Patents by Inventor Edith Cerbelaud

Edith Cerbelaud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enantioselective amidases and uses thereof
    Patent number: 5766918
    Abstract: The present invention concerns polypeptides that possess an enantioselective amidase activity. It also concerns the genetic material required for the expression of these polypeptides as well as a microbiological procedure for their preparation. Finally, this invention concerns the utilization of these polypeptides and of transformed microorganisms for the enantioselective synthesis of acids from racemic amides, and in particular propionic acids, especially (S)-2-aryl-propionamide.
    Type: Grant
    Filed: October 5, 1995
    Date of Patent: June 16, 1998
    Assignee: Rhone-Poulenc Sante
    Inventors: Dominique Petre, Edith Cerbelaud, Jean-Fran.cedilla.ois Mayaux, Patrice Yeh
  • Enantioselective amidases, DNA sequences encoding them, method of preparation and utilization
    Patent number: 5260208
    Abstract: The present invention concerns a DNA sequence coding for a polypeptide with enantioselective amidase activity.
    Type: Grant
    Filed: November 14, 1990
    Date of Patent: November 9, 1993
    Assignee: Rhone-Poulenc Sante
    Inventors: Dominique Petre, Edith Cerbelaud, Jean-Francois Mayaux, Patrice Yeh
  • Enzymic process for the synthesis of ammonium adipate
    Patent number: 5258292
    Abstract: The invention relates to an enzymic process for the synthesis of ammonium adipate by the hydrolysis of adipamide and/or ammonium adipamate by means of a particular polypeptide or a recombinant microorganism generating this polypeptide.
    Type: Grant
    Filed: November 22, 1991
    Date of Patent: November 2, 1993
    Assignee: Rhone-Poulenc Chimie
    Inventors: Patrice Yeh, Jean-Francois Mayaux, Edith Cerbelaud, Dominique Petre
  • Process for the preparation of optically active 2-arylpropionic acids and pharmaceutical compositions containing the same
    Patent number: 5089405
    Abstract: S Enantiomers of 2-arylpropionic acids are made by enantioselective hydrolysis of the corresponding racemic 2-arylpropionamides in the presence of a microorganism, or of an enzyme derived therefrom, able selectively to hydrolyze racemic .alpha.-phenylpropionamide to S .alpha.-phenylpropionic acid. The S Enantiomers obtained may be incorporated into antiinflammatory, analgesic and antipyretic compositions.
    Type: Grant
    Filed: July 26, 1989
    Date of Patent: February 18, 1992
    Assignee: Rhone-Poulenc Sante
    Inventors: Edith Cerbelaud, Dominique Petre
  • Process for the preparation of optically active 2-arylalkanoic acids
    Patent number: 5034329
    Abstract: Optically active 2-arylalkanoic acids are made by enantioselective hydrolysis of the corresponding racemic amides in the presence of a microorganism, or of an enzyme derived therefrom, able selectively to hydrolyse racemic .alpha.-phenylpropionamide to S .alpha.-phenylpropionic acid.
    Type: Grant
    Filed: January 27, 1989
    Date of Patent: July 23, 1991
    Assignee: Rhone-Poulenc Sante
    Inventors: Edith Cerbelaud, Dominique Petre