Patents by Inventor Edmund F. La Gamma

Edmund F. La Gamma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing genetically modified astrocytes and uses thereof
    Publication number: 20040071678
    Abstract: A genetically modified astrocyte for gene therapy is provided. The genetically modified astrocyte includes one or more stably introduced DNA sequences selected from DNA encoding a selectable marker, DNA encoding a poison pill, and DNA encoding a molecule useful for gene therapy. The genetically modified astrocyte may be produced utilizing plasmids and non-viral transfection methods, as are also provided by the subject invention. Methods for producing and utilizing the genetically modified astrocytes and regulating the engineered products, as well as kits thereof, are further provided.
    Type: Application
    Filed: September 30, 2003
    Publication date: April 15, 2004
    Applicant: Research Foundation of the State University of New York
    Inventors: Edmund F. La Gamma, Gary Weisinger, Robert E. Strecker, Nicholas J. Lenn
  • Use of G-CSF to enhance the immune system in neonates
    Patent number: 6162426
    Abstract: The invention relates to the use of Granulocyte Colony Stimulating Factor (G-CSF) to enhance the immune system in neonates by increasing the Absolute Neutrophil Count and/or increasing the Fc.sub..gamma. receptor density on the surface of neutrophils in neonates. More particularly, the invention relates to the use of G-CSF to enhance neutrophil production and/or Fc.sub..gamma. receptor density in very Low Birth Weight (VLBW) neonates, pre-eclamptic neutropenic neonates, and septic-neutropenic neonates. The invention also includes the use of G-CSF in association with IUGG to enhance opsonziation of infectious organisms either by prophylaxis or as a therapeutic intervention.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: December 19, 2000
    Inventor: Edmund F. La Gamma
  • Method of producing genetically modified astrocytes and uses thereof
    Patent number: 6106827
    Abstract: A genetically modified astrocyte for gene therapy is provided. The genetically modified astrocyte includes one or more stably introduced DNA sequences selected from DNA encoding a selectable marker, DNA encoding a poison pill, and DNA encoding a molecule useful for gene therapy. The genetically modified astrocyte may be produced utilizing plasmids and non-viral transfection methods, as are also provided by the subject invention. Methods for producing and utilizing the genetically modified astrocytes and regulating the engineered products, as well as kits thereof, are further provided.
    Type: Grant
    Filed: May 24, 1997
    Date of Patent: August 22, 2000
    Assignee: The Research Foundation of State University of New York
    Inventors: Edmund F. La Gamma, Gary Weisinger, Robert E. Strecker, Nicholas J. Lenn