Patents by Inventor Edith Salot Harris

Edith Salot Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytoplasmic modulators of integrin binding
    Patent number: 5948891
    Abstract: The present invention relates to purified and isolated polynucleotides encoding a polypeptide which specifically bind to a cytoplasmic portion of an integrin. Specifically, the invention provides a FLP-1-encoding polynucleotide and the polypeptide product of the gene. Expression vectors comprising the polynucleotide, antibodies which recognize the polypeptide, hybridomas which secrete the antibodies, and method to identify modulators of interaction of the polypeptide with .beta..sub.7 subunits sequences are also provided.
    Type: Grant
    Filed: January 6, 1997
    Date of Patent: September 7, 1999
    Assignee: ICOS Corporation
    Inventors: Donald E. Staunton, Edith A. Salot Harris
  • Cytoplasmic Modulators of Integrin Binding/Signalling
    Patent number: 5922570
    Abstract: The present invention relates to purified and isolated polynucleotides encoding a polypeptide which specifically bind to a cytoplasmic portion of an integrin. Specifically, the invention provides a FLP-1-encoding polynucleotide and the polypeptide product of the gene. Expression vectors comprising the polynucleotide, antibodies which recognize the polypeptide, hybridomas which secrete the antibodies, and method to identify modulators of interaction of the polypeptide with .beta..sub.7 subunits sequences are also provided.
    Type: Grant
    Filed: January 5, 1996
    Date of Patent: July 13, 1999
    Assignee: ICOS Corporation
    Inventors: Donald E. Staunton, Edith Salot Harris
  • Cytoplasmic modulators of integrin binding/signalling
    Patent number: 5693483
    Abstract: The present invention relates to methods to identify modulators of integrin binding and/or signalling activity. Specifically the invention relates to a method to identify compounds which can alter the interaction between the cytoplasmic domain of a .beta..sub.1 integrin and a proteasome subunit protein.
    Type: Grant
    Filed: January 5, 1996
    Date of Patent: December 2, 1997
    Assignee: ICOS Corporation
    Inventors: Donald E. Staunton, Edith Salot Harris