Abstract: The present invention relates to a process for the preparation of compounds endowed with phosphodiesterase (PDE4) inhibitory activity having formula (I). The invention also relates to the process for the isolation by crystallization of the compound (I) and to its use for the preparation of pharmaceutical compositions for inhalation in combination with suitable carriers or vehicles. The present invention also relates to solvates and crystal forms of a compound of formula (I). The synthesized product is suitable for use in pharmaceutical applications for instance in the treatment of respiratory diseases.

Abstract: The present invention relates to a process for the preparation of compounds endowed with phosphodiesterase (PDE4) inhibitory activity having formula (I). The invention also relates to the process for the isolation by crystallization of the compound (I) and to its use for the preparation of pharmaceutical compositions for inhalation in combination with suitable carriers or vehicles. The present invention also relates to solvates and crystal forms of a compound of formula (I). The synthesized product is suitable for use in pharmaceutical applications for instance in the treatment of respiratory diseases.

Abstract: A supporting device for a portable processing and/or telecommunication apparatus or an accessory having a first portion adapted to be supported by a supporting structure and a second portion having magnetic elements for retaining the portable processing and/or telecommunication apparatus or accessory is provided. The first and second portions are joined together in pivotable manner through a hinge allowing rotation of one of the first and second portions with respect to the other. The supporting device is adapted to assume a first configuration of minimum size in which the second portion is superimposed on the first portion, and at least a second configuration of use in which the second portion is rotated at a selectable angle with respect to the first portion, the first and second portions being hinged so that the supporting device opens like a book from the configuration of minimum size to a selected configuration of use.

Abstract: A fabrication method of an elastomer breath structure includes the steps of applying a liquid elastomer onto a substrate an initial curing of the liquid elastomer on the substrate partially into a partially cured polymer, condensation of water droplets from the environment onto the partially cured polymer, and finishing curing of the partially cured polymer with parallel removal of the water droplets creating surface dimples on the cured elastomer.

Abstract: Disclosed is a process for making a diamond tool for processing ceramic starting from a mixture of aluminum-based powders in order to obtain a grinding wheel for an eco-friendly squaring of ceramic.