Patents by Inventor Edit Berenyi
Edit Berenyi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4921861Abstract: The 3-amino-4-ethylthio-quinoline of the Formula I ##STR1## and pharmaceutically acceptable acid addition salts thereof possess useful therapeutical properties. They exhibit a potent and highly selective anxiolytic and narcosis potentiating effect and are devoid of sedative and anti-convulsive effect. Consequently, the invention relates to pharmaceutical compositions comprising the compound of Formula I or a salt thereof as active agent.The invention also relates to a new and improved process for the preparation of the compound of Formula I.Type: GrantFiled: April 22, 1988Date of Patent: May 1, 1990Assignee: BASF AktiengesellschaftInventors: Jozsef Knoll, ne Simonyi Budai, Edit Berenyi ne Poldermann, Ildiko Miklya, Marton Fekete, Gabriella Zsilla, Berta Knoll, Attila Mandi, Lujza Petocz, Istvan Gyertyan, Istvan Gacsalyi
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Patent number: 4921960Abstract: The new compounds of the general Formula I ##STR1## (wherein R.sub.1 stands for C.sub.1-5 alkyl, C.sub.2-5 alkenyl, C.sub.2-5 alkinyl, C.sub.3-7 cycloalkyl or optionally substituted phenyl-(C.sub.1-4 alkyl);R.sub.2 represents hydrogen or C.sub.1-5 alkanoyl;X.sub.1 and X.sub.2 can be identical or different and each stands for hydrogen, halogen, trifluoromethyl or C.sub.1-4 alkoxy;(with the proviso that if R.sub.1 stands for ethyl, at least one of R.sub.2, X.sub.1 and X.sub.2 is different from hydrogen) and pharmaceutically acceptable acid additions salts possess valuable anxiolytic properties devoid of sedative effect and can be used in therapy.The compounds of the general Formula I can be prepared by methods known per se.Type: GrantFiled: April 22, 1988Date of Patent: May 1, 1990Assignee: BASF AktiengesellschaftInventors: Jozsef Knoll, Katalin Budai nee Simonyi, Edit Berenyi nee Poldermann, Ildiko Miklya, Marton Fekete, Gabriella Zsilla, Berta Knoll, Attila Mandi, Lujza Petocz, Istvan Gyertyan, Istvan Gacsalyi
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Patent number: 4904669Abstract: The invention relates to new thiazolo[4,5-c]quinoline derivatives of the general Formula I ##STR1## and acid addition salts thereof, a process for the preparation of the same and pharmaceutical compositions comprising the said compounds.The substituent definition of the general Formula I is as follows:R stands for hydrogen; a straight or branched chained alkyl group having 2-5 carbon atoms optionally substituted by one or more halogen atom(s); phenyl or phenyl-(lower alkyl) optionally bearing one or more substituent(s) on the phenyl ring;R.sup.1 and R.sup.2 are identical or different and stand for hydrogen, halogen or lower alkyl).The compounds of the general Formula I possess valuable central nervous depressive properties.Type: GrantFiled: November 12, 1986Date of Patent: February 27, 1990Assignee: EGIS GyogyszergyarInventors: Jozsef Knoll, Edit Berenyi nee Poldermann, Katain Budainee Simonyi, Berta Knoll, Zsuzsa Furts, Julia Timar, Gabriella Zsila, Ildiko Niklya, Lujza Petocz, Attila Mandi
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Patent number: 4883907Abstract: The present invention relates to new carbazates of the formula (I) ##STR1## wherein A is C.sub.3 to C.sub.10 alkenyl, C.sub.2 to C.sub.10 haloalkyl, trifluoromethyl, phenyl-C.sub.1 to C.sub.3 alkyl, phenyl-C.sub.2 to C.sub.3 alkenyl, naphthyl-C.sub.1 to C.sub.3 alkyl, C.sub.3 to C.sub.7 cycloalkyl-C.sub.1 to C.sub.3 alkyl, furyl which can be nitro-substituted, diphenyl-hydroxymethyl or indazolyl which can be substituted by one or more C.sub.1 to C.sub.4 alkoxy groups; andR is C.sub.1 to C.sub.4 alkyl,and acid addition salts thereof, a process for the preparation thereof and feed additives comprising the same.The compounds of formula (I) may be used in animal husbandry due to their weight-gain increasing and fodder utilization improving effect.Type: GrantFiled: April 11, 1988Date of Patent: November 28, 1989Assignee: Egis GyogyszergyarInventors: Ildiko Ratz nee Simonek, Pal Benko, Edit Berenyi nee Foldermann, Karoly Magyar
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Patent number: 4778811Abstract: It has been found that 2-methyl-thiazolo[4,5-c]quinoline and pharmaceutically acceptable acid addition salts and hydrates thereof possess valuable central nervous depressive properties being different from those of benzodiazepines. The invention relates to pharmaceutical compositions comprising as active ingredient 2-methyl-thiazolo[4,5-c]quinoline of the Formula I ##STR1## or a pharmaceutically acceptable acid addition salt or hydrate thereof.Type: GrantFiled: November 12, 1986Date of Patent: October 18, 1988Assignee: EGIS GyogyszergyarInventors: Jozsef Knoll, Lujza Petocz, Attila Mandi, Edit Berenyi nee Poldermann, Katalin Budai nee Simonyi, Berta Knoll, Zsuzsa Furts, Julia Timar, Gabriella Zsila, Ildiko Niklya
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Patent number: 4665083Abstract: The invention relates to novel iminothiazolidine derivatives of the formula (I), ##STR1## wherein R.sup.1 and R.sup.3 represent, independently from each other, hydrogen or lower alkyl group,R.sup.3 is nitro or amino group,R stands for halo, lower alkyl, haloalkyl, nitro, amino, hydroxy, lower alkoxy, carboxy or lower alkoxycarbonyl group, andn is 0, 1 or 2,and pharmaceutically acceptable acid addition salts thereof.The iminothiazolidine derivatives of the formula (I) possess valuable antidepressant, antiparkinsonic, antiepileptic and spasmolytic activities.Type: GrantFiled: April 25, 1985Date of Patent: May 12, 1987Assignee: Egis GyogyszergyarInventors: Karoly Lempert, Gyula Hornyak, Ferenc Bartha, Gabor Doleschall, Jozsef Fetter, Jozsef Nyitrai, Gyula Simig, Karoly Zauer, Peter Huszthy, Antal Feller, Lujza Petocz, Eniko Szirt, Katalin Grasser, Edit Berenyi, Zsuzsanna Orr, Etelka Pjeczka
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Patent number: 4652562Abstract: The invention relates to new quinoline derivatives of the general Formula I ##STR1## (wherein X stands for hydrogen, halogen or lower alkoxy;n is an integer of 1, 2 or 3;R.sup.1 represents hydrogen andR.sup.2 represents hydroxy-lower alkyl or lower alkoxy-lower alkyl or a group of the general formula IV, ##STR2## wherein Z stands for --O--, --S--, --NH-- or --N(lower alkyl)--; the dotted lines represent optional bonds; andm is 0 or 1; orR.sup.1 and R.sup.2 together with the adjacent nitrogen atom, they are attached to, form a 5- or 6-membered heterocyclic group which may optionally contain a further oxygen, nitrogen or sulfur heteroatom and may be optionally substituted),and pharmaceutically acceptable acid addition salts thereof. The new compounds of the present invention exhibit radiosensitizing effect, make hypoxial cells highly sensitive towards radiation and may be used in radiation therapy.Type: GrantFiled: June 4, 1986Date of Patent: March 24, 1987Assignee: Egis GyogyszergyarInventors: Edit Berenyi nee Poldermann, Laszlo Varga, Laszlo Pallos, Lujza Petocz, Laszlo Ladanyi, Peter Tompe, Eva Hartai nee Zsorzs, Agnes Kovacs nee Palotai
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Patent number: 4530923Abstract: The invention relates to new cyclic imines of the general formula (I), ##STR1## wherein A represents carbonyl or hydroxymethylene,B is oxygen or imino,R stands for hydrogen or lower alkyl,X.sub.1 and X.sub.2 may be the same or different and represent hydrogen, halogen, lower alkyl or alkoxy, amino or nitro,n is 6 or 7, andm is 0 or 1,and pharmaceutically acceptable acid addition salts and quaternary salts thereof. The invention relates further to a process for the preparation of said compounds, to pharmaceutical compositions containing said compounds as the active ingredient and to a process for the preparation of said pharmaceutical compositions.The cyclic imine derivatives of the invention possess valuable antiarrhythmic properties and can be used to advantage in the treatment of cardiovascular diseases.Type: GrantFiled: October 20, 1982Date of Patent: July 23, 1985Assignee: Egyt Gyogyszervegyeszeti GyarInventors: Jozsef Rakoczi, Edit Berenyi nee Poldermann, Bela Fekete, Laszlo Szekeres, Gyula Papp, Eva Keszthelyi nee Udvary
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Patent number: 4342766Abstract: New compounds are disclosed of the formulae ##STR1## or pharmaceutically effective salts thereof, wherein R is hydrogen, C.sub.1-12 alkyl, or R is phenyl or phenyl-C.sub.1 to C.sub.4 alkyl wherein the phenyl can be substituted with 1 to 3 halogen, C.sub.1 to C.sub.4 alkyl, or C.sub.1 to C.sub.4 alkoxy substituents; andX.sub.1, X.sub.2 and X.sub.3 are hydrogen, C.sub.1 to C.sub.6 alkanoyl, or C.sub.1 to C.sub.6 haloalkanoyl; and where X.sub.1 is hydrogen, X.sub.2 and X.sub.3 are not simultaneously hydrogen. The compounds possess antiphlogistic, analgesic, anticonvulsive, or tranquilizing properties.Type: GrantFiled: April 16, 1981Date of Patent: August 3, 1982Assignee: Egyt Gyogyszervegyeszeti GyarInventors: Edit Berenyi nee Poldermann, Peter Gorog, Katalin Grasser, Ibolya Kosoczky, Agnes Koracs nee Palotay, Lujza Petocz
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Patent number: 4303660Abstract: The invention relates to novel pyrazolo[1,5-c]quinazoline derivatives of the general formula I ##STR1## wherein R represents a hydrogen atom, a C.sub.1-4 alkyl group or an acyl group,R.sub.1 represents a hydrogen atom, a C.sub.1-12 alkyl group, a C.sub.3-8 cycloalkyl group, a C.sub.2-4 alkenyl group, an aralkyl group, wherein the alkyl group has 1 to 4 carbon atoms, a phenylalkenyl group, wherein the alkenyl group has 2 to 4 carbon atoms, furthermore a carboxy group or a phenyl group optionally substituted by one or more substituents selected from the group consisting of halogen, hydroxy, C.sub.1-4 alkoxy, nitro or di(C.sub.1-4 alkyl)amino groups, orR and R.sub.1 may form together a valence bond,R.sub.2 represents a hydrogen atom, a C.sub.1-4 alkyl or a phenyl group, orR.sub.1 and R.sub.2 may form together a C.sub.2-7 alkylene group,R.sub.Type: GrantFiled: May 16, 1980Date of Patent: December 1, 1981Assignee: Egyt Gyogyszervegyeszeti GyarInventors: Edit Berenyi nee Poldermann, Eniko Szirt nee Kiszelly, Peter Gorog, Lujza Petocz, Ibolya Kosoczky, Agnes Kovacs nee Palotai, Gabriella rmos nee Lassu