Patents by Inventor Edna Ben-Asher

Edna Ben-Asher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Markers associated with the therapeutic efficacy of glatiramer acetate
    Publication number: 20100285600
    Abstract: The present invention is directed to methods and kits based, at least in part, on the identification of allele-specific responsiveness or non-responsiveness to glatiramer acetate for the treatment of autoimmune disorders, such as relapsing-remitting multiple sclerosis. The allele-specific responsiveness or non-responsiveness is based on polymorphisms in the following genes, CTSS, MBP, TCRB, CD95, CD86, IL-1R1, CD80, SCYA5, MMP9, MOG, SPP1 and IL-12RB2.
    Type: Application
    Filed: February 22, 2010
    Publication date: November 11, 2010
    Inventors: Doron Lancet, Jacques Beckmann, Nili Avidan, Edna Ben-Asher, Clara Singer, Liat Hayardeny, Dan Goldstaub, Iris Grossman, Ariel Miller
  • Markers associated with the therapeutic efficacy of glatiramer acetate
    Publication number: 20060240463
    Abstract: The present invention is directed to methods and kits based, at least in part, on the identification of allele-specific responsiveness or non-responsiveness to glatiramer acetate for the treatment of immune disorders, such as relapsing-remitting multiple sclerosis. The allele-specific responsiveness or non-responsiveness is based on polymorphisms in the following genes, CTSS, MBP, TCRB, CD95, CD86, IL-1R1, CD80, SCYA5, MMP9, MOG, SPP1 and IL-12RB2.
    Type: Application
    Filed: April 24, 2006
    Publication date: October 26, 2006
    Inventors: Doron Lancet, Jacques Beckmann, Nili Avidan, Edna Ben-Asher, Dan Goldstaub, Liat Hayardeny, Iris Grossman, Ariel Miller, Clara Singer
  • Erythrocyte differentiation factor, gene encoding same, and methods of use thereof
    Publication number: 20060154331
    Abstract: The present invention relates to an erythrocyte differentiation factor designed Codanin-1, and to an isolated nucleic acid which encodes for the differentiation factor. Mutations in the differentiation factor are associated with Congenital Dyserythropoietic Anemias (CDA), a group of inherited red blood cell disorders associated with dysplastic changes in late erythroid precursors. The present invention further relates to uses of the differentiation factor to promote the differentiation of hematopoietic stem cells to erythrocytes, as well as for the treatment and diagnosis of anemia.
    Type: Application
    Filed: October 14, 2003
    Publication date: July 13, 2006
    Inventors: Nili Avidan, Edna Ben-Asher, Tavyia Olender, Doron Lancet, Jacques Beckmann, Hannah Tamary, Orly Dgany
  • Pharmaceutical compositions comprising tetrahydropyrimidine derivates
    Patent number: 5789414
    Abstract: A pharmaceutical composition comprising as active ingredients at least two tetrahydropyrimidine derivatives selected from (a) 2-methyl-4-carboxy-3,4,5,6-tetrahydropyrimidine ?THP(B)! or a salt thereof, and (b) 2-methyl-4-carboxy-5-hydroxy-3,4,5,6-tetrahydropyrimidine ?THP(A)!, or a salt, a 5-ether or a 5-ester thereof, and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: January 28, 1993
    Date of Patent: August 4, 1998
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Aviva Lapidot, Livia Inbar, Edna Ben-Asher, Yosef Aloni, deceased