Abstract: Mechanisms and techniques allow a host computer system to control caching operations within a data storage system. In a typical implementation, the system of the invention operates within a host computer system to intercept requests for access to data stored within a data storage system that originate from applications, programs or other processes that perform (e.g., execute) on the host computer system or another computer system. Once intercepted, the host computer can examine such a request for access to data to determine if the request matches any prefetch criteria defined within a prefetch database provided by the system of the invention. As an example, prefetch criteria defined in a prefetch database can specify various requestors (e.g., applications, programs, processes, users, or the like) that can access data (e.g., specific files, databases, volumes, data types or the like) stored within the data storage system according to various data access techniques (e.g.