
    Inventors: Alexey Malinovskiy, Edgar Schmitt, Dietmar Spanke
  • Publication number: 20100074904
    Abstract: The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.
    Type: Application
    Filed: January 30, 2008
    Publication date: March 25, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Franz-Josef Schneider, Christian Becker, Tobias Bopp, Helmut Jonuleit, Edgar Schmitt