Patents by Inventor Edmund Moran

Edmund Moran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diaryl ether beta2 adrenergic receptor agonists
    Publication number: 20080113981
    Abstract: The invention provides novel ?2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with ?2 adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: November 19, 2007
    Publication date: May 15, 2008
    Inventors: Robert McKinnell, Edmund Moran
  • Cross-linked glycopeptide-cephalosporin antibiotics
    Publication number: 20080108558
    Abstract: This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 8, 2008
    Inventors: Paul Fatheree, Martin Linsell, Daniel Long, Daniel Marquess, Edmund Moran, Matthew Nodwell, S. Derek Turner, James Aggen
  • Cross-linked glycopeptide - cephalosporin antibiotics
    Publication number: 20080103299
    Abstract: This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: December 19, 2007
    Publication date: May 1, 2008
    Inventors: Paul Fatheree, Martin Linsell, Daniel Marquess, Daniel Long, Jason Chinn, Matthew Nodwell, Edmund Moran, James Aggen
  • Cross-linked glycopeptide-cephalosporin antibiotics
    Publication number: 20080045721
    Abstract: This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: August 24, 2007
    Publication date: February 21, 2008
    Inventors: Paul Fatheree, Martin Linsell, Daniel Long, Daniel Marquess, Edmund Moran, Matthew Nodwell, S. Derek Turner, James Aggen
  • Cross-linked glycopeptide-cephalosporin antibiotics
    Publication number: 20080039611
    Abstract: This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: August 24, 2007
    Publication date: February 14, 2008
    Inventors: Paul Fatheree, Martin Linsell, Daniel Long, Daniel Marquess, Edmund Moran, Matthew Nodwell, S. Derek Turner, James Aggen
  • Cross-lined glycopeptide-cephalosporin antibiotics
    Publication number: 20080039374
    Abstract: This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: August 24, 2007
    Publication date: February 14, 2008
    Inventors: Paul Fatheree, Martin Linsell, Daniel Long, Daniel Marquess, Edmund Moran, Matthew Nodwell, S. Derek Turner, James Aggen
  • Aryl aniline beta2 adrenergic receptor agonists
    Publication number: 20070225329
    Abstract: The invention provides novel ?2 adrenergic receptor agonist compounds of formula (I): wherein R1-R13 and w have any of the values described in the specification. The invention also provides combinations of such compounds and other therapeutic agents, pharmaceutical compositions comprising such compounds and combinations, methods of using such compounds to treat diseases associated with ?2 adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: May 22, 2007
    Publication date: September 27, 2007
    Inventors: Edmund Moran, John Jacobsen, Michael Leadbetter, Matthew Nodwell, Sean Trapp, James Aggen, Timothy Church
  • Novel antibacterial agents
    Publication number: 20070196859
    Abstract: This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked ) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall.
    Type: Application
    Filed: November 21, 2006
    Publication date: August 23, 2007
    Inventors: Burton Christensen, Edmund Moran, John Griffin, J. Judice, YongQi Mu, John Pace, Mathai Mammen, James Aggen
  • Beta2-adrenergic receptor agonists
    Publication number: 20070179179
    Abstract: Disclosed are multibinding compounds which are ?2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.
    Type: Application
    Filed: April 5, 2007
    Publication date: August 2, 2007
    Inventors: Edmund Moran, Seok-Ki Choi
  • Novel antibacterial agents
    Publication number: 20070154948
    Abstract: This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall.
    Type: Application
    Filed: November 21, 2006
    Publication date: July 5, 2007
    Inventors: Burton Christensen, Edmund Moran, John Griffin, J. Judice, YongQi Mu, John Pace, Mathai Mammen, James Aggen
  • Novel antibacterial agents
    Publication number: 20070134729
    Abstract: This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall.
    Type: Application
    Filed: November 21, 2006
    Publication date: June 14, 2007
    Inventors: Burton Christensen, Edmund Moran, John Griffin, J. Judice, YongQi Mu, John Pace, Mathai Mammen, James Aggen
  • Cross-linked glycopeptide-cephalosporin antibiotics
    Publication number: 20060189517
    Abstract: This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: April 17, 2006
    Publication date: August 24, 2006
    Inventors: Paul Fatheree, Martin Linsell, Daniel Marquess, Sean Trapp, Edmund Moran, James Aggen
  • Beta 2-adrenergic receptor agonists
    Publication number: 20060183918
    Abstract: Disclosed are multibinding compounds which are ?2-adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.
    Type: Application
    Filed: April 10, 2006
    Publication date: August 17, 2006
    Inventors: Edmund Moran, Seok-Ki Choi
  • Aryl aniline beta2 adrenergic receptor agonists
    Publication number: 20060178410
    Abstract: The invention provides novel ?2 adrenergic receptor agonist compounds of formula (I): wherein R1-R13 and w have any of the values described in the specification. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with ?2 adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: April 10, 2006
    Publication date: August 10, 2006
    Inventors: Edmund Moran, John Jacobsen, Michael Leadbetter, James Aggen, Timothy Church
  • Cross-linked glycopeptide-cephalosporin antibiotics
    Publication number: 20060128612
    Abstract: This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 15, 2006
    Inventors: Paul Fatheree, Martin Linsell, Daniel Marquess, Daniel Long, Jason Chinn, Matthew Nodwell, Edmund Moran, James Aggen
  • Diaryl ether beta2 adrenergic receptor agonists
    Publication number: 20060019991
    Abstract: The invention provides novel ?2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with ?2 adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: July 20, 2005
    Publication date: January 26, 2006
    Applicant: Theravance, Inc.
    Inventors: Robert McKinnell, Edmund Moran
  • Beta2-adrenergic receptor agonists
    Publication number: 20050261338
    Abstract: Disclosed are multibinding compounds which are ?2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.
    Type: Application
    Filed: February 2, 2005
    Publication date: November 24, 2005
    Inventors: Edmund Moran, Seok-Ki Choi
  • Protein kinase inhibitors
    Publication number: 20050261318
    Abstract: Disclosed are compounds which inhibit or modulate the activity of protein kinases and pharmaceutical compositions containing such compounds. The disclosed compound contain two or more ligand moieties covalently linked together by one or more linking groups. Such compounds are useful for treating diseases or medical disorders mediated by protein kinases.
    Type: Application
    Filed: July 11, 2005
    Publication date: November 24, 2005
    Inventors: John Griffin, Yu-Hua Ji, Edmund Moran, Jonathan Wray
  • Cross-linked glycopeptide - cephalosporin antibiotics
    Publication number: 20050239691
    Abstract: This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: June 30, 2005
    Publication date: October 27, 2005
    Inventors: Paul Fatheree, Martin Linsell, Daniel Long, Daniel Marquess, Edmund Moran, Matthew Nodwell, S. Turner, James Aggen
  • Beta 2-adrenergic receptor agonists
    Publication number: 20050209275
    Abstract: Disclosed are multibinding compounds which are ?2-adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.
    Type: Application
    Filed: May 10, 2005
    Publication date: September 22, 2005
    Inventors: Edmund Moran, Seok-Ki Choi