Patents by Inventor Edmond Differding

Edmond Differding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8034958
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: October 11, 2011
    Assignee: UOB Pharma, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20100222576
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: February 17, 2010
    Publication date: September 2, 2010
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 7692028
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: April 6, 2010
    Assignee: UCB Pharma, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 7358276
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: April 15, 2008
    Assignee: UCB, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 7217826
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Grant
    Filed: January 4, 2005
    Date of Patent: May 15, 2007
    Assignee: UCB Farchim S.A.
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 6969770
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: November 29, 2005
    Assignee: U.C.B. Farchim S.A.
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20050171187
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 4, 2005
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20050171188
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 4, 2005
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Publication number: 20050159475
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Application
    Filed: January 4, 2005
    Publication date: July 21, 2005
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 6911461
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: June 28, 2005
    Assignee: UCB, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 6858740
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: February 22, 2005
    Assignee: UCB Farchim S.A.
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 6806287
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: October 19, 2004
    Assignee: UCB, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Publication number: 20040192757
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing &agr;-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-&agr;-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Application
    Filed: April 15, 2004
    Publication date: September 30, 2004
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • Compounds and methods for treatment of asthma, allergy and inflammatory disorders
    Patent number: 6797713
    Abstract: The present invention provides 1,4 substituted piperazines, 1,4 substituted piperidines, and 1-substituted, 4-alkylidenyl piperidines compounds. The compounds of the invention are dual acting molecules having both leukotriene inhibition properties as well as antihistaminergic properties. The compounds of the invention are useful for treating conditions in which there is likely to be a histamine and/or leukotriene component. These conditions include preferably asthma, seasonal and perennial allergic rhinitis, sinusitus, conjunctivitis, food allergy, scombroid poisoning, psoriasis, urticaria, pruritus, eczema, rheumatoid arthritis, inflammatory bowel disease, chronic obstructive pulmonary disease, thrombotic disease and otitis media. Also provided are methods of treating asthma and rhinitis by administering an effective asthma and rhinitis-relieving amount of the compounds to a subject in need thereof.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: September 28, 2004
    Assignee: UCB S.A.
    Inventors: Ralph Scannell, Pierre Chatelain, Anna Toy-Palmer, Edmond Differding, James Ellis, Marie-Agnes Lassoie, Michelle Young, Xiong Cai, Sajjat Hussoin, Gurmit Grewal, Timothy Lewis
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 6784197
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula (I) wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: August 31, 2004
    Assignee: UCB S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20040116507
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, 1
    Type: Application
    Filed: October 28, 2003
    Publication date: June 17, 2004
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USES
    Publication number: 20040092576
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing &agr;-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-&agr;-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Application
    Filed: July 1, 2003
    Publication date: May 13, 2004
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20040087646
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, 1
    Type: Application
    Filed: October 28, 2003
    Publication date: May 6, 2004
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 6713635
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing &agr;-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-&agr;-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: March 30, 2004
    Assignee: UCB Farchim S.A.
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • Compounds and methods for treatment of asthma, allergy and inflammatory disorders
    Publication number: 20040048875
    Abstract: The present invention provides 1,4 substituted piperazines, 1,4 substituted piperidines, and 1-substituted,4-alkylidenyl piperidines compounds. The compounds of the invention are dual acting molecules having both leukotriene inhibition properties as well as antihistaminergic properties. The compounds of the invention are useful for treating conditions in which there is likely to be a histamine and/or leukotriene component. These conditions include preferably asthma, seasonal and perennial allergic rhinitis, sinusitus, conjunctivitis, food allergy, scombroid poisoning, psoriasis, urticaria, pruritus, eczema, rheumatoid arthritis, inflammatory bowel disease, chronic obstructive pulmonary disease, thrombotic disease and otitis media. Also provided are methods of treating asthma and rhinitis by administering an effective asthma and rhinitis-relieving amount of the compounds to a subject in need thereof.
    Type: Application
    Filed: August 8, 2003
    Publication date: March 11, 2004
    Applicant: UCB S.A.
    Inventors: Ralph Scannell, Pierre Chatelain, Anna Toy-Palmer, Edmond Differding, James Ellis, Marie-Agnes Lassoie, Michelle Young, Xiong Cai, Sajjat Hussoin, Gurmit Grewal, Timothy Lewis