Abstract: The sample temperature protection rack is designed to provide a holding area for enzymes and other compound samples and, at the same time maintain a pre-determined temperature range that prevents rapid degradation of the sample. The apparatus consists of a compact sample tube rack that contains coolant surrounded by a hard plastic shell. It has a removable thin plastic cover that is autoclavable to minimize the risk of sample contamination and can be disposable. The shell incorporates a tongue and groove system to allow for multiple units to be positioned together. The rack contains a plurality of rows of slots which will accommodate sample tubes and will accommodate variable sized tubes.