Patents by Inventor Edmund C. Kornfeld

Edmund C. Kornfeld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of pyrimido[4,5-g]quinolines in treating parkinsonism
    Patent number: 4599339
    Abstract: Trans-(.+-.)-2-Amino or substituted amino-4-permissibly-substituted 6-lower alkyl or allyl-5,5a,-6,7,8,9,9a,10-octahydropyrimido[4,5-g]quinolines, the corresponding trans-(-)-stereoisomers and salts thereof, useful in treating anxiety, Parkinson's Syndrome, sexual dysfunction, depression, hypertension and elevated prolactin levels, and intermediates useful for the synthesis thereof.
    Type: Grant
    Filed: November 1, 1984
    Date of Patent: July 8, 1986
    Assignee: Eli Lilly and Company
    Inventors: Cynthia L. Nichols, Edmund C. Kornfeld
  • Partially hydrogenated intermediate pyrazolo, pyrimido and thiazolo[1,4]benzoxazines
    Patent number: 4587336
    Abstract: Intermediates useful for the preparation of pyrazolo, pyrimido and thiazolo[1,4]benzoxazines, useful as dopamine agonists.
    Type: Grant
    Filed: August 5, 1985
    Date of Patent: May 6, 1986
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, Edmund C. Kornfeld
  • 1-Alkyl-6-pyrrolidino-octahydroquinolines
    Patent number: 4565871
    Abstract: Trans-(.+-.) or trans-(-)-2,4-permissibly-substituted-6-alkyl or allyl octahydropyrimido[4,5-g]quinolines and related compounds, ultraviolet light absorbers.
    Type: Grant
    Filed: December 11, 1984
    Date of Patent: January 21, 1986
    Assignee: Eli Lilly and Company
    Inventors: Cynthia L. Nicholas, Edmund C. Kornfeld, John M. Schaus
  • Partially hydrogenated pyrazolo, pyrimido and thiazolo[1,4]benzoxazines
    Patent number: 4552956
    Abstract: Pyrazolo, pyrimido and thiazolo[1,4]benzoxazines, useful as dopamine agonists.
    Type: Grant
    Filed: August 15, 1984
    Date of Patent: November 12, 1985
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, Edmund C. Kornfeld
  • Octahydrothiazolo[4,5-g]quinolines and use as prolactin secretion inhibitors
    Patent number: 4537893
    Abstract: Trans-(.+-.) 2 and/or 5-permissibly substituted octahydrothiazolo[4,5-g]quinolines and acid addition or quaternary salts thereof and, individual enantiomers thereof, useful as dopamine agonists.
    Type: Grant
    Filed: April 27, 1984
    Date of Patent: August 27, 1985
    Assignee: Eli Lilly and Company
    Inventors: Robert D. Titus, Edmund C. Kornfeld
  • 2-Mercaptopyrimidohexahydroquinolines and related compounds
    Patent number: 4507478
    Abstract: Trans-(.+-.) or trans-(-)-2,4-permissibly-substituted-6-alkyl or allyl octahydropyrimido[4,5-g]quinolines and related compounds, ultraviolet light absorbers.
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: March 26, 1985
    Assignee: Eli Lilly and Company
    Inventors: Cynthia L. Nichols, Edmund C. Kornfeld, John M. Schaus
  • Trans-( .+-.)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quino lines
    Patent number: 4501890
    Abstract: Trans-(.+-.)-2-Amino or substituted amino-4-permissibly-substituted 6-lower alkyl or allyl-5,5a,-6,7,8,9,9a,10-octahydropyrimido[4,5-g]quinolines, the corresponding trans-(-)-stereoisomers and salts thereof, useful in treating anxiety, Parkinson's Syndrome, sexual dysfunction, depression, hypertension and elevated prolactin levels, and intermediates useful for the synthesis thereof.
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: February 26, 1985
    Assignee: Eli Lilly and Company
    Inventors: Cynthia L. Nichols, Edmund C. Kornfeld
  • Hydroxyaminotetralincarboxamides
    Patent number: 4500545
    Abstract: o-Hydroxy tetralin carboxamides, substituted with an amino group in the aliphatic ring, are dopamine agonists.
    Type: Grant
    Filed: March 12, 1984
    Date of Patent: February 19, 1985
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld, Robert D. Titus
  • Hydroxyaminotetralincarboxamides
    Patent number: 4448990
    Abstract: o-Hydroxy tetralin carboxamides, substituted with an amino group in the aliphatic ring, are dopamine agonists.
    Type: Grant
    Filed: November 16, 1982
    Date of Patent: May 15, 1984
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld, Robert D. Titus
  • Method of using octahydro pyrazolo[3,4-g]quinolines
    Patent number: 4367231
    Abstract: Method of treating Parkinson's Syndrome by administering a tautomeric mixture of a 5-(C.sub.1 -C.sub.3)alkyl or allyl-7-permissibly substituted-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrazolo[3,4-g]quinolines.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: January 4, 1983
    Assignee: Eli Lilly and Company
    Inventors: Edmund C. Kornfeld, Nicholas J. Bach
  • Substituted 4,5,6,7-tetrahydro-1H (or 2H)-indazoles
    Patent number: 4322540
    Abstract: Amino-substituted-4,5,6,7-tetrahydro-1H(or 2H)-indazoles, useful as prolactin inhibitors and in treatment of Parkinson's Syndrome and intermediate 6-oxo-4,5,6,7-tetrahydro-1H(or 2H)-indazoles and 6-alkyloxy (or benzyloxy)-4,5-dihydro-1H(or 2H)indazoles.
    Type: Grant
    Filed: February 19, 1981
    Date of Patent: March 30, 1982
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld
  • Octahydro-2H-pyrrolo[3,4,-g]quinolines
    Patent number: 4311844
    Abstract: Octahydro-2H-pyrrolo[3,4-g]quinolines, useful as dopamine agonists, particularly as inhibitors of prolactin secretion and in treatment of Parkinsonism.
    Type: Grant
    Filed: March 9, 1981
    Date of Patent: January 19, 1982
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld
  • Octahydro-2H-pyrrolo[3,4-g]quinolines
    Patent number: 4282362
    Abstract: Octahydro-2H-pyrrolo[3,4-g]quinolines, useful as dopamine agonists, particularly as inhibitors of prolactin secretion and in treatment of Parkinsonism.
    Type: Grant
    Filed: April 18, 1980
    Date of Patent: August 4, 1981
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld
  • Amino-substituted-4,5,6,7-tetrahydro-1H (or 2H)-indazoles
    Patent number: 4276300
    Abstract: Amino-substituted-4,5,6,7-tetrahydro-1H (or 2H)-indazoles, useful as prolactin inhibitors and in treatment of Parkinson's Syndrome. Intermediate 6-keto(or 6-alkoxy or benzyloxy)-4,5,6,7-tetrahydro-1H (or 2H)-indazoles are also disclosed.
    Type: Grant
    Filed: March 15, 1979
    Date of Patent: June 30, 1981
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld
  • Tetrahydro-2H-benzo[c]pyrroles to inhibit prolactin secretion
    Patent number: 4264622
    Abstract: Tetrahydro-2H-benzo[c]pyrroles, useful as dopamine agonists, particularly as inhibitors of prolactin secretion and in treatment of Parkinson's syndrome.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: April 28, 1981
    Assignee: Eli Lilly and Company
    Inventors: Edmund C. Kornfeld, Nicholas J. Bach
  • 6-n-Propyl-8.alpha.-methoxymethyl or methylmercaptomethylergolines and related compounds
    Patent number: 4246265
    Abstract: D-6-n-propyl-8.alpha.-methoxymethyl or methylmercaptomethylergoline, dopaminergic drugs are used to treat Parkinsonism and to inhibit prolactin secretion.
    Type: Grant
    Filed: October 1, 1979
    Date of Patent: January 20, 1981
    Assignee: Eli Lilly and Company
    Inventors: Edmund C. Kornfeld, Nicholas J. Bach
  • Octahydro-2H-pyrrolo[3,4-g]quinolines
    Patent number: 4235909
    Abstract: Octahydro-2H-pyrrolo[3,4-g]quinolines, useful as dopamine agonists, particularly as inhibitors of prolactin secretion and in treatment of Parkinsonism.
    Type: Grant
    Filed: April 19, 1979
    Date of Patent: November 25, 1980
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld
  • Tetrahydro-2H-benzo[c]pyrroles
    Patent number: 4235776
    Abstract: Tetrahydro-2H-benzo[c]pyrroles, useful as dopamine agonists, particularly as inhibitors of prolactin secretion and in treatment of Parkinson's syndrome.
    Type: Grant
    Filed: March 15, 1979
    Date of Patent: November 25, 1980
    Assignee: Eli Lilly and Company
    Inventors: Edmund C. Kornfeld, Nicholas J. Bach
  • 1-And/or 7-substituted-6-hydroxy (or oxo)-3-decahydroquinoline carboxylic acids
    Patent number: 4230861
    Abstract: Octahydropyrazolo[3,4-g]quinolines, dopamine agonists, useful in treatment of Parkinsonism and in inhibiting secretion of prolactin.
    Type: Grant
    Filed: September 14, 1979
    Date of Patent: October 28, 1980
    Assignee: Eli Lilly and Company
    Inventors: Edmund C. Kornfeld, Nicholas J. Bach
  • 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
    Patent number: 4202979
    Abstract: 6-n-Propyl (ethyl or allyl)-8.beta.-methoxy-(methylsulfinyl, methylsulfonyl, or methylmercapto) methylergolines, 8-ergolenes or 9-ergolenes, useful as prolactin inhibitors and in the treatment of Parkinsonism.
    Type: Grant
    Filed: January 11, 1979
    Date of Patent: May 13, 1980
    Assignee: Eli Lilly and Company
    Inventors: Edmund C. Kornfeld, Nicholas J. Bach