Patents by Inventor Edna MEILIN

Edna MEILIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL SHEDDING BLOCKING AGENTS
    Publication number: 20220169732
    Abstract: Agents that are less than 100 kilodaltons, bind a membranal immune receptor on a surface of a cell and inhibit proteolytic cleavage of the immune receptor are provided. Methods of treating cancer and improving immunotherapy comprising administering the agents are also provided.
    Type: Application
    Filed: March 12, 2020
    Publication date: June 2, 2022
    Inventors: Motti HAKIM, Anna FRIDMAN-DROR, Dror ALISHEKEVITZ, Edna MEILIN, Ilana MANDEL, Tehila BEN-MOSHE, Avidor SHULMAN, Yair SAPIR
  • A METHOD FOR IMMUNOSUPPRESSION
    Publication number: 20220153845
    Abstract: The present invention, in some embodiments thereof, is directed to a method for suppressing an immune response in a subject, including administering to the subject a therapeutically effective amount of an agent having specific binding affinity to a soluble immune receptor.
    Type: Application
    Filed: March 12, 2020
    Publication date: May 19, 2022
    Inventors: Motti HAKIM, Dror ALISHEKEVITZ, Edna MEILIN, Ilana MANDEL, Tehila BEN-MOSHE, Yair SAPIR, Avidor SHULMAN
  • METHODS AND COMPOSITIONS FOR DECREASING SOLUBLE IMMUNE RECEPTOR CD28
    Publication number: 20210047411
    Abstract: Methods of treating cancer and improving immunotherapies comprising decreasing soluble immune receptor levels are provided. Agents that bind membranal immune receptor and inhibit proteolytic cleavage of the receptor and agents that bind soluble immune receptor and that are neither receptor agonists nor antagonists are also provided, as are methods of producing these agents.
    Type: Application
    Filed: March 14, 2019
    Publication date: February 18, 2021
    Inventors: Motti HAKIM, Dror ALISHEKEVITZ, Dana HAVES ZIV, Edna MEILIN, Yair SAPIR, Avidor SHULMAN, Tehila BEN-MOSHE, Ilana MANDEL
  • Compositions comprising anti-CEACAM1 and anti-PD antibodies for cancer therapy
    Patent number: 10081679
    Abstract: The present invention provides compositions comprising anti-CEACAM1 antibodies, compositions comprising antibodies capable of inhibiting or blocking the interaction between PD-1 and its ligands, and methods for their combined use in treating cancer.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: September 25, 2018
    Assignee: CCAM BIOTHERAPEUTICS LTD.
    Inventors: Tehila Ben-Moshe, Yair Sapir, Ilana Mandel, Edna Meilin
  • COMPOSITIONS COMPRISING ANTI-CEACAM1 AND ANTI-PD ANTIBODIES FOR CANCER THERAPY
    Publication number: 20170166637
    Abstract: The present invention provides compositions comprising anti-CEACAM1 antibodies, compositions comprising antibodies capable of inhibiting or blocking the interaction between PD-1 and its ligands, and methods for their combined use in treating cancer.
    Type: Application
    Filed: November 25, 2014
    Publication date: June 15, 2017
    Applicant: CCAM BIOTHERAPEUTICS LTD.
    Inventors: Tehila BEN-MOSHE, Yair SAPIR, Ilana MANDEL, Edna MEILIN